Gene name: PRS3
Reference locus (S288C): YHL011C
Gene biotype: protein_coding
Description: Ribose-phosphate pyrophosphokinase 3; 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; Belongs to the ribose-phosphate pyrophosphokinase family
Top 10 interactors (score): PRS1 (0.99); PRS5 (0.967); RKI1 (0.965); RBK1 (0.953); PRS4 (0.936); ADE4 (0.934); PRS2 (0.903); YSA1 (0.903); HIS1 (0.835); TKL1 (0.774); PRM15 (0.758); TKL2 (0.751); PGM2 (0.701); URA5 (0.679); PGM1 (0.665); URA10 (0.643); NMD3 (0.632); PUP2 (0.628); NAT2 (0.616); TRP3 (0.612)
Homologues (species, bitscore): PRPS1 (Homo sapiens, 402.5); Prps2 (Mus musculus, 402.9); prps1b (Danio rerio, 406.0); prps1 (Xenopus tropicalis, 398.7); CG6767 (Drosophila melanogaster, 381.7); R151.2 (Caenorhabditis elegans, 385.6); PRS2 (Arabidopsis thaliana, 239.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:75605-76567:- | gene-YHL011C_AKU4011 | rna-NM_001179091.1_AKU4011 | cds-NP_011852.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000180.1:240-1202:+ | gene-YHL011C_BG1 | rna-NM_001179091.1_BG1 | cds-NP_011852.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:82482-83444:- | gene-YHL011C_Bruggeman | rna-NM_001179091.1_Bruggeman | cds-NP_011852.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:76444-77406:- | gene-YHL011C_CAT1 | rna-NM_001179091.1_CAT1 | cds-NP_011852.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:76207-77169:- | gene-YHL011C_CBS1585 | rna-NM_001179091.1_CBS1585 | cds-NP_011852.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:68693-69655:- | gene-YHL011C_CBS436 | rna-NM_001179091.1_CBS436 | cds-NP_011852.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:75799-76761:- | gene-YHL011C_CBS6412 | rna-NM_001179091.1_CBS6412 | cds-NP_011852.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:75579-76541:- | gene-YHL011C_CBS6413 | rna-NM_001179091.1_CBS6413 | cds-NP_011852.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:73807-74769:- | gene-YHL011C_CENPK1137D | rna-NM_001179091.1_CENPK1137D | cds-NP_011852.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:75608-76570:- | gene-YHL011C_EthanolRed | rna-NM_001179091.1_EthanolRed | cds-NP_011852.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:76139-77101:- | gene-YHL011C_FaliES1 | rna-NM_001179091.1_FaliES1 | cds-NP_011852.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000003.1:44813-45775:- | gene-YHL011C_JAY291 | rna-NM_001179091.1_JAY291 | cds-NP_011852.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:79218-80180:- | gene-YHL011C_MUCL30387 | rna-NM_001179091.1_MUCL30387 | cds-NP_011852.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:80164-81126:- | gene-YHL011C_MUCL30388 | rna-NM_001179091.1_MUCL30388 | cds-NP_011852.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:75217-76179:- | gene-YHL011C_MUCL39482 | rna-NM_001179091.1_MUCL39482 | cds-NP_011852.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:79137-80099:- | gene-YHL011C_MUCL42920 | rna-NM_001179091.1_MUCL42920 | cds-NP_011852.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:80536-81498:- | gene-YHL011C_NCIM3186 | rna-NM_001179091.1_NCIM3186 | cds-NP_011852.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:74644-75606:- | gene-YHL011C_NCYC1407 | rna-NM_001179091.1_NCYC1407 | cds-NP_011852.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:70888-71850:- | gene-YHL011C_PE2H3 | rna-NM_001179091.1_PE2H3 | cds-NP_011852.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:78329-79291:- | gene-YHL011C_PE2H4 | rna-NM_001179091.1_PE2H4 | cds-NP_011852.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:80654-81616:- | gene-YHL011C_S288C | rna-NM_001179091.1_S288C | cds-NP_011852.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:64983-65945:- | gene-YHL011C_SA1 | rna-NM_001179091.1_SA1 | cds-NP_011852.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:77234-78196:- | gene-YHL011C_ThermosaccDry | rna-NM_001179091.1_ThermosaccDry | cds-NP_011852.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:82775-83737:- | gene-YHL011C_VR1 | rna-NM_001179091.1_VR1 | cds-NP_011852.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:68402-69364:- | gene-YHL011C_ZTW1 | rna-NM_001179091.1_ZTW1 | cds-NP_011852.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:74759-75721:- | gene-YHL011C_Sparadoxus | rna-NM_001179091.1_Sparadoxus | cds-NP_011852.1_Sparadoxus | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |