Gene name: PRR2
Reference locus (S288C): YDL214C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase PRR2; Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication
Top 10 interactors (score): MEC1 (0.875); FHN1 (0.851); RHO5 (0.816); DPB11 (0.756); NCE102 (0.75); TOF1 (0.742); TEL1 (0.739); CSM3 (0.711); CDC45 (0.698); RAD24 (0.697); RAD51 (0.679); RHO3 (0.655); RAD17 (0.637); ARR2 (0.612); YCH1 (0.612); MIH1 (0.612); MCM4 (0.606); KNS1 (0.593); RFC4 (0.586); CDC6 (0.584)
Homologues (species, bitscore): CHEK1 (Homo sapiens, 110.9); Chek1 (Mus musculus, 112.5); chek1 (Danio rerio, 112.8); chek1 (Xenopus tropicalis, 108.6); Sik3 (Drosophila melanogaster, 108.6); R02C2.6 (Caenorhabditis elegans, 117.5); CIPK9 (Arabidopsis thaliana, 117.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:57933-60032:- | gene-YDL214C_AKU4011 | rna-NM_001180274.1_AKU4011 | cds-NP_010067.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000077.1:7040-9136:+ | gene-YDL214C_BG1 | rna-NM_001180274.1_BG1 | cds-NP_010067.1_BG1 | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:73610-75625:- | gene-YDL214C_Bruggeman | rna-NM_001180274.1_Bruggeman | cds-NP_010067.1_Bruggeman | 90.7 | 94.9 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:293460-295559:- | gene-YDL214C_CAT1 | rna-NM_001180274.1_CAT1 | cds-NP_010067.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:56808-58907:- | gene-YDL214C_CBS1585 | rna-NM_001180274.1_CBS1585 | cds-NP_010067.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:271691-273787:- | gene-YDL214C_CBS436 | rna-NM_001180274.1_CBS436 | cds-NP_010067.1_CBS436 | 99.2 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:56920-59019:- | gene-YDL214C_CBS6412 | rna-NM_001180274.1_CBS6412 | cds-NP_010067.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:74443-76542:- | gene-YDL214C_CBS6413 | rna-NM_001180274.1_CBS6413 | cds-NP_010067.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:73112-75211:- | gene-YDL214C_CENPK1137D | rna-NM_001180274.1_CENPK1137D | cds-NP_010067.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:70379-72478:- | gene-YDL214C_EthanolRed | rna-NM_001180274.1_EthanolRed | cds-NP_010067.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:74706-76805:- | gene-YDL214C_FaliES1 | rna-NM_001180274.1_FaliES1 | cds-NP_010067.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000213.1:29035-31131:- | gene-YDL214C_JAY291 | rna-NM_001180274.1_JAY291 | cds-NP_010067.1_JAY291 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:72559-74655:- | gene-YDL214C_MUCL30387 | rna-NM_001180274.1_MUCL30387 | cds-NP_010067.1_MUCL30387 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:280377-282473:- | gene-YDL214C_MUCL30388 | rna-NM_001180274.1_MUCL30388 | cds-NP_010067.1_MUCL30388 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:57651-59750:- | gene-YDL214C_MUCL39482 | rna-NM_001180274.1_MUCL39482 | cds-NP_010067.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:73708-75807:- | gene-YDL214C_MUCL42920 | rna-NM_001180274.1_MUCL42920 | cds-NP_010067.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:74369-76468:- | gene-YDL214C_NCIM3186 | rna-NM_001180274.1_NCIM3186 | cds-NP_010067.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:57607-59706:- | gene-YDL214C_NCYC1407 | rna-NM_001180274.1_NCYC1407 | cds-NP_010067.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:64648-66744:- | gene-YDL214C_PE2H3 | rna-NM_001180274.1_PE2H3 | cds-NP_010067.1_PE2H3 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:64658-66754:- | gene-YDL214C_PE2H4 | rna-NM_001180274.1_PE2H4 | cds-NP_010067.1_PE2H4 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:74446-76545:- | gene-YDL214C_S288C | rna-NM_001180274.1_S288C | cds-NP_010067.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000094.1:28843-30939:- | gene-YDL214C_SA1 | rna-NM_001180274.1_SA1 | cds-NP_010067.1_SA1 | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:74461-76560:- | gene-YDL214C_ThermosaccDry | rna-NM_001180274.1_ThermosaccDry | cds-NP_010067.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:75415-77511:- | gene-YDL214C_VR1 | rna-NM_001180274.1_VR1 | cds-NP_010067.1_VR1 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:73631-75730:- | gene-YDL214C_ZTW1 | rna-NM_001180274.1_ZTW1 | cds-NP_010067.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:77021-79105:- | gene-YDL214C_Sparadoxus | rna-NM_001180274.1_Sparadoxus | cds-NP_010067.1_Sparadoxus | 86.3 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |