PRP45 (YAL032C)


Gene profile

Gene name: PRP45
Reference locus (S288C): YAL032C
Gene biotype: protein_coding

Description: Snw domain-containing protein 1; Pre-mRNA-processing protein 45; Protein required for pre-mRNA splicing; associates with the spliceosome and interacts with splicing factors Prp22p and Prp46p; orthologous to human transcriptional coactivator SKIP and can activate transcription of a reporter gene

Top 10 interactors (score): CLF1 (0.999); PRP16 (0.999); CAM1 (0.999); PRP46 (0.999); LEA1 (0.999); BRR2 (0.999); PRP8 (0.999); TEF4 (0.999); ISY1 (0.999); SYF1 (0.999); PRP22 (0.999); SNU114 (0.999); CWC2 (0.999); PRP43 (0.999); PRP19 (0.999); CWC15 (0.999); SYF2 (0.999); BUD31 (0.999); SNT309 (0.999); ECM2 (0.999)

Homologues (species, bitscore): SNW1 (Homo sapiens, 103.2); Snw1 (Mus musculus, 103.2); snw1 (Danio rerio, 89.4); snw1 (Xenopus tropicalis, 103.6); Bx42 (Drosophila melanogaster, 97.4); skp-1 (Caenorhabditis elegans, 109.4); SKIP (Arabidopsis thaliana, 91.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005295.1:68460-69599:- gene-YAL032C_AKU4011 rna-NM_001178177.1_AKU4011 cds-NP_009370.1_AKU4011 99.1 100.0 Verified 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000070.1:55589-56728:- gene-YAL032C_BG1 rna-NM_001178177.1_BG1 cds-NP_009370.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005503.1:83341-84480:- gene-YAL032C_Bruggeman rna-NM_001178177.1_Bruggeman cds-NP_009370.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005519.1:69687-70826:- gene-YAL032C_CAT1 rna-NM_001178177.1_CAT1 cds-NP_009370.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005359.1:81477-82616:- gene-YAL032C_CBS1585 rna-NM_001178177.1_CBS1585 cds-NP_009370.1_CBS1585 99.1 100.0 Verified 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005343.1:81728-82867:- gene-YAL032C_CBS436 rna-NM_001178177.1_CBS436 cds-NP_009370.1_CBS436 99.9 100.0 Mismatch 1 1 0 False False False True False
CBS6412 GCA_001738345.1 Sake Asia CM005327.1:67623-68762:- gene-YAL032C_CBS6412 rna-NM_001178177.1_CBS6412 cds-NP_009370.1_CBS6412 99.1 100.0 Mismatch 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005311.1:79742-80881:- gene-YAL032C_CBS6413 rna-NM_001178177.1_CBS6413 cds-NP_009370.1_CBS6413 99.0 100.0 Verified 1 1 0 False False False True False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001522.1:83425-84564:- gene-YAL032C_CENPK1137D rna-NM_001178177.1_CENPK1137D cds-NP_009370.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005471.1:69881-71020:- gene-YAL032C_EthanolRed rna-NM_001178177.1_EthanolRed cds-NP_009370.1_EthanolRed 99.2 100.0 Verified 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005535.1:84504-85643:- gene-YAL032C_FaliES1 rna-NM_001178177.1_FaliES1 cds-NP_009370.1_FaliES1 99.2 100.0 Verified 1 1 0 False False False True False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000084.1:55779-56918:- gene-YAL032C_JAY291 rna-NM_001178177.1_JAY291 cds-NP_009370.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005407.1:84430-85569:- gene-YAL032C_MUCL30387 rna-NM_001178177.1_MUCL30387 cds-NP_009370.1_MUCL30387 99.6 100.0 Verified 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005439.1:80980-82119:- gene-YAL032C_MUCL30388 rna-NM_001178177.1_MUCL30388 cds-NP_009370.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005279.1:80263-81402:- gene-YAL032C_MUCL39482 rna-NM_001178177.1_MUCL39482 cds-NP_009370.1_MUCL39482 99.1 100.0 Verified 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe CM005423.1:82636-83775:- gene-YAL032C_MUCL42920 rna-NM_001178177.1_MUCL42920 cds-NP_009370.1_MUCL42920 99.6 100.0 Verified 1 1 0 False False False True False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011810.1:83212-84351:- gene-YAL032C_NCIM3186 rna-NM_001178177.1_NCIM3186 cds-NP_009370.1_NCIM3186 99.2 100.0 Verified 1 1 0 False False False True False
NCYC1407 GCA_001738225.1 Sake Asia CM005263.1:68142-69281:- gene-YAL032C_NCYC1407 rna-NM_001178177.1_NCYC1407 cds-NP_009370.1_NCYC1407 99.0 100.0 Verified 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994140.1:70049-71188:- gene-YAL032C_PE2H3 rna-NM_001178177.1_PE2H3 cds-NP_009370.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999872.1:69768-70907:- gene-YAL032C_PE2H4 rna-NM_001178177.1_PE2H4 cds-NP_009370.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001133.9:83335-84474:- gene-YAL032C_S288C rna-NM_001178177.1_S288C cds-NP_009370.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000059.1:12459-13598:- gene-YAL032C_SA1 rna-NM_001178177.1_SA1 cds-NP_009370.1_SA1 99.8 100.0 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005487.1:84022-85161:- gene-YAL032C_ThermosaccDry rna-NM_001178177.1_ThermosaccDry cds-NP_009370.1_ThermosaccDry 99.2 100.0 Verified 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America CM005455.1:85303-86442:- gene-YAL032C_VR1 rna-NM_001178177.1_VR1 cds-NP_009370.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000002.1:55842-56981:- gene-YAL032C_ZTW1 rna-NM_001178177.1_ZTW1 cds-NP_009370.1_ZTW1 99.0 100.0 Verified 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047487.1:73406-74542:- gene-YAL032C_Sparadoxus rna-NM_001178177.1_Sparadoxus cds-NP_009370.1_Sparadoxus 89.6 99.7 Verified 1 1 0 False False False True False

Additional files