Gene name: PTP2
Reference locus (S288C): YOR208W
Gene biotype: protein_coding
Description: Tyrosine-protein phosphatase 2; Nuclear phosphotyrosine-specific phosphatase involved in osmosensing; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; with Msg5p co-regulates the calcium signaling pathway
Top 10 interactors (score): HOG1 (0.999); SLT2 (0.99); PTC1 (0.982); FUS3 (0.976); PTP3 (0.975); KSS1 (0.969); PBS2 (0.948); PTC2 (0.921); MSG5 (0.913); SLN1 (0.908); YVH1 (0.872); SSK1 (0.868); MKK1 (0.856); PTC3 (0.853); SSK2 (0.852); YPD1 (0.841); SHO1 (0.828); STE11 (0.817); HKR1 (0.811); NBP2 (0.802)
Homologues (species, bitscore): PTPRE (Homo sapiens, 101.3); Ptpn20 (Mus musculus, 105.1); ptpreb (Danio rerio, 114.0); ptprb (Xenopus tropicalis, 100.9); Ptp99A (Drosophila melanogaster, 97.1); Y41D4A.5 (Caenorhabditis elegans, 102.1); PTP1 (Arabidopsis thaliana, 82.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:724707-726959:+ | gene-YOR208W_AKU4011 | rna-NM_001183627.3_AKU4011 | cds-NP_014851.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:126746-128998:+ | gene-YOR208W_BG1 | rna-NM_001183627.3_BG1 | cds-NP_014851.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:709542-711794:+ | gene-YOR208W_Bruggeman | rna-NM_001183627.3_Bruggeman | cds-NP_014851.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:710820-713072:+ | gene-YOR208W_CAT1 | rna-NM_001183627.3_CAT1 | cds-NP_014851.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:707694-709946:+ | gene-YOR208W_CBS1585 | rna-NM_001183627.3_CBS1585 | cds-NP_014851.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:706385-708637:+ | gene-YOR208W_CBS436 | rna-NM_001183627.3_CBS436 | cds-NP_014851.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:704812-707064:+ | gene-YOR208W_CBS6412 | rna-NM_001183627.3_CBS6412 | cds-NP_014851.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:713451-715703:+ | gene-YOR208W_CBS6413 | rna-NM_001183627.3_CBS6413 | cds-NP_014851.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:733689-735941:+ | gene-YOR208W_CENPK1137D | rna-NM_001183627.3_CENPK1137D | cds-NP_014851.3_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:700847-703099:+ | gene-YOR208W_EthanolRed | rna-NM_001183627.3_EthanolRed | cds-NP_014851.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:706244-708496:+ | gene-YOR208W_FaliES1 | rna-NM_001183627.3_FaliES1 | cds-NP_014851.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:118262-120514:- | gene-YOR208W_JAY291 | rna-NM_001183627.3_JAY291 | cds-NP_014851.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:713504-715756:+ | gene-YOR208W_MUCL30387 | rna-NM_001183627.3_MUCL30387 | cds-NP_014851.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:720921-723173:+ | gene-YOR208W_MUCL30388 | rna-NM_001183627.3_MUCL30388 | cds-NP_014851.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:715023-717275:+ | gene-YOR208W_MUCL39482 | rna-NM_001183627.3_MUCL39482 | cds-NP_014851.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:724607-726859:+ | gene-YOR208W_MUCL42920 | rna-NM_001183627.3_MUCL42920 | cds-NP_014851.3_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:733814-736066:+ | gene-YOR208W_NCIM3186 | rna-NM_001183627.3_NCIM3186 | cds-NP_014851.3_NCIM3186 | 88.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:715121-717373:+ | gene-YOR208W_NCYC1407 | rna-NM_001183627.3_NCYC1407 | cds-NP_014851.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:714519-716771:+ | gene-YOR208W_PE2H3 | rna-NM_001183627.3_PE2H3 | cds-NP_014851.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:724896-727148:+ | gene-YOR208W_PE2H4 | rna-NM_001183627.3_PE2H4 | cds-NP_014851.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:733925-736177:+ | gene-YOR208W_S288C | rna-NM_001183627.3_S288C | cds-NP_014851.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:143926-146178:+ | gene-YOR208W_SA1 | rna-NM_001183627.3_SA1 | cds-NP_014851.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:705429-707681:+ | gene-YOR208W_ThermosaccDry | rna-NM_001183627.3_ThermosaccDry | cds-NP_014851.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:768960-771212:+ | gene-YOR208W_VR1 | rna-NM_001183627.3_VR1 | cds-NP_014851.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:438331-440583:+ | gene-YOR208W_ZTW1 | rna-NM_001183627.3_ZTW1 | cds-NP_014851.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:711281-713536:+ | gene-YOR208W_Sparadoxus | rna-NM_001183627.3_Sparadoxus | cds-NP_014851.3_Sparadoxus | 87.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |