PTP1 (YDL230W)


Gene profile

Gene name: PTP1
Reference locus (S288C): YDL230W
Gene biotype: protein_coding

Description: Tyrosine-protein phosphatase 1; Phosphotyrosine-specific protein phosphatase; dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria; proposed to be a negative regulator of filamentation; Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily

Top 10 interactors (score): HOG1 (0.999); PTC1 (0.874); PBS2 (0.851); PTC2 (0.837); PTP3 (0.824); SLT2 (0.823); FUS3 (0.82); MIH1 (0.763); PTC5 (0.754); MSG5 (0.742); SWE1 (0.712); GUT2 (0.708); PPQ1 (0.703); SDP1 (0.692); YCH1 (0.685); KDX1 (0.685); RSR1 (0.676); PTC3 (0.667); KSS1 (0.662); FPR3 (0.654)

Homologues (species, bitscore): PTPRS (Homo sapiens, 139.8); Ptprd (Mus musculus, 137.5); ptprsa (Danio rerio, 139.4); ptprf (Xenopus tropicalis, 137.9); Ptp10D (Drosophila melanogaster, 134.8); ptp-4 (Caenorhabditis elegans, 134.4); PTP1 (Arabidopsis thaliana, 117.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:25802-26809:+ gene-YDL230W_AKU4011 rna-NM_001180290.1_AKU4011 cds-NP_010051.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000077.1:39643-40650:- gene-YDL230W_BG1 rna-NM_001180290.1_BG1 cds-NP_010051.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:41521-42528:+ gene-YDL230W_Bruggeman rna-NM_001180290.1_Bruggeman cds-NP_010051.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:44442-45449:+ gene-YDL230W_CAT1 rna-NM_001180290.1_CAT1 cds-NP_010051.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:25177-26184:+ gene-YDL230W_CBS1585 rna-NM_001180290.1_CBS1585 cds-NP_010051.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:41946-42953:+ gene-YDL230W_CBS436 rna-NM_001180290.1_CBS436 cds-NP_010051.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:25680-26687:+ gene-YDL230W_CBS6412 rna-NM_001180290.1_CBS6412 cds-NP_010051.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:42562-43569:+ gene-YDL230W_CBS6413 rna-NM_001180290.1_CBS6413 cds-NP_010051.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:41668-42675:+ gene-YDL230W_CENPK1137D rna-NM_001180290.1_CENPK1137D cds-NP_010051.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:39394-40401:+ gene-YDL230W_EthanolRed rna-NM_001180290.1_EthanolRed cds-NP_010051.1_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:42696-43703:+ gene-YDL230W_FaliES1 rna-NM_001180290.1_FaliES1 cds-NP_010051.1_FaliES1 99.5 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000011.1:822-1829:- gene-YDL230W_JAY291 rna-NM_001180290.1_JAY291 cds-NP_010051.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:40817-41824:+ gene-YDL230W_MUCL30387 rna-NM_001180290.1_MUCL30387 cds-NP_010051.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:30384-31391:+ gene-YDL230W_MUCL30388 rna-NM_001180290.1_MUCL30388 cds-NP_010051.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:25771-26778:+ gene-YDL230W_MUCL39482 rna-NM_001180290.1_MUCL39482 cds-NP_010051.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:41958-42965:+ gene-YDL230W_MUCL42920 rna-NM_001180290.1_MUCL42920 cds-NP_010051.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:42623-43630:+ gene-YDL230W_NCIM3186 rna-NM_001180290.1_NCIM3186 cds-NP_010051.1_NCIM3186 99.4 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:25727-26734:+ gene-YDL230W_NCYC1407 rna-NM_001180290.1_NCYC1407 cds-NP_010051.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:33012-34019:+ gene-YDL230W_PE2H3 rna-NM_001180290.1_PE2H3 cds-NP_010051.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:33022-34029:+ gene-YDL230W_PE2H4 rna-NM_001180290.1_PE2H4 cds-NP_010051.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:42700-43707:+ gene-YDL230W_S288C rna-NM_001180290.1_S288C cds-NP_010051.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000107.1:607-1614:- gene-YDL230W_SA1 rna-NM_001180290.1_SA1 cds-NP_010051.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:42824-43831:+ gene-YDL230W_ThermosaccDry rna-NM_001180290.1_ThermosaccDry cds-NP_010051.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:42751-43758:+ gene-YDL230W_VR1 rna-NM_001180290.1_VR1 cds-NP_010051.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:41882-42889:+ gene-YDL230W_ZTW1 rna-NM_001180290.1_ZTW1 cds-NP_010051.1_ZTW1 99.5 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:45175-46182:+ gene-YDL230W_Sparadoxus rna-NM_001180290.1_Sparadoxus cds-NP_010051.1_Sparadoxus 90.2 100.0 Verified 1 1 1 False True False False False

Additional files