Gene name: PRP22
Reference locus (S288C): YER013W
Gene biotype: protein_coding
Description: DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase; associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes; required for proofreading the exon ligation reaction
Top 10 interactors (score): PRP46 (0.999); SLU7 (0.999); CWC22 (0.999); MSL1 (0.999); CWC21 (0.999); SYF1 (0.999); BUD31 (0.999); PRP45 (0.999); PRP18 (0.999); ECM2 (0.999); BRR2 (0.999); PRP8 (0.999); SYF2 (0.999); CWC15 (0.999); PRP19 (0.999); LEA1 (0.999); CWC2 (0.999); SNU114 (0.999); CEF1 (0.999); CDC40 (0.999)
Homologues (species, bitscore): DHX8 (Homo sapiens, 965.7); Dhx8 (Mus musculus, 967.2); dhx8 (Danio rerio, 972.2); dhx8 (Xenopus tropicalis, 943.3); pea (Drosophila melanogaster, 970.3); mog-5 (Caenorhabditis elegans, 980.7); AT3G26560 (Arabidopsis thaliana, 959.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:172886-176323:+ | gene-YER013W_AKU4011 | rna-NM_001178904.3_AKU4011 | cds-NP_010929.3_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:249776-253213:- | gene-YER013W_BG1 | rna-NM_001178904.3_BG1 | cds-NP_010929.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:180745-184182:+ | gene-YER013W_Bruggeman | rna-NM_001178904.3_Bruggeman | cds-NP_010929.3_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:175387-178824:+ | gene-YER013W_CAT1 | rna-NM_001178904.3_CAT1 | cds-NP_010929.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:172809-176246:+ | gene-YER013W_CBS1585 | rna-NM_001178904.3_CBS1585 | cds-NP_010929.3_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:174376-177820:+ | gene-YER013W_CBS436 | rna-NM_001178904.3_CBS436 | cds-NP_010929.3_CBS436 | 97.8 | 99.5 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:173053-176490:+ | gene-YER013W_CBS6412 | rna-NM_001178904.3_CBS6412 | cds-NP_010929.3_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:177839-181276:+ | gene-YER013W_CBS6413 | rna-NM_001178904.3_CBS6413 | cds-NP_010929.3_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:176703-180140:+ | gene-YER013W_CENPK1137D | rna-NM_001178904.3_CENPK1137D | cds-NP_010929.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:173512-176949:+ | gene-YER013W_EthanolRed | rna-NM_001178904.3_EthanolRed | cds-NP_010929.3_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:173772-177209:+ | gene-YER013W_FaliES1 | rna-NM_001178904.3_FaliES1 | cds-NP_010929.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000024.1:40398-43835:+ | gene-YER013W_JAY291 | rna-NM_001178904.3_JAY291 | cds-NP_010929.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:176938-180375:+ | gene-YER013W_MUCL30387 | rna-NM_001178904.3_MUCL30387 | cds-NP_010929.3_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:173213-176650:+ | gene-YER013W_MUCL30388 | rna-NM_001178904.3_MUCL30388 | cds-NP_010929.3_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:171852-175289:+ | gene-YER013W_MUCL39482 | rna-NM_001178904.3_MUCL39482 | cds-NP_010929.3_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:177969-181406:+ | gene-YER013W_MUCL42920 | rna-NM_001178904.3_MUCL42920 | cds-NP_010929.3_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:178840-182277:+ | gene-YER013W_NCIM3186 | rna-NM_001178904.3_NCIM3186 | cds-NP_010929.3_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:176924-180361:+ | gene-YER013W_NCYC1407 | rna-NM_001178904.3_NCYC1407 | cds-NP_010929.3_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:181225-184662:+ | gene-YER013W_PE2H3 | rna-NM_001178904.3_PE2H3 | cds-NP_010929.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:177140-180577:+ | gene-YER013W_PE2H4 | rna-NM_001178904.3_PE2H4 | cds-NP_010929.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:178841-182278:+ | gene-YER013W_S288C | rna-NM_001178904.3_S288C | cds-NP_010929.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000020.1:61392-64829:- | gene-YER013W_SA1 | rna-NM_001178904.3_SA1 | cds-NP_010929.3_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:174543-177980:+ | gene-YER013W_ThermosaccDry | rna-NM_001178904.3_ThermosaccDry | cds-NP_010929.3_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:173284-176721:+ | gene-YER013W_VR1 | rna-NM_001178904.3_VR1 | cds-NP_010929.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:171755-175192:+ | gene-YER013W_ZTW1 | rna-NM_001178904.3_ZTW1 | cds-NP_010929.3_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:176355-179792:+ | gene-YER013W_Sparadoxus | rna-NM_001178904.3_Sparadoxus | cds-NP_010929.3_Sparadoxus | 90.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |