Gene name: PSY3
Reference locus (S288C): YLR376C
Gene biotype: protein_coding
Description: Platinum sensitivity protein 3; Component of Shu complex (aka PCSS complex); Shu complex also includes Shu1, Csm2, Shu2, and promotes error-free DNA repair; promotes Rad51p filament assembly; Shu complex mediates inhibition of Srs2p function; Psy3p and Csm2p contain similar DNA-binding regions which work together to form a single DNA binding site; deletion of PSY3 results in a mutator phenotype; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C
Top 10 interactors (score): SHU1 (0.999); SHU2 (0.999); CSM2 (0.999); RAD2 (0.929); SRS2 (0.919); RAD4 (0.912); ABF1 (0.9); TFB1 (0.9); SSL2 (0.9); RAD23 (0.9); SSL1 (0.9); RAD16 (0.9); RAD7 (0.9); RAD3 (0.9); SGS1 (0.897); RAD51 (0.891); RAD55 (0.866); RAD52 (0.855); RAD57 (0.823); RAD14 (0.819)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:822362-823090:- | gene-YLR376C_AKU4011 | rna-NM_001182265.1_AKU4011 | cds-NP_013480.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:54513-55241:- | gene-YLR376C_BG1 | rna-NM_001182265.1_BG1 | cds-NP_013480.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:860696-861424:- | gene-YLR376C_Bruggeman | rna-NM_001182265.1_Bruggeman | cds-NP_013480.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:856188-856916:- | gene-YLR376C_CAT1 | rna-NM_001182265.1_CAT1 | cds-NP_013480.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:857352-858080:- | gene-YLR376C_CBS1585 | rna-NM_001182265.1_CBS1585 | cds-NP_013480.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:841595-842323:- | gene-YLR376C_CBS436 | rna-NM_001182265.1_CBS436 | cds-NP_013480.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:894374-895102:- | gene-YLR376C_CBS6412 | rna-NM_001182265.1_CBS6412 | cds-NP_013480.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:858245-858973:- | gene-YLR376C_CBS6413 | rna-NM_001182265.1_CBS6413 | cds-NP_013480.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:857598-858326:- | gene-YLR376C_CENPK1137D | rna-NM_001182265.1_CENPK1137D | cds-NP_013480.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:814943-815671:- | gene-YLR376C_EthanolRed | rna-NM_001182265.1_EthanolRed | cds-NP_013480.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:843748-844476:- | gene-YLR376C_FaliES1 | rna-NM_001182265.1_FaliES1 | cds-NP_013480.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000161.1:54332-55060:- | gene-YLR376C_JAY291 | rna-NM_001182265.1_JAY291 | cds-NP_013480.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:858101-858829:- | gene-YLR376C_MUCL30387 | rna-NM_001182265.1_MUCL30387 | cds-NP_013480.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:863730-864458:- | gene-YLR376C_MUCL30388 | rna-NM_001182265.1_MUCL30388 | cds-NP_013480.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:858571-859299:- | gene-YLR376C_MUCL39482 | rna-NM_001182265.1_MUCL39482 | cds-NP_013480.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:853868-854596:- | gene-YLR376C_MUCL42920 | rna-NM_001182265.1_MUCL42920 | cds-NP_013480.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:872800-873528:- | gene-YLR376C_NCIM3186 | rna-NM_001182265.1_NCIM3186 | cds-NP_013480.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:867793-868521:- | gene-YLR376C_NCYC1407 | rna-NM_001182265.1_NCYC1407 | cds-NP_013480.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:854751-855479:- | gene-YLR376C_PE2H3 | rna-NM_001182265.1_PE2H3 | cds-NP_013480.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:854495-855223:- | gene-YLR376C_PE2H4 | rna-NM_001182265.1_PE2H4 | cds-NP_013480.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:872826-873554:- | gene-YLR376C_S288C | rna-NM_001182265.1_S288C | cds-NP_013480.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:175138-175866:+ | gene-YLR376C_SA1 | rna-NM_001182265.1_SA1 | cds-NP_013480.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:846828-847556:- | gene-YLR376C_ThermosaccDry | rna-NM_001182265.1_ThermosaccDry | cds-NP_013480.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:859841-860569:- | gene-YLR376C_VR1 | rna-NM_001182265.1_VR1 | cds-NP_013480.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:184013-184741:- | gene-YLR376C_ZTW1 | rna-NM_001182265.1_ZTW1 | cds-NP_013480.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:832717-833445:- | gene-YLR376C_Sparadoxus | rna-NM_001182265.1_Sparadoxus | cds-NP_013480.1_Sparadoxus | 88.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |