Gene name: PRS5
Reference locus (S288C): YOL061W
Gene biotype: protein_coding
Description: Ribose-phosphate pyrophosphokinase 5; 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; forms cytoplasmic foci upon DNA replication stress; Belongs to the ribose-phosphate pyrophosphokinase family
Top 10 interactors (score): PRS4 (0.984); PRS1 (0.982); PRS2 (0.979); PRS3 (0.967); RBK1 (0.95); RKI1 (0.947); ADE4 (0.933); YSA1 (0.903); HIS1 (0.835); PRM15 (0.758); TKL1 (0.75); TKL2 (0.719); PGM2 (0.7); PDB1 (0.698); IDH2 (0.685); IMP4 (0.68); URA5 (0.673); CTP1 (0.669); PGM1 (0.665); DBP8 (0.658)
Homologues (species, bitscore): PRPS2 (Homo sapiens, 279.6); Prps2 (Mus musculus, 275.4); prps1a (Danio rerio, 275.8); prps1 (Xenopus tropicalis, 271.9); CG6767 (Drosophila melanogaster, 283.1); R151.2 (Caenorhabditis elegans, 281.6); AT2G35390 (Arabidopsis thaliana, 173.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:195896-197386:+ | gene-YOL061W_AKU4011 | rna-NM_001183316.1_AKU4011 | cds-NP_014580.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:11766-13256:+ | gene-YOL061W_BG1 | rna-NM_001183316.1_BG1 | cds-NP_014580.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:197565-199055:+ | gene-YOL061W_Bruggeman | rna-NM_001183316.1_Bruggeman | cds-NP_014580.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:197081-198571:+ | gene-YOL061W_CAT1 | rna-NM_001183316.1_CAT1 | cds-NP_014580.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:190287-191777:+ | gene-YOL061W_CBS1585 | rna-NM_001183316.1_CBS1585 | cds-NP_014580.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:195450-196940:+ | gene-YOL061W_CBS436 | rna-NM_001183316.1_CBS436 | cds-NP_014580.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:190216-191706:+ | gene-YOL061W_CBS6412 | rna-NM_001183316.1_CBS6412 | cds-NP_014580.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:197152-198642:+ | gene-YOL061W_CBS6413 | rna-NM_001183316.1_CBS6413 | cds-NP_014580.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:211992-213482:+ | gene-YOL061W_CENPK1137D | rna-NM_001183316.1_CENPK1137D | cds-NP_014580.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:192996-194486:+ | gene-YOL061W_EthanolRed | rna-NM_001183316.1_EthanolRed | cds-NP_014580.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:195539-197029:+ | gene-YOL061W_FaliES1 | rna-NM_001183316.1_FaliES1 | cds-NP_014580.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000018.1:68528-70018:- | gene-YOL061W_JAY291 | rna-NM_001183316.1_JAY291 | cds-NP_014580.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:201330-202820:+ | gene-YOL061W_MUCL30387 | rna-NM_001183316.1_MUCL30387 | cds-NP_014580.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:205014-206504:+ | gene-YOL061W_MUCL30388 | rna-NM_001183316.1_MUCL30388 | cds-NP_014580.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:198207-199697:+ | gene-YOL061W_MUCL39482 | rna-NM_001183316.1_MUCL39482 | cds-NP_014580.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:213687-215177:+ | gene-YOL061W_MUCL42920 | rna-NM_001183316.1_MUCL42920 | cds-NP_014580.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:212133-213623:+ | gene-YOL061W_NCIM3186 | rna-NM_001183316.1_NCIM3186 | cds-NP_014580.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:204824-206314:+ | gene-YOL061W_NCYC1407 | rna-NM_001183316.1_NCYC1407 | cds-NP_014580.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:187832-189322:+ | gene-YOL061W_PE2H3 | rna-NM_001183316.1_PE2H3 | cds-NP_014580.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:198822-200312:+ | gene-YOL061W_PE2H4 | rna-NM_001183316.1_PE2H4 | cds-NP_014580.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:212244-213734:+ | gene-YOL061W_S288C | rna-NM_001183316.1_S288C | cds-NP_014580.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:180180-181670:+ | gene-YOL061W_SA1 | rna-NM_001183316.1_SA1 | cds-NP_014580.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:194547-196037:+ | gene-YOL061W_ThermosaccDry | rna-NM_001183316.1_ThermosaccDry | cds-NP_014580.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:195312-196802:+ | gene-YOL061W_VR1 | rna-NM_001183316.1_VR1 | cds-NP_014580.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:194190-195680:+ | gene-YOL061W_ZTW1 | rna-NM_001183316.1_ZTW1 | cds-NP_014580.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:197716-199206:+ | gene-YOL061W_Sparadoxus | rna-NM_001183316.1_Sparadoxus | cds-NP_014580.1_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |