Gene name: PTK2
Reference locus (S288C): YJR059W
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase PTK2/STK2; Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication
Top 10 interactors (score): MIH1 (0.918); RAD51 (0.914); SKY1 (0.893); PMA1 (0.881); YCK1 (0.789); YCK2 (0.789); YJR061W (0.69); TRK1 (0.685); KNS1 (0.64); YGK3 (0.637); SDS24 (0.619); APS2 (0.615); PKP2 (0.59); YAK1 (0.571); FIP1 (0.564); HYM1 (0.562); PMP3 (0.555); TSL1 (0.544); KHA1 (0.542); CCT5 (0.54)
Homologues (species, bitscore): TSSK6 (Homo sapiens, 93.6); Tssk6 (Mus musculus, 95.1); nuak1 (Danio rerio, 83.6); nuak1 (Xenopus tropicalis, 85.1); par-1 (Drosophila melanogaster, 84.0); R02C2.6 (Caenorhabditis elegans, 95.9); SIP3 (Arabidopsis thaliana, 102.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:517318-519774:+ | gene-YJR059W_AKU4011 | rna-NM_001181717.3_AKU4011 | cds-NP_012593.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:87849-90305:- | gene-YJR059W_BG1 | rna-NM_001181717.3_BG1 | cds-NP_012593.3_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:530824-533280:+ | gene-YJR059W_Bruggeman | rna-NM_001181717.3_Bruggeman | cds-NP_012593.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:535137-537593:+ | gene-YJR059W_CAT1 | rna-NM_001181717.3_CAT1 | cds-NP_012593.3_CAT1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:529382-531838:+ | gene-YJR059W_CBS1585 | rna-NM_001181717.3_CBS1585 | cds-NP_012593.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:547451-549907:+ | gene-YJR059W_CBS436 | rna-NM_001181717.3_CBS436 | cds-NP_012593.3_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:516531-518987:+ | gene-YJR059W_CBS6412 | rna-NM_001181717.3_CBS6412 | cds-NP_012593.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:518827-521283:+ | gene-YJR059W_CBS6413 | rna-NM_001181717.3_CBS6413 | cds-NP_012593.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:528145-530601:+ | gene-YJR059W_CENPK1137D | rna-NM_001181717.3_CENPK1137D | cds-NP_012593.3_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:521711-524167:+ | gene-YJR059W_EthanolRed | rna-NM_001181717.3_EthanolRed | cds-NP_012593.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:533177-535633:+ | gene-YJR059W_FaliES1 | rna-NM_001181717.3_FaliES1 | cds-NP_012593.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:153756-156212:- | gene-YJR059W_JAY291 | rna-NM_001181717.3_JAY291 | cds-NP_012593.3_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:531362-533818:+ | gene-YJR059W_MUCL30387 | rna-NM_001181717.3_MUCL30387 | cds-NP_012593.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:528636-531104:+ | gene-YJR059W_MUCL30388 | rna-NM_001181717.3_MUCL30388 | cds-NP_012593.3_MUCL30388 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:522844-525300:+ | gene-YJR059W_MUCL39482 | rna-NM_001181717.3_MUCL39482 | cds-NP_012593.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:527071-529539:+ | gene-YJR059W_MUCL42920 | rna-NM_001181717.3_MUCL42920 | cds-NP_012593.3_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:545766-548222:+ | gene-YJR059W_NCIM3186 | rna-NM_001181717.3_NCIM3186 | cds-NP_012593.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:520408-522864:+ | gene-YJR059W_NCYC1407 | rna-NM_001181717.3_NCYC1407 | cds-NP_012593.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:538300-540756:+ | gene-YJR059W_PE2H3 | rna-NM_001181717.3_PE2H3 | cds-NP_012593.3_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:531996-534452:+ | gene-YJR059W_PE2H4 | rna-NM_001181717.3_PE2H4 | cds-NP_012593.3_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:545787-548243:+ | gene-YJR059W_S288C | rna-NM_001181717.3_S288C | cds-NP_012593.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000038.1:4366-6822:+ | gene-YJR059W_SA1 | rna-NM_001181717.3_SA1 | cds-NP_012593.3_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:527107-529563:+ | gene-YJR059W_ThermosaccDry | rna-NM_001181717.3_ThermosaccDry | cds-NP_012593.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:528986-531442:+ | gene-YJR059W_VR1 | rna-NM_001181717.3_VR1 | cds-NP_012593.3_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:506496-508964:+ | gene-YJR059W_ZTW1 | rna-NM_001181717.3_ZTW1 | cds-NP_012593.3_ZTW1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:539921-542377:+ | gene-YJR059W_Sparadoxus | rna-NM_001181717.3_Sparadoxus | cds-NP_012593.3_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |