PRP2 (YNR011C)


Gene profile

Gene name: PRP2
Reference locus (S288C): YNR011C
Gene biotype: protein_coding

Description: Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2; RNA-dependent DExD/H-box ATPase; required for activation of spliceosome before first transesterification step in RNA splicing; implicated in rearranging and proofreading snRNA structure in catalytic activation of spliceosome; ortholog of human protein DHX16

Top 10 interactors (score): PRP8 (0.999); CUS1 (0.999); BRR2 (0.999); SNU114 (0.999); CEF1 (0.999); CDC40 (0.999); SYF1 (0.999); PRP19 (0.998); HSH155 (0.995); CWC22 (0.995); PRP11 (0.994); IST3 (0.994); CLF1 (0.994); RSE1 (0.994); BUD13 (0.993); CWC24 (0.989); CWC27 (0.988); PRP45 (0.987); ECM2 (0.986); PML1 (0.986)

Homologues (species, bitscore): DHX16 (Homo sapiens, 644.8); Dhx16 (Mus musculus, 649.4); dhx16 (Danio rerio, 648.7); dhx8 (Xenopus tropicalis, 597.8); l(2)37Cb (Drosophila melanogaster, 652.9); mog-4 (Caenorhabditis elegans, 676.0); MEE29 (Arabidopsis thaliana, 639.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:627904-630534:- gene-YNR011C_AKU4011 rna-NM_001183188.1_AKU4011 cds-NP_014408.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:535758-538388:- gene-YNR011C_BG1 rna-NM_001183188.1_BG1 cds-NP_014408.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:645395-648025:- gene-YNR011C_Bruggeman rna-NM_001183188.1_Bruggeman cds-NP_014408.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:679621-682251:- gene-YNR011C_CAT1 rna-NM_001183188.1_CAT1 cds-NP_014408.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:633700-636330:- gene-YNR011C_CBS1585 rna-NM_001183188.1_CBS1585 cds-NP_014408.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:695392-698022:- gene-YNR011C_CBS436 rna-NM_001183188.1_CBS436 cds-NP_014408.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:623266-625896:- gene-YNR011C_CBS6412 rna-NM_001183188.1_CBS6412 cds-NP_014408.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:624594-627224:- gene-YNR011C_CBS6413 rna-NM_001183188.1_CBS6413 cds-NP_014408.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:638006-640636:- gene-YNR011C_CENPK1137D rna-NM_001183188.1_CENPK1137D cds-NP_014408.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:629820-632450:- gene-YNR011C_EthanolRed rna-NM_001183188.1_EthanolRed cds-NP_014408.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:620838-623468:- gene-YNR011C_FaliES1 rna-NM_001183188.1_FaliES1 cds-NP_014408.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000037.1:79271-81901:+ gene-YNR011C_JAY291 rna-NM_001183188.1_JAY291 cds-NP_014408.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:643149-645779:- gene-YNR011C_MUCL30387 rna-NM_001183188.1_MUCL30387 cds-NP_014408.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:683981-686611:- gene-YNR011C_MUCL30388 rna-NM_001183188.1_MUCL30388 cds-NP_014408.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:625206-627836:- gene-YNR011C_MUCL39482 rna-NM_001183188.1_MUCL39482 cds-NP_014408.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:629390-632020:- gene-YNR011C_MUCL42920 rna-NM_001183188.1_MUCL42920 cds-NP_014408.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:644289-646919:- gene-YNR011C_NCIM3186 rna-NM_001183188.1_NCIM3186 cds-NP_014408.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:627712-630342:- gene-YNR011C_NCYC1407 rna-NM_001183188.1_NCYC1407 cds-NP_014408.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:628799-631429:- gene-YNR011C_PE2H3 rna-NM_001183188.1_PE2H3 cds-NP_014408.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:630117-632747:- gene-YNR011C_PE2H4 rna-NM_001183188.1_PE2H4 cds-NP_014408.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:644320-646950:- gene-YNR011C_S288C rna-NM_001183188.1_S288C cds-NP_014408.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000068.1:42024-44654:- gene-YNR011C_SA1 rna-NM_001183188.1_SA1 cds-NP_014408.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:621178-623808:- gene-YNR011C_ThermosaccDry rna-NM_001183188.1_ThermosaccDry cds-NP_014408.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:663144-665774:- gene-YNR011C_VR1 rna-NM_001183188.1_VR1 cds-NP_014408.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:530086-532716:- gene-YNR011C_ZTW1 rna-NM_001183188.1_ZTW1 cds-NP_014408.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:635283-637913:- gene-YNR011C_Sparadoxus rna-NM_001183188.1_Sparadoxus cds-NP_014408.1_Sparadoxus 89.5 99.9 Verified 1 1 1 False True False False False

Additional files