Gene name: PTC6
Reference locus (S288C): YCR079W
Gene biotype: protein_coding
Description: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; Mitochondrial type 2C protein phosphatase (PP2C); has similarity to mammalian PP1Ks; involved in mitophagy; null mutant is sensitive to rapamycin and has decreased phosphorylation of the Pda1 subunit of pyruvate dehydrogenase
Top 10 interactors (score): PTC5 (0.991); PTC7 (0.973); PTC1 (0.933); PDA1 (0.909); PRO2 (0.882); UTH1 (0.836); PKP1 (0.825); PTC2 (0.795); PTC3 (0.777); PTC4 (0.762); PDB1 (0.758); RTG3 (0.757); ATG33 (0.752); MRPL50 (0.747); ATG32 (0.744); SDP1 (0.739); PKP2 (0.738); SIT4 (0.735); NBP2 (0.684); LAT1 (0.669)
Homologues (species, bitscore): PPM1K (Homo sapiens, 67.4); Ppm1k (Mus musculus, 71.6); si:ch211-149b19.3 (Danio rerio, 68.9); ppm1k (Xenopus tropicalis, 65.9); AT4G28400 (Arabidopsis thaliana, 55.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:247346-248674:+ | gene-YCR079W_AKU4011 | rna-NM_001180034.1_AKU4011 | cds-NP_010003.2_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000067.1:106002-107330:+ | gene-YCR079W_BG1 | rna-NM_001180034.1_BG1 | cds-NP_010003.2_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:243557-244885:+ | gene-YCR079W_Bruggeman | rna-NM_001180034.1_Bruggeman | cds-NP_010003.2_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:254607-255935:+ | gene-YCR079W_CAT1 | rna-NM_001180034.1_CAT1 | cds-NP_010003.2_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:242161-243489:+ | gene-YCR079W_CBS1585 | rna-NM_001180034.1_CBS1585 | cds-NP_010003.2_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:253942-255270:+ | gene-YCR079W_CBS436 | rna-NM_001180034.1_CBS436 | cds-NP_010003.2_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:233863-235191:+ | gene-YCR079W_CBS6412 | rna-NM_001180034.1_CBS6412 | cds-NP_010003.2_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:248211-249539:+ | gene-YCR079W_CBS6413 | rna-NM_001180034.1_CBS6413 | cds-NP_010003.2_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:252044-253372:+ | gene-YCR079W_CENPK1137D | rna-NM_001180034.1_CENPK1137D | cds-NP_010003.2_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:243161-244489:+ | gene-YCR079W_EthanolRed | rna-NM_001180034.1_EthanolRed | cds-NP_010003.2_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:248524-249852:+ | gene-YCR079W_FaliES1 | rna-NM_001180034.1_FaliES1 | cds-NP_010003.2_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000323.1:38938-40266:- | gene-YCR079W_JAY291 | rna-NM_001180034.1_JAY291 | cds-NP_010003.2_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:240685-242013:+ | gene-YCR079W_MUCL30387 | rna-NM_001180034.1_MUCL30387 | cds-NP_010003.2_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:240552-241880:+ | gene-YCR079W_MUCL30388 | rna-NM_001180034.1_MUCL30388 | cds-NP_010003.2_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:248725-250053:+ | gene-YCR079W_MUCL39482 | rna-NM_001180034.1_MUCL39482 | cds-NP_010003.2_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:245131-246459:+ | gene-YCR079W_MUCL42920 | rna-NM_001180034.1_MUCL42920 | cds-NP_010003.2_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:252477-253805:+ | gene-YCR079W_NCIM3186 | rna-NM_001180034.1_NCIM3186 | cds-NP_010003.2_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:249564-250892:+ | gene-YCR079W_NCYC1407 | rna-NM_001180034.1_NCYC1407 | cds-NP_010003.2_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:264119-265447:+ | gene-YCR079W_PE2H3 | rna-NM_001180034.1_PE2H3 | cds-NP_010003.2_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:252673-254001:+ | gene-YCR079W_PE2H4 | rna-NM_001180034.1_PE2H4 | cds-NP_010003.2_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:252845-254173:+ | gene-YCR079W_S288C | rna-NM_001180034.1_S288C | cds-NP_010003.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000044.1:52694-54022:+ | gene-YCR079W_SA1 | rna-NM_001180034.1_SA1 | cds-NP_010003.2_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:248451-249779:+ | gene-YCR079W_ThermosaccDry | rna-NM_001180034.1_ThermosaccDry | cds-NP_010003.2_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:259661-260989:+ | gene-YCR079W_VR1 | rna-NM_001180034.1_VR1 | cds-NP_010003.2_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:246306-247634:+ | gene-YCR079W_ZTW1 | rna-NM_001180034.1_ZTW1 | cds-NP_010003.2_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:280445-281773:+ | gene-YCR079W_Sparadoxus | rna-NM_001180034.1_Sparadoxus | cds-NP_010003.2_Sparadoxus | 90.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |