PSO2 (YMR137C)


Gene profile

Gene name: PSO2
Reference locus (S288C): YMR137C
Gene biotype: protein_coding

Description: DNA cross-link repair protein PSO2/SNM1; Nuclease required for DNA single- and double-strand break repair; acts at a post-incision step in repair of breaks that result from interstrand cross-links produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation; forms nuclear foci upon DNA replication stress; Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family

Top 10 interactors (score): DNL4 (0.987); REV3 (0.975); YKU70 (0.956); YKU80 (0.941); MRE11 (0.941); EXO1 (0.936); RAD2 (0.912); MUS81 (0.908); MSH2 (0.9); RAD51 (0.894); RAD14 (0.887); RAD52 (0.88); PFA4 (0.861); RAD1 (0.85); RAD27 (0.849); POL4 (0.847); MPH1 (0.823); RAD9 (0.816); RAD6 (0.813); HRQ1 (0.813)

Homologues (species, bitscore): DCLRE1A (Homo sapiens, 176.8); Dclre1a (Mus musculus, 181.8); dclre1a (Danio rerio, 175.6); dclre1b (Xenopus tropicalis, 99.0); Snm1 (Drosophila melanogaster, 134.8); mrt-1 (Caenorhabditis elegans, 76.3); AT2G45700 (Arabidopsis thaliana, 167.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:582471-584456:- gene-YMR137C_AKU4011 rna-NM_001182639.1_AKU4011 cds-NP_013857.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000068.1:88071-90056:+ gene-YMR137C_BG1 rna-NM_001182639.1_BG1 cds-NP_013857.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:525658-527643:- gene-YMR137C_Bruggeman rna-NM_001182639.1_Bruggeman cds-NP_013857.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:527873-529858:- gene-YMR137C_CAT1 rna-NM_001182639.1_CAT1 cds-NP_013857.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:515395-517380:- gene-YMR137C_CBS1585 rna-NM_001182639.1_CBS1585 cds-NP_013857.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:519288-521273:- gene-YMR137C_CBS436 rna-NM_001182639.1_CBS436 cds-NP_013857.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:628388-630373:- gene-YMR137C_CBS6412 rna-NM_001182639.1_CBS6412 cds-NP_013857.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:513955-515940:- gene-YMR137C_CBS6413 rna-NM_001182639.1_CBS6413 cds-NP_013857.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:537491-539476:- gene-YMR137C_CENPK1137D rna-NM_001182639.1_CENPK1137D cds-NP_013857.1_CENPK1137D 99.5 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:513584-515569:- gene-YMR137C_EthanolRed rna-NM_001182639.1_EthanolRed cds-NP_013857.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:520582-522567:- gene-YMR137C_FaliES1 rna-NM_001182639.1_FaliES1 cds-NP_013857.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000294.1:5474-7459:+ gene-YMR137C_JAY291 rna-NM_001182639.1_JAY291 cds-NP_013857.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:520383-522368:- gene-YMR137C_MUCL30387 rna-NM_001182639.1_MUCL30387 cds-NP_013857.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:525911-527896:- gene-YMR137C_MUCL30388 rna-NM_001182639.1_MUCL30388 cds-NP_013857.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:516096-518081:- gene-YMR137C_MUCL39482 rna-NM_001182639.1_MUCL39482 cds-NP_013857.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:522394-524379:- gene-YMR137C_MUCL42920 rna-NM_001182639.1_MUCL42920 cds-NP_013857.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:542932-544917:- gene-YMR137C_NCIM3186 rna-NM_001182639.1_NCIM3186 cds-NP_013857.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:515734-517719:- gene-YMR137C_NCYC1407 rna-NM_001182639.1_NCYC1407 cds-NP_013857.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:526175-528160:- gene-YMR137C_PE2H3 rna-NM_001182639.1_PE2H3 cds-NP_013857.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:526630-528615:- gene-YMR137C_PE2H4 rna-NM_001182639.1_PE2H4 cds-NP_013857.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:542978-544963:- gene-YMR137C_S288C rna-NM_001182639.1_S288C cds-NP_013857.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000048.1:26306-28291:+ gene-YMR137C_SA1 rna-NM_001182639.1_SA1 cds-NP_013857.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:515981-517966:- gene-YMR137C_ThermosaccDry rna-NM_001182639.1_ThermosaccDry cds-NP_013857.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:528684-530669:- gene-YMR137C_VR1 rna-NM_001182639.1_VR1 cds-NP_013857.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:491125-493110:- gene-YMR137C_ZTW1 rna-NM_001182639.1_ZTW1 cds-NP_013857.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:527410-529404:- gene-YMR137C_Sparadoxus rna-NM_001182639.1_Sparadoxus cds-NP_013857.1_Sparadoxus 87.5 99.7 Verified 1 1 1 False True False False False

Additional files