Gene name: PTC5
Reference locus (S288C): YOR090C
Gene biotype: protein_coding
Description: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; Mitochondrial type 2C protein phosphatase (PP2C); involved in regulation of pyruvate dehydrogenase activity by dephosphorylating the serine 133 of the Pda1p subunit; localizes to the intermembrane space and is imported via the presequence pathway and processed by the inner membrane protease (Imp1p-Imp2p); acts in concert with kinases Pkp1p and Pkp2p and phosphatase Ptc6p
Top 10 interactors (score): PTC6 (0.991); PTC7 (0.987); PDA1 (0.961); PTC1 (0.887); PKP1 (0.863); PKP2 (0.816); TIM50 (0.798); SDP1 (0.796); PDB1 (0.783); PSR1 (0.782); YOR283W (0.762); PTP1 (0.754); CMP2 (0.738); PPZ1 (0.734); DET1 (0.714); MIX23 (0.694); YMR196W (0.682); YCH1 (0.682); PSR2 (0.681); LAT1 (0.68)
Homologues (species, bitscore): PDP2 (Homo sapiens, 157.9); Pdp2 (Mus musculus, 164.5); pdp1 (Danio rerio, 152.5); pdp2 (Xenopus tropicalis, 167.5); Pdp (Drosophila melanogaster, 171.4); pdp-1 (Caenorhabditis elegans, 153.7); AT3G55050 (Arabidopsis thaliana, 99.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:475474-477192:- | gene-YOR090C_AKU4011 | rna-NM_001183509.1_AKU4011 | cds-NP_014733.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:102139-103857:+ | gene-YOR090C_BG1 | rna-NM_001183509.1_BG1 | cds-NP_014733.1_BG1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:478783-480501:- | gene-YOR090C_Bruggeman | rna-NM_001183509.1_Bruggeman | cds-NP_014733.1_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:477317-479284:- | gene-YOR090C_CAT1 | rna-NM_001183509.1_CAT1 | cds-NP_014733.1_CAT1 | 86.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:470766-472484:- | gene-YOR090C_CBS1585 | rna-NM_001183509.1_CBS1585 | cds-NP_014733.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:475518-477236:- | gene-YOR090C_CBS436 | rna-NM_001183509.1_CBS436 | cds-NP_014733.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:469507-471225:- | gene-YOR090C_CBS6412 | rna-NM_001183509.1_CBS6412 | cds-NP_014733.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:476802-478520:- | gene-YOR090C_CBS6413 | rna-NM_001183509.1_CBS6413 | cds-NP_014733.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:491168-492886:- | gene-YOR090C_CENPK1137D | rna-NM_001183509.1_CENPK1137D | cds-NP_014733.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:472005-473723:- | gene-YOR090C_EthanolRed | rna-NM_001183509.1_EthanolRed | cds-NP_014733.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:475514-477232:- | gene-YOR090C_FaliES1 | rna-NM_001183509.1_FaliES1 | cds-NP_014733.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000063.1:82286-84004:+ | gene-YOR090C_JAY291 | rna-NM_001183509.1_JAY291 | cds-NP_014733.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:483319-485037:- | gene-YOR090C_MUCL30387 | rna-NM_001183509.1_MUCL30387 | cds-NP_014733.1_MUCL30387 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:488073-489791:- | gene-YOR090C_MUCL30388 | rna-NM_001183509.1_MUCL30388 | cds-NP_014733.1_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:478402-480120:- | gene-YOR090C_MUCL39482 | rna-NM_001183509.1_MUCL39482 | cds-NP_014733.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:494225-495943:- | gene-YOR090C_MUCL42920 | rna-NM_001183509.1_MUCL42920 | cds-NP_014733.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:491012-492730:- | gene-YOR090C_NCIM3186 | rna-NM_001183509.1_NCIM3186 | cds-NP_014733.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:484583-486301:- | gene-YOR090C_NCYC1407 | rna-NM_001183509.1_NCYC1407 | cds-NP_014733.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:483591-485309:- | gene-YOR090C_PE2H3 | rna-NM_001183509.1_PE2H3 | cds-NP_014733.1_PE2H3 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:493967-495685:- | gene-YOR090C_PE2H4 | rna-NM_001183509.1_PE2H4 | cds-NP_014733.1_PE2H4 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:491123-492841:- | gene-YOR090C_S288C | rna-NM_001183509.1_S288C | cds-NP_014733.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000098.1:29969-31687:+ | gene-YOR090C_SA1 | rna-NM_001183509.1_SA1 | cds-NP_014733.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:474668-476386:- | gene-YOR090C_ThermosaccDry | rna-NM_001183509.1_ThermosaccDry | cds-NP_014733.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:476511-478229:- | gene-YOR090C_VR1 | rna-NM_001183509.1_VR1 | cds-NP_014733.1_VR1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:208662-210380:- | gene-YOR090C_ZTW1 | rna-NM_001183509.1_ZTW1 | cds-NP_014733.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:480448-482166:- | gene-YOR090C_Sparadoxus | rna-NM_001183509.1_Sparadoxus | cds-NP_014733.1_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |