PTK1 (YKL198C)


Gene profile

Gene name: PTK1
Reference locus (S288C): YKL198C
Gene biotype: protein_coding

Description: Serine/threonine-protein kinase PTK1/STK1; Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication

Top 10 interactors (score): SKG1 (0.824); YKL033W-A (0.813); YPR089W (0.748); YJL107C (0.747); PIR5 (0.746); TPH3 (0.744); TMA23 (0.711); PRM10 (0.71); EMC3 (0.701); ICS2 (0.699); PFF1 (0.693); GPI14 (0.69); MBF1 (0.688); SEA4 (0.675); TRM2 (0.669); STE23 (0.653); KSH1 (0.65); SKY1 (0.65); YJL127C-B (0.611); YIL156W-B (0.611)

Homologues (species, bitscore): TSSK6 (Homo sapiens, 94.0); Tssk6 (Mus musculus, 95.1); mark4a (Danio rerio, 92.0); mark2 (Xenopus tropicalis, 90.5); Sik2 (Drosophila melanogaster, 92.0); R02C2.6 (Caenorhabditis elegans, 98.6); SIP3 (Arabidopsis thaliana, 98.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:54597-56579:- gene-YKL198C_AKU4011 rna-NM_001179764.2_AKU4011 cds-NP_012723.3_AKU4011 97.9 99.5 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:31550-33541:- gene-YKL198C_BG1 rna-NM_001179764.2_BG1 cds-NP_012723.3_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:72250-74232:- gene-YKL198C_Bruggeman rna-NM_001179764.2_Bruggeman cds-NP_012723.3_Bruggeman 98.0 99.5 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:67416-69398:- gene-YKL198C_CAT1 rna-NM_001179764.2_CAT1 cds-NP_012723.3_CAT1 99.0 99.5 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:66582-68564:- gene-YKL198C_CBS1585 rna-NM_001179764.2_CBS1585 cds-NP_012723.3_CBS1585 98.0 99.5 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:65800-67791:- gene-YKL198C_CBS436 rna-NM_001179764.2_CBS436 cds-NP_012723.3_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:51839-53821:- gene-YKL198C_CBS6412 rna-NM_001179764.2_CBS6412 cds-NP_012723.3_CBS6412 98.0 99.5 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:67219-69201:- gene-YKL198C_CBS6413 rna-NM_001179764.2_CBS6413 cds-NP_012723.3_CBS6413 98.1 99.5 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:68013-69995:- gene-YKL198C_CENPK1137D rna-NM_001179764.2_CENPK1137D cds-NP_012723.3_CENPK1137D 98.0 99.5 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:66029-68011:- gene-YKL198C_EthanolRed rna-NM_001179764.2_EthanolRed cds-NP_012723.3_EthanolRed 98.0 99.5 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:66088-68070:- gene-YKL198C_FaliES1 rna-NM_001179764.2_FaliES1 cds-NP_012723.3_FaliES1 98.0 99.5 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000006.2:65633-67624:- gene-YKL198C_JAY291 rna-NM_001179764.2_JAY291 cds-NP_012723.3_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:74781-76763:- gene-YKL198C_MUCL30387 rna-NM_001179764.2_MUCL30387 cds-NP_012723.3_MUCL30387 98.0 99.5 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:68873-70855:- gene-YKL198C_MUCL30388 rna-NM_001179764.2_MUCL30388 cds-NP_012723.3_MUCL30388 98.1 99.5 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:66639-68621:- gene-YKL198C_MUCL39482 rna-NM_001179764.2_MUCL39482 cds-NP_012723.3_MUCL39482 98.0 99.5 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:70177-72159:- gene-YKL198C_MUCL42920 rna-NM_001179764.2_MUCL42920 cds-NP_012723.3_MUCL42920 98.0 99.5 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:68221-70209:- gene-YKL198C_NCIM3186 rna-NM_001179764.2_NCIM3186 cds-NP_012723.3_NCIM3186 98.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:66663-68645:- gene-YKL198C_NCYC1407 rna-NM_001179764.2_NCYC1407 cds-NP_012723.3_NCYC1407 98.1 99.5 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:74173-76164:- gene-YKL198C_PE2H3 rna-NM_001179764.2_PE2H3 cds-NP_012723.3_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:70467-72458:- gene-YKL198C_PE2H4 rna-NM_001179764.2_PE2H4 cds-NP_012723.3_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:68232-70220:- gene-YKL198C_S288C rna-NM_001179764.2_S288C cds-NP_012723.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000113.1:2102-4093:- gene-YKL198C_SA1 rna-NM_001179764.2_SA1 cds-NP_012723.3_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:66836-68818:- gene-YKL198C_ThermosaccDry rna-NM_001179764.2_ThermosaccDry cds-NP_012723.3_ThermosaccDry 98.0 99.5 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:65879-67870:- gene-YKL198C_VR1 rna-NM_001179764.2_VR1 cds-NP_012723.3_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:65757-67739:- gene-YKL198C_ZTW1 rna-NM_001179764.2_ZTW1 cds-NP_012723.3_ZTW1 98.0 99.5 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:74427-76396:- gene-YKL198C_Sparadoxus rna-NM_001179764.2_Sparadoxus cds-NP_012723.3_Sparadoxus 87.1 98.8 Verified 1 1 0 False False False True False

Additional files