Gene name: PTC3
Reference locus (S288C): YBL056W
Gene biotype: protein_coding
Description: Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA damage checkpoint inactivation; PTC3 has a paralog, PTC2, that arose from the whole genome duplication
Top 10 interactors (score): PBS2 (0.893); PAA1 (0.884); HOG1 (0.87); PTC7 (0.866); PPH3 (0.854); PTP2 (0.853); PTP3 (0.844); PTC2 (0.782); PTC6 (0.777); NBP2 (0.773); SLN1 (0.765); SLT2 (0.715); IDS2 (0.678); VPS15 (0.676); PTP1 (0.667); PSY2 (0.638); STE11 (0.633); SSK22 (0.619); TSR1 (0.618); YPD1 (0.585)
Homologues (species, bitscore): PPM1B (Homo sapiens, 167.9); Ppm1b (Mus musculus, 166.8); ppm1bb (Danio rerio, 177.9); ppm1b (Xenopus tropicalis, 172.6); Ppm1 (Drosophila melanogaster, 227.6); T23F11.1 (Caenorhabditis elegans, 243.0); AT2G25070 (Arabidopsis thaliana, 213.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:107346-108752:+ | gene-YBL056W_AKU4011 | rna-NM_001178296.2_AKU4011 | cds-NP_009497.2_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:98199-99605:+ | gene-YBL056W_BG1 | rna-NM_001178296.2_BG1 | cds-NP_009497.2_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:107960-109366:+ | gene-YBL056W_Bruggeman | rna-NM_001178296.2_Bruggeman | cds-NP_009497.2_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:110598-112004:+ | gene-YBL056W_CAT1 | rna-NM_001178296.2_CAT1 | cds-NP_009497.2_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:99913-101319:+ | gene-YBL056W_CBS1585 | rna-NM_001178296.2_CBS1585 | cds-NP_009497.2_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:108419-109825:+ | gene-YBL056W_CBS436 | rna-NM_001178296.2_CBS436 | cds-NP_009497.2_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:98419-99825:+ | gene-YBL056W_CBS6412 | rna-NM_001178296.2_CBS6412 | cds-NP_009497.2_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:105491-106897:+ | gene-YBL056W_CBS6413 | rna-NM_001178296.2_CBS6413 | cds-NP_009497.2_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:107523-108929:+ | gene-YBL056W_CENPK1137D | rna-NM_001178296.2_CENPK1137D | cds-NP_009497.2_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:121345-122751:+ | gene-YBL056W_EthanolRed | rna-NM_001178296.2_EthanolRed | cds-NP_009497.2_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:122198-123604:+ | gene-YBL056W_FaliES1 | rna-NM_001178296.2_FaliES1 | cds-NP_009497.2_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000072.1:24813-26219:+ | gene-YBL056W_JAY291 | rna-NM_001178296.2_JAY291 | cds-NP_009497.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:107334-108740:+ | gene-YBL056W_MUCL30387 | rna-NM_001178296.2_MUCL30387 | cds-NP_009497.2_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:108613-110019:+ | gene-YBL056W_MUCL30388 | rna-NM_001178296.2_MUCL30388 | cds-NP_009497.2_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:100094-101500:+ | gene-YBL056W_MUCL39482 | rna-NM_001178296.2_MUCL39482 | cds-NP_009497.2_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:106927-108333:+ | gene-YBL056W_MUCL42920 | rna-NM_001178296.2_MUCL42920 | cds-NP_009497.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:113559-114965:+ | gene-YBL056W_NCIM3186 | rna-NM_001178296.2_NCIM3186 | cds-NP_009497.2_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:101236-102642:+ | gene-YBL056W_NCYC1407 | rna-NM_001178296.2_NCYC1407 | cds-NP_009497.2_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:107489-108895:+ | gene-YBL056W_PE2H3 | rna-NM_001178296.2_PE2H3 | cds-NP_009497.2_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:105133-106539:+ | gene-YBL056W_PE2H4 | rna-NM_001178296.2_PE2H4 | cds-NP_009497.2_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:113762-115168:+ | gene-YBL056W_S288C | rna-NM_001178296.2_S288C | cds-NP_009497.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:97868-99274:+ | gene-YBL056W_SA1 | rna-NM_001178296.2_SA1 | cds-NP_009497.2_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:122159-123565:+ | gene-YBL056W_ThermosaccDry | rna-NM_001178296.2_ThermosaccDry | cds-NP_009497.2_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:104323-105729:+ | gene-YBL056W_VR1 | rna-NM_001178296.2_VR1 | cds-NP_009497.2_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:98875-100281:+ | gene-YBL056W_ZTW1 | rna-NM_001178296.2_ZTW1 | cds-NP_009497.2_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:133536-134942:+ | gene-YBL056W_Sparadoxus | rna-NM_001178296.2_Sparadoxus | cds-NP_009497.2_Sparadoxus | 93.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |