PTC7 (YHR076W)


Gene profile

Gene name: PTC7
Reference locus (S288C): YHR076W
Gene biotype: protein_coding

Description: Type 2C serine/threonine protein phosphatase (PP2C); alternatively spliced to create two mRNA isoforms; protein from spliced form localizes to the mitochondria while the one from the unspliced form is localized to the nuclear envelope; activates coenzyme Q6 biosynthesis by dephosphorylation of demethoxy-Q6 hydroxylase Coq7p

Top 10 interactors (score): PTC5 (0.987); PTC6 (0.973); PTC1 (0.9); PTC2 (0.898); PTC4 (0.878); PTC3 (0.866); CAT5 (0.85); SEC14 (0.781); TIM50 (0.744); KDX1 (0.702); UBC6 (0.694); ENV7 (0.689); HAS1 (0.68); PPT1 (0.671); LOS1 (0.66); SEC5 (0.647); PDA1 (0.636); PPQ1 (0.624); YCH1 (0.622); PPZ2 (0.619)

Homologues (species, bitscore): PPTC7 (Homo sapiens, 119.8); Pptc7 (Mus musculus, 120.2); pptc7a (Danio rerio, 117.1); pptc7 (Xenopus tropicalis, 120.2); CG15035 (Drosophila melanogaster, 113.2); W09D10.4 (Caenorhabditis elegans, 104.4); AT4G16580 (Arabidopsis thaliana, 97.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:237521-238645:+ gene-YHR076W_AKU4011 rna-NM_001179206.1_AKU4011 cds-NP_011943.2_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:157868-158992:+ gene-YHR076W_BG1 rna-NM_001179206.1_BG1 cds-NP_011943.2_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:245348-246472:+ gene-YHR076W_Bruggeman rna-NM_001179206.1_Bruggeman cds-NP_011943.2_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:240242-241366:+ gene-YHR076W_CAT1 rna-NM_001179206.1_CAT1 cds-NP_011943.2_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:236562-237686:+ gene-YHR076W_CBS1585 rna-NM_001179206.1_CBS1585 cds-NP_011943.2_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:234421-235545:+ gene-YHR076W_CBS436 rna-NM_001179206.1_CBS436 cds-NP_011943.2_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:239907-241031:+ gene-YHR076W_CBS6412 rna-NM_001179206.1_CBS6412 cds-NP_011943.2_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:237602-238726:+ gene-YHR076W_CBS6413 rna-NM_001179206.1_CBS6413 cds-NP_011943.2_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:244271-245395:+ gene-YHR076W_CENPK1137D rna-NM_001179206.1_CENPK1137D cds-NP_011943.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:297119-298243:+ gene-YHR076W_EthanolRed rna-NM_001179206.1_EthanolRed cds-NP_011943.2_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:237923-239047:+ gene-YHR076W_FaliES1 rna-NM_001179206.1_FaliES1 cds-NP_011943.2_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000394.1:20663-21787:+ gene-YHR076W_JAY291 rna-NM_001179206.1_JAY291 cds-NP_011943.2_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:244860-245984:+ gene-YHR076W_MUCL30387 rna-NM_001179206.1_MUCL30387 cds-NP_011943.2_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:244726-245850:+ gene-YHR076W_MUCL30388 rna-NM_001179206.1_MUCL30388 cds-NP_011943.2_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:236886-238010:+ gene-YHR076W_MUCL39482 rna-NM_001179206.1_MUCL39482 cds-NP_011943.2_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:243625-244749:+ gene-YHR076W_MUCL42920 rna-NM_001179206.1_MUCL42920 cds-NP_011943.2_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:250983-252107:+ gene-YHR076W_NCIM3186 rna-NM_001179206.1_NCIM3186 cds-NP_011943.2_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:239350-240474:+ gene-YHR076W_NCYC1407 rna-NM_001179206.1_NCYC1407 cds-NP_011943.2_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:239027-240151:+ gene-YHR076W_PE2H3 rna-NM_001179206.1_PE2H3 cds-NP_011943.2_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:246474-247598:+ gene-YHR076W_PE2H4 rna-NM_001179206.1_PE2H4 cds-NP_011943.2_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:251101-252225:+ gene-YHR076W_S288C rna-NM_001179206.1_S288C cds-NP_011943.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000014.1:106758-107882:- gene-YHR076W_SA1 rna-NM_001179206.1_SA1 cds-NP_011943.2_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:239014-240138:+ gene-YHR076W_ThermosaccDry rna-NM_001179206.1_ThermosaccDry cds-NP_011943.2_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:246902-248026:+ gene-YHR076W_VR1 rna-NM_001179206.1_VR1 cds-NP_011943.2_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:230565-231689:+ gene-YHR076W_ZTW1 rna-NM_001179206.1_ZTW1 cds-NP_011943.2_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:236310-237434:+ gene-YHR076W_Sparadoxus rna-NM_001179206.1_Sparadoxus cds-NP_011943.2_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files