Gene name: PTC1
Reference locus (S288C): YDL006W
Gene biotype: protein_coding
Description: Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p, inactivating osmosensing MAPK cascade; involved in Fus3p activation during pheromone response; deletion affects precursor tRNA splicing, mitochondrial inheritance, and sporulation; Belongs to the PP2C family
Top 10 interactors (score): NBP2 (0.999); HOG1 (0.997); PBS2 (0.994); PTP2 (0.982); BCK1 (0.956); SLT2 (0.948); PTC6 (0.933); MKK1 (0.93); PTP3 (0.91); PTC7 (0.9); STE5 (0.899); PTC5 (0.887); PTP1 (0.874); FUS3 (0.867); YPD1 (0.853); PKC1 (0.851); SSK2 (0.845); SLN1 (0.844); SIT4 (0.844); MSG5 (0.835)
Homologues (species, bitscore): PPM1B (Homo sapiens, 139.0); Ppm1a (Mus musculus, 139.4); ppm1na (Danio rerio, 149.1); ppm1b (Xenopus tropicalis, 140.2); CG6036 (Drosophila melanogaster, 143.7); T23F11.1 (Caenorhabditis elegans, 114.8); AT5G24940 (Arabidopsis thaliana, 148.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:425165-426010:+ | gene-YDL006W_AKU4011 | rna-NM_001180065.3_AKU4011 | cds-NP_010278.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:123400-124245:- | gene-YDL006W_BG1 | rna-NM_001180065.3_BG1 | cds-NP_010278.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:445764-446609:+ | gene-YDL006W_Bruggeman | rna-NM_001180065.3_Bruggeman | cds-NP_010278.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:438611-439456:+ | gene-YDL006W_CAT1 | rna-NM_001180065.3_CAT1 | cds-NP_010278.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:422376-423221:+ | gene-YDL006W_CBS1585 | rna-NM_001180065.3_CBS1585 | cds-NP_010278.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:439139-439984:+ | gene-YDL006W_CBS436 | rna-NM_001180065.3_CBS436 | cds-NP_010278.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:419624-420469:+ | gene-YDL006W_CBS6412 | rna-NM_001180065.3_CBS6412 | cds-NP_010278.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:441314-442159:+ | gene-YDL006W_CBS6413 | rna-NM_001180065.3_CBS6413 | cds-NP_010278.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:438772-439617:+ | gene-YDL006W_CENPK1137D | rna-NM_001180065.3_CENPK1137D | cds-NP_010278.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:433998-434843:+ | gene-YDL006W_EthanolRed | rna-NM_001180065.3_EthanolRed | cds-NP_010278.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:440166-441011:+ | gene-YDL006W_FaliES1 | rna-NM_001180065.3_FaliES1 | cds-NP_010278.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000442.1:31029-31874:- | gene-YDL006W_JAY291 | rna-NM_001180065.3_JAY291 | cds-NP_010278.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:439635-440480:+ | gene-YDL006W_MUCL30387 | rna-NM_001180065.3_MUCL30387 | cds-NP_010278.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:430097-430942:+ | gene-YDL006W_MUCL30388 | rna-NM_001180065.3_MUCL30388 | cds-NP_010278.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:423745-424590:+ | gene-YDL006W_MUCL39482 | rna-NM_001180065.3_MUCL39482 | cds-NP_010278.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:345170-346015:+ | gene-YDL006W_MUCL42920 | rna-NM_001180065.3_MUCL42920 | cds-NP_010278.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:439832-440677:+ | gene-YDL006W_NCIM3186 | rna-NM_001180065.3_NCIM3186 | cds-NP_010278.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:422667-423512:+ | gene-YDL006W_NCYC1407 | rna-NM_001180065.3_NCYC1407 | cds-NP_010278.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:438243-439088:+ | gene-YDL006W_PE2H3 | rna-NM_001180065.3_PE2H3 | cds-NP_010278.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:437602-438447:+ | gene-YDL006W_PE2H4 | rna-NM_001180065.3_PE2H4 | cds-NP_010278.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:439909-440754:+ | gene-YDL006W_S288C | rna-NM_001180065.3_S288C | cds-NP_010278.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000099.1:31218-32063:- | gene-YDL006W_SA1 | rna-NM_001180065.3_SA1 | cds-NP_010278.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:439646-440491:+ | gene-YDL006W_ThermosaccDry | rna-NM_001180065.3_ThermosaccDry | cds-NP_010278.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:444100-444945:+ | gene-YDL006W_VR1 | rna-NM_001180065.3_VR1 | cds-NP_010278.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:437540-438385:+ | gene-YDL006W_ZTW1 | rna-NM_001180065.3_ZTW1 | cds-NP_010278.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:441931-442776:+ | gene-YDL006W_Sparadoxus | rna-NM_001180065.3_Sparadoxus | cds-NP_010278.3_Sparadoxus | 92.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |