Gene name: PRP43
Reference locus (S288C): YGL120C
Gene biotype: protein_coding
Description: Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43; RNA helicase in the DEAH-box family; functions in both RNA polymerase I and polymerase II transcript metabolism; catalyzes removal of U2, U5, and U6 snRNPs from the postsplicing lariat-intron ribonucleoprotein complex; required for efficient biogenesis of both small- and large-subunit rRNAs; acts with Sqs1p to promote 20S to 18S rRNA processing catalyzed by endonuclease Nob1p; Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily
Top 10 interactors (score): CBF5 (0.999); PRP45 (0.999); SYF1 (0.999); RRP5 (0.999); BMS1 (0.999); DBP3 (0.999); UTP4 (0.999); DBP2 (0.999); KRE33 (0.999); NOP9 (0.999); UTP21 (0.999); UTP10 (0.999); CLF1 (0.999); SAS10 (0.999); ENP2 (0.999); NOP7 (0.999); PRP8 (0.999); PWP2 (0.999); SQS1 (0.999); ERB1 (0.999)
Homologues (species, bitscore): DHX15 (Homo sapiens, 908.3); Dhx15 (Mus musculus, 907.1); dhx15 (Danio rerio, 899.8); dhx15 (Xenopus tropicalis, 901.0); CG11107 (Drosophila melanogaster, 894.8); F56D2.6 (Caenorhabditis elegans, 877.9); AT3G62310 (Arabidopsis thaliana, 897.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:284383-286686:- | gene-YGL120C_AKU4011 | rna-NM_001180985.1_AKU4011 | cds-NP_011395.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:118479-120782:+ | gene-YGL120C_BG1 | rna-NM_001180985.1_BG1 | cds-NP_011395.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:287125-289428:- | gene-YGL120C_Bruggeman | rna-NM_001180985.1_Bruggeman | cds-NP_011395.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:282645-284948:- | gene-YGL120C_CAT1 | rna-NM_001180985.1_CAT1 | cds-NP_011395.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:287709-290012:- | gene-YGL120C_CBS1585 | rna-NM_001180985.1_CBS1585 | cds-NP_011395.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:282598-284901:- | gene-YGL120C_CBS436 | rna-NM_001180985.1_CBS436 | cds-NP_011395.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:272986-275289:- | gene-YGL120C_CBS6412 | rna-NM_001180985.1_CBS6412 | cds-NP_011395.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:282586-284889:- | gene-YGL120C_CBS6413 | rna-NM_001180985.1_CBS6413 | cds-NP_011395.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:281821-284124:- | gene-YGL120C_CENPK1137D | rna-NM_001180985.1_CENPK1137D | cds-NP_011395.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:273905-276208:- | gene-YGL120C_EthanolRed | rna-NM_001180985.1_EthanolRed | cds-NP_011395.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:276086-278389:- | gene-YGL120C_FaliES1 | rna-NM_001180985.1_FaliES1 | cds-NP_011395.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000046.1:23250-25553:+ | gene-YGL120C_JAY291 | rna-NM_001180985.1_JAY291 | cds-NP_011395.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:284095-286398:- | gene-YGL120C_MUCL30387 | rna-NM_001180985.1_MUCL30387 | cds-NP_011395.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:287187-289490:- | gene-YGL120C_MUCL30388 | rna-NM_001180985.1_MUCL30388 | cds-NP_011395.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:284806-287109:- | gene-YGL120C_MUCL39482 | rna-NM_001180985.1_MUCL39482 | cds-NP_011395.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:288087-290390:- | gene-YGL120C_MUCL42920 | rna-NM_001180985.1_MUCL42920 | cds-NP_011395.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:281634-283937:- | gene-YGL120C_NCIM3186 | rna-NM_001180985.1_NCIM3186 | cds-NP_011395.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:276296-278599:- | gene-YGL120C_NCYC1407 | rna-NM_001180985.1_NCYC1407 | cds-NP_011395.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:277677-279980:- | gene-YGL120C_PE2H3 | rna-NM_001180985.1_PE2H3 | cds-NP_011395.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:282675-284978:- | gene-YGL120C_PE2H4 | rna-NM_001180985.1_PE2H4 | cds-NP_011395.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:281634-283937:- | gene-YGL120C_S288C | rna-NM_001180985.1_S288C | cds-NP_011395.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000064.1:26430-28733:- | gene-YGL120C_SA1 | rna-NM_001180985.1_SA1 | cds-NP_011395.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:276298-278601:- | gene-YGL120C_ThermosaccDry | rna-NM_001180985.1_ThermosaccDry | cds-NP_011395.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:386404-388707:- | gene-YGL120C_VR1 | rna-NM_001180985.1_VR1 | cds-NP_011395.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:273866-276169:- | gene-YGL120C_ZTW1 | rna-NM_001180985.1_ZTW1 | cds-NP_011395.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:279881-282184:- | gene-YGL120C_Sparadoxus | rna-NM_001180985.1_Sparadoxus | cds-NP_011395.1_Sparadoxus | 93.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |