PSH1 (YOL054W)


Gene profile

Gene name: PSH1
Reference locus (S288C): YOL054W
Gene biotype: protein_coding

Description: RING finger protein PSH1; E3 ubiquitin ligase targeting centromere-binding protein Cse4p; mediates polyubiquitination and degradation of histone H3 variant Cse4p, preventing its mislocalization to euchromatin independent of Slx5p; ubiquitination of Cse4p may be antagonized by Scm3p

Top 10 interactors (score): CSE4 (0.995); SPT16 (0.959); HHT2 (0.938); SCM3 (0.934); HHF1 (0.93); HHT1 (0.927); POB3 (0.92); DSN1 (0.915); CKA2 (0.855); HTA2 (0.84); FPR3 (0.831); SLX5 (0.827); HTB1 (0.812); TOM1 (0.776); UBC1 (0.768); HTA1 (0.754); HSM3 (0.747); UBC8 (0.739); UBR2 (0.716); HTB2 (0.71)

Homologues (species, bitscore): TRIM25 (Homo sapiens, 55.1); Trim25 (Mus musculus, 52.4); ftr97 (Danio rerio, 63.9); LOC100496318 (Xenopus tropicalis, 59.7); CG13605 (Drosophila melanogaster, 53.1); nhl-1 (Caenorhabditis elegans, 51.2); VIM1 (Arabidopsis thaliana, 53.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:212911-214131:+ gene-YOL054W_AKU4011 rna-NM_001183309.1_AKU4011 cds-NP_014587.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:28572-29792:+ gene-YOL054W_BG1 rna-NM_001183309.1_BG1 cds-NP_014587.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:215802-217022:+ gene-YOL054W_Bruggeman rna-NM_001183309.1_Bruggeman cds-NP_014587.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:213741-214961:+ gene-YOL054W_CAT1 rna-NM_001183309.1_CAT1 cds-NP_014587.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:207578-208798:+ gene-YOL054W_CBS1585 rna-NM_001183309.1_CBS1585 cds-NP_014587.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:211894-213114:+ gene-YOL054W_CBS436 rna-NM_001183309.1_CBS436 cds-NP_014587.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:206975-208195:+ gene-YOL054W_CBS6412 rna-NM_001183309.1_CBS6412 cds-NP_014587.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:214478-215698:+ gene-YOL054W_CBS6413 rna-NM_001183309.1_CBS6413 cds-NP_014587.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:228316-229536:+ gene-YOL054W_CENPK1137D rna-NM_001183309.1_CENPK1137D cds-NP_014587.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:209933-211153:+ gene-YOL054W_EthanolRed rna-NM_001183309.1_EthanolRed cds-NP_014587.1_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:212850-214070:+ gene-YOL054W_FaliES1 rna-NM_001183309.1_FaliES1 cds-NP_014587.1_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000018.1:52387-53607:- gene-YOL054W_JAY291 rna-NM_001183309.1_JAY291 cds-NP_014587.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:218574-219794:+ gene-YOL054W_MUCL30387 rna-NM_001183309.1_MUCL30387 cds-NP_014587.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:223172-224392:+ gene-YOL054W_MUCL30388 rna-NM_001183309.1_MUCL30388 cds-NP_014587.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:215096-216316:+ gene-YOL054W_MUCL39482 rna-NM_001183309.1_MUCL39482 cds-NP_014587.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:230077-231297:+ gene-YOL054W_MUCL42920 rna-NM_001183309.1_MUCL42920 cds-NP_014587.1_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:228503-229723:+ gene-YOL054W_NCIM3186 rna-NM_001183309.1_NCIM3186 cds-NP_014587.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:221840-223060:+ gene-YOL054W_NCYC1407 rna-NM_001183309.1_NCYC1407 cds-NP_014587.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:204261-205481:+ gene-YOL054W_PE2H3 rna-NM_001183309.1_PE2H3 cds-NP_014587.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:215235-216455:+ gene-YOL054W_PE2H4 rna-NM_001183309.1_PE2H4 cds-NP_014587.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:228614-229834:+ gene-YOL054W_S288C rna-NM_001183309.1_S288C cds-NP_014587.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:196585-197805:+ gene-YOL054W_SA1 rna-NM_001183309.1_SA1 cds-NP_014587.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:211419-212639:+ gene-YOL054W_ThermosaccDry rna-NM_001183309.1_ThermosaccDry cds-NP_014587.1_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:211489-212709:+ gene-YOL054W_VR1 rna-NM_001183309.1_VR1 cds-NP_014587.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000031.1:211297-212517:+ gene-YOL054W_ZTW1 rna-NM_001183309.1_ZTW1 cds-NP_014587.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:219641-220864:+ gene-YOL054W_Sparadoxus rna-NM_001183309.1_Sparadoxus cds-NP_014587.1_Sparadoxus 88.7 99.5 Verified 1 1 1 False True False False False

Additional files