PTH2 (YBL057C)


Gene profile

Gene name: PTH2
Reference locus (S288C): YBL057C
Gene biotype: protein_coding

Description: Peptidyl-trna hydrolase, pth2 family; Peptidyl-tRNA hydrolase 2; One of two mitochondrially-localized peptidyl-tRNA hydrolases; negatively regulates the ubiquitin-proteasome pathway via interactions with ubiquitin-like ubiquitin-associated proteins; dispensable for cell growth; see also PTH1

Top 10 interactors (score): DSK2 (0.915); IRC22 (0.827); PTH1 (0.818); ERB1 (0.706); NIT3 (0.7); MSD1 (0.696); SEC11 (0.692); TPC1 (0.676); PTH4 (0.675); CBR1 (0.655); AIM11 (0.652); MIC26 (0.618); CCT4 (0.592); RAD23 (0.57); TCD2 (0.569); BOL1 (0.568); SCM4 (0.562); UFD2 (0.539); UTP6 (0.508); ADP1 (0.497)

Homologues (species, bitscore): PTRH2 (Homo sapiens, 131.0); Ptrh2 (Mus musculus, 123.2); ptrh2 (Danio rerio, 122.1); ptrh2 (Xenopus tropicalis, 124.4); CG1307 (Drosophila melanogaster, 91.3); C24G6.8 (Caenorhabditis elegans, 70.9); AT4G32900 (Arabidopsis thaliana, 107.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:106385-107011:- gene-YBL057C_AKU4011 rna-NM_001178297.2_AKU4011 cds-NP_009496.2_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:97238-97864:- gene-YBL057C_BG1 rna-NM_001178297.2_BG1 cds-NP_009496.2_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:106999-107625:- gene-YBL057C_Bruggeman rna-NM_001178297.2_Bruggeman cds-NP_009496.2_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:109637-110263:- gene-YBL057C_CAT1 rna-NM_001178297.2_CAT1 cds-NP_009496.2_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:98952-99578:- gene-YBL057C_CBS1585 rna-NM_001178297.2_CBS1585 cds-NP_009496.2_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:107458-108084:- gene-YBL057C_CBS436 rna-NM_001178297.2_CBS436 cds-NP_009496.2_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:97458-98084:- gene-YBL057C_CBS6412 rna-NM_001178297.2_CBS6412 cds-NP_009496.2_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:104530-105156:- gene-YBL057C_CBS6413 rna-NM_001178297.2_CBS6413 cds-NP_009496.2_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:106562-107188:- gene-YBL057C_CENPK1137D rna-NM_001178297.2_CENPK1137D cds-NP_009496.2_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:120384-121010:- gene-YBL057C_EthanolRed rna-NM_001178297.2_EthanolRed cds-NP_009496.2_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:121237-121863:- gene-YBL057C_FaliES1 rna-NM_001178297.2_FaliES1 cds-NP_009496.2_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000072.1:23852-24478:- gene-YBL057C_JAY291 rna-NM_001178297.2_JAY291 cds-NP_009496.2_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:106373-106999:- gene-YBL057C_MUCL30387 rna-NM_001178297.2_MUCL30387 cds-NP_009496.2_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:107652-108278:- gene-YBL057C_MUCL30388 rna-NM_001178297.2_MUCL30388 cds-NP_009496.2_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:99133-99759:- gene-YBL057C_MUCL39482 rna-NM_001178297.2_MUCL39482 cds-NP_009496.2_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:105966-106592:- gene-YBL057C_MUCL42920 rna-NM_001178297.2_MUCL42920 cds-NP_009496.2_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:112598-113224:- gene-YBL057C_NCIM3186 rna-NM_001178297.2_NCIM3186 cds-NP_009496.2_NCIM3186 99.8 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:100275-100901:- gene-YBL057C_NCYC1407 rna-NM_001178297.2_NCYC1407 cds-NP_009496.2_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:106528-107154:- gene-YBL057C_PE2H3 rna-NM_001178297.2_PE2H3 cds-NP_009496.2_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:104172-104798:- gene-YBL057C_PE2H4 rna-NM_001178297.2_PE2H4 cds-NP_009496.2_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:112801-113427:- gene-YBL057C_S288C rna-NM_001178297.2_S288C cds-NP_009496.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:96907-97533:- gene-YBL057C_SA1 rna-NM_001178297.2_SA1 cds-NP_009496.2_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:121198-121824:- gene-YBL057C_ThermosaccDry rna-NM_001178297.2_ThermosaccDry cds-NP_009496.2_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:103362-103988:- gene-YBL057C_VR1 rna-NM_001178297.2_VR1 cds-NP_009496.2_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:97914-98540:- gene-YBL057C_ZTW1 rna-NM_001178297.2_ZTW1 cds-NP_009496.2_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:132577-133201:- gene-YBL057C_Sparadoxus rna-NM_001178297.2_Sparadoxus cds-NP_009496.2_Sparadoxus 87.8 99.5 Verified 1 1 0 False False True False False

Additional files