Gene name: PTC4
Reference locus (S288C): YBR125C
Gene biotype: protein_coding
Description: Cytoplasmic type 2C protein phosphatase (PP2C); identified as a high-copy number suppressor of cnb1 mpk1 synthetic lethality; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity
Top 10 interactors (score): PAA1 (0.916); PTC7 (0.878); HOG1 (0.823); SLT2 (0.797); SND1 (0.792); PTC6 (0.762); VHS1 (0.76); MRPL50 (0.745); YVH1 (0.74); MSG5 (0.676); SDP1 (0.674); PPZ1 (0.663); KDX1 (0.657); STE11 (0.624); PPQ1 (0.622); YDL012C (0.617); BCK1 (0.606); PKP2 (0.603); FUS3 (0.602); PKP1 (0.598)
Homologues (species, bitscore): PPM1G (Homo sapiens, 126.3); Ppm1g (Mus musculus, 127.5); ppm1aa (Danio rerio, 124.0); ppm1b (Xenopus tropicalis, 121.7); CG10417 (Drosophila melanogaster, 137.9); T23F11.1 (Caenorhabditis elegans, 136.3); AT2G25070 (Arabidopsis thaliana, 150.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:470093-471274:- | gene-YBR125C_AKU4011 | rna-NM_001178473.1_AKU4011 | cds-NP_009683.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:460639-461820:- | gene-YBR125C_BG1 | rna-NM_001178473.1_BG1 | cds-NP_009683.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:471871-473052:- | gene-YBR125C_Bruggeman | rna-NM_001178473.1_Bruggeman | cds-NP_009683.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:475042-476223:- | gene-YBR125C_CAT1 | rna-NM_001178473.1_CAT1 | cds-NP_009683.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:461877-463058:- | gene-YBR125C_CBS1585 | rna-NM_001178473.1_CBS1585 | cds-NP_009683.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:469954-471135:- | gene-YBR125C_CBS436 | rna-NM_001178473.1_CBS436 | cds-NP_009683.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:559740-560921:- | gene-YBR125C_CBS6412 | rna-NM_001178473.1_CBS6412 | cds-NP_009683.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:467505-468686:- | gene-YBR125C_CBS6413 | rna-NM_001178473.1_CBS6413 | cds-NP_009683.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:480970-482151:- | gene-YBR125C_CENPK1137D | rna-NM_001178473.1_CENPK1137D | cds-NP_009683.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:596115-597296:- | gene-YBR125C_EthanolRed | rna-NM_001178473.1_EthanolRed | cds-NP_009683.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:486132-487313:- | gene-YBR125C_FaliES1 | rna-NM_001178473.1_FaliES1 | cds-NP_009683.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000444.1:9541-10722:- | gene-YBR125C_JAY291 | rna-NM_001178473.1_JAY291 | cds-NP_009683.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:474776-475957:- | gene-YBR125C_MUCL30387 | rna-NM_001178473.1_MUCL30387 | cds-NP_009683.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:473135-474316:- | gene-YBR125C_MUCL30388 | rna-NM_001178473.1_MUCL30388 | cds-NP_009683.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:460270-461451:- | gene-YBR125C_MUCL39482 | rna-NM_001178473.1_MUCL39482 | cds-NP_009683.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:470190-471371:- | gene-YBR125C_MUCL42920 | rna-NM_001178473.1_MUCL42920 | cds-NP_009683.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:486996-488177:- | gene-YBR125C_NCIM3186 | rna-NM_001178473.1_NCIM3186 | cds-NP_009683.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:462798-463979:- | gene-YBR125C_NCYC1407 | rna-NM_001178473.1_NCYC1407 | cds-NP_009683.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:475380-476561:- | gene-YBR125C_PE2H3 | rna-NM_001178473.1_PE2H3 | cds-NP_009683.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:473056-474237:- | gene-YBR125C_PE2H4 | rna-NM_001178473.1_PE2H4 | cds-NP_009683.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:487199-488380:- | gene-YBR125C_S288C | rna-NM_001178473.1_S288C | cds-NP_009683.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000032.1:8316-9497:- | gene-YBR125C_SA1 | rna-NM_001178473.1_SA1 | cds-NP_009683.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:485139-486320:- | gene-YBR125C_ThermosaccDry | rna-NM_001178473.1_ThermosaccDry | cds-NP_009683.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:466637-467818:- | gene-YBR125C_VR1 | rna-NM_001178473.1_VR1 | cds-NP_009683.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:460286-461467:- | gene-YBR125C_ZTW1 | rna-NM_001178473.1_ZTW1 | cds-NP_009683.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:497507-498688:- | gene-YBR125C_Sparadoxus | rna-NM_001178473.1_Sparadoxus | cds-NP_009683.1_Sparadoxus | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |