PSY2 (YNL201C)


Gene profile

Gene name: PSY2
Reference locus (S288C): YNL201C
Gene biotype: protein_coding

Description: Subunit of protein phosphatase PP4 complex; Pph3p and Psy2p form the active complex, Psy4p may provide additional substrate specificity; regulates recovery from the DNA damage checkpoint, the gene conversion- and single-strand annealing-mediated pathways of meiotic double-strand break repair and efficient Non-Homologous End-Joining (NHEJ) pathway; Pph3p and Psy2p localize to foci on meiotic chromosomes; putative homolog of mammalian R3

Top 10 interactors (score): PSY4 (0.999); PPH3 (0.999); PPG1 (0.988); PPH21 (0.981); RAD53 (0.975); MEC1 (0.971); RRD1 (0.968); GLC7 (0.966); TPD3 (0.96); SIT4 (0.955); RRD2 (0.947); RFA2 (0.945); CDC55 (0.94); SDS22 (0.938); CMP2 (0.934); CNA1 (0.929); CNB1 (0.909); SPT5 (0.901); REG1 (0.9); GAC1 (0.9)

Homologues (species, bitscore): SMEK1 (Homo sapiens, 188.7); Smek1 (Mus musculus, 194.9); smek1 (Danio rerio, 181.0); ppp4r3a (Xenopus tropicalis, 188.0); flfl (Drosophila melanogaster, 178.7); smk-1 (Caenorhabditis elegans, 118.2); AT3G06670 (Arabidopsis thaliana, 132.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:254404-256980:- gene-YNL201C_AKU4011 rna-NM_001183039.1_AKU4011 cds-NP_014198.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:158355-160931:- gene-YNL201C_BG1 rna-NM_001183039.1_BG1 cds-NP_014198.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:264454-267030:- gene-YNL201C_Bruggeman rna-NM_001183039.1_Bruggeman cds-NP_014198.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:306696-309272:- gene-YNL201C_CAT1 rna-NM_001183039.1_CAT1 cds-NP_014198.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:255050-257626:- gene-YNL201C_CBS1585 rna-NM_001183039.1_CBS1585 cds-NP_014198.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:323339-325915:- gene-YNL201C_CBS436 rna-NM_001183039.1_CBS436 cds-NP_014198.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:250462-253038:- gene-YNL201C_CBS6412 rna-NM_001183039.1_CBS6412 cds-NP_014198.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:251483-254059:- gene-YNL201C_CBS6413 rna-NM_001183039.1_CBS6413 cds-NP_014198.1_CBS6413 99.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:254475-257051:- gene-YNL201C_CENPK1137D rna-NM_001183039.1_CENPK1137D cds-NP_014198.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:251372-253948:- gene-YNL201C_EthanolRed rna-NM_001183039.1_EthanolRed cds-NP_014198.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:247285-249861:- gene-YNL201C_FaliES1 rna-NM_001183039.1_FaliES1 cds-NP_014198.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000260.1:68503-71079:+ gene-YNL201C_JAY291 rna-NM_001183039.1_JAY291 cds-NP_014198.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:260240-262816:- gene-YNL201C_MUCL30387 rna-NM_001183039.1_MUCL30387 cds-NP_014198.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:294607-297183:- gene-YNL201C_MUCL30388 rna-NM_001183039.1_MUCL30388 cds-NP_014198.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:252289-254865:- gene-YNL201C_MUCL39482 rna-NM_001183039.1_MUCL39482 cds-NP_014198.1_MUCL39482 99.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:254656-257232:- gene-YNL201C_MUCL42920 rna-NM_001183039.1_MUCL42920 cds-NP_014198.1_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:260596-263172:- gene-YNL201C_NCIM3186 rna-NM_001183039.1_NCIM3186 cds-NP_014198.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:254379-256955:- gene-YNL201C_NCYC1407 rna-NM_001183039.1_NCYC1407 cds-NP_014198.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:251292-253868:- gene-YNL201C_PE2H3 rna-NM_001183039.1_PE2H3 cds-NP_014198.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:250680-253256:- gene-YNL201C_PE2H4 rna-NM_001183039.1_PE2H4 cds-NP_014198.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:260627-263203:- gene-YNL201C_S288C rna-NM_001183039.1_S288C cds-NP_014198.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000018.1:150395-152971:+ gene-YNL201C_SA1 rna-NM_001183039.1_SA1 cds-NP_014198.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:248142-250718:- gene-YNL201C_ThermosaccDry rna-NM_001183039.1_ThermosaccDry cds-NP_014198.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:266646-269222:- gene-YNL201C_VR1 rna-NM_001183039.1_VR1 cds-NP_014198.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:157975-160551:- gene-YNL201C_ZTW1 rna-NM_001183039.1_ZTW1 cds-NP_014198.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:258491-261067:- gene-YNL201C_Sparadoxus rna-NM_001183039.1_Sparadoxus cds-NP_014198.1_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files