PRP19 (YLL036C)


Gene profile

Gene name: PRP19
Reference locus (S288C): YLL036C
Gene biotype: protein_coding

Description: Pre-mRNA-processing factor 19; Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiquitin ligases, and a WD40 domain; relocalizes to the cytosol in response to hypoxia; Belongs to the WD repeat PRP19 family

Top 10 interactors (score): CWC25 (0.999); CWC23 (0.999); SMX3 (0.999); SPP2 (0.999); SNU66 (0.999); SMD2 (0.999); PRP9 (0.999); CDC40 (0.999); BRR2 (0.999); PRP8 (0.999); CUS1 (0.999); SNU114 (0.999); CWC2 (0.999); SMX2 (0.999); RSE1 (0.999); PRP43 (0.999); SYF2 (0.999); CWC15 (0.999); CWC24 (0.999); LEA1 (0.999)

Homologues (species, bitscore): PRPF19 (Homo sapiens, 102.4); Prpf19 (Mus musculus, 90.9); prp19 (Danio rerio, 105.9); prpf19 (Xenopus tropicalis, 100.9); Prp19 (Drosophila melanogaster, 96.7); prp-19 (Caenorhabditis elegans, 93.6); MAC3B (Arabidopsis thaliana, 114.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:53903-55414:- gene-YLL036C_AKU4011 rna-NM_001181856.1_AKU4011 cds-NP_013064.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:17844-19355:- gene-YLL036C_BG1 rna-NM_001181856.1_BG1 cds-NP_013064.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:64153-65664:- gene-YLL036C_Bruggeman rna-NM_001181856.1_Bruggeman cds-NP_013064.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:64781-66292:- gene-YLL036C_CAT1 rna-NM_001181856.1_CAT1 cds-NP_013064.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:61603-63114:- gene-YLL036C_CBS1585 rna-NM_001181856.1_CBS1585 cds-NP_013064.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:51802-53313:- gene-YLL036C_CBS436 rna-NM_001181856.1_CBS436 cds-NP_013064.1_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:61473-62984:- gene-YLL036C_CBS6412 rna-NM_001181856.1_CBS6412 cds-NP_013064.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:61599-63110:- gene-YLL036C_CBS6413 rna-NM_001181856.1_CBS6413 cds-NP_013064.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:51752-53263:- gene-YLL036C_CENPK1137D rna-NM_001181856.1_CENPK1137D cds-NP_013064.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:54300-55811:- gene-YLL036C_EthanolRed rna-NM_001181856.1_EthanolRed cds-NP_013064.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:53613-55124:- gene-YLL036C_FaliES1 rna-NM_001181856.1_FaliES1 cds-NP_013064.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000118.1:23879-25390:+ gene-YLL036C_JAY291 rna-NM_001181856.1_JAY291 cds-NP_013064.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:61564-63075:- gene-YLL036C_MUCL30387 rna-NM_001181856.1_MUCL30387 cds-NP_013064.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:66289-67800:- gene-YLL036C_MUCL30388 rna-NM_001181856.1_MUCL30388 cds-NP_013064.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:61812-63323:- gene-YLL036C_MUCL39482 rna-NM_001181856.1_MUCL39482 cds-NP_013064.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:61661-63172:- gene-YLL036C_MUCL42920 rna-NM_001181856.1_MUCL42920 cds-NP_013064.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:66719-68230:- gene-YLL036C_NCIM3186 rna-NM_001181856.1_NCIM3186 cds-NP_013064.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:53678-55189:- gene-YLL036C_NCYC1407 rna-NM_001181856.1_NCYC1407 cds-NP_013064.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:60364-61875:- gene-YLL036C_PE2H3 rna-NM_001181856.1_PE2H3 cds-NP_013064.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:60173-61684:- gene-YLL036C_PE2H4 rna-NM_001181856.1_PE2H4 cds-NP_013064.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:66745-68256:- gene-YLL036C_S288C rna-NM_001181856.1_S288C cds-NP_013064.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000047.1:60266-61777:- gene-YLL036C_SA1 rna-NM_001181856.1_SA1 cds-NP_013064.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:54119-55630:- gene-YLL036C_ThermosaccDry rna-NM_001181856.1_ThermosaccDry cds-NP_013064.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:67940-69451:- gene-YLL036C_VR1 rna-NM_001181856.1_VR1 cds-NP_013064.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:53669-55180:- gene-YLL036C_ZTW1 rna-NM_001181856.1_ZTW1 cds-NP_013064.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:62294-63805:- gene-YLL036C_Sparadoxus rna-NM_001181856.1_Sparadoxus cds-NP_013064.1_Sparadoxus 85.9 99.8 Verified 1 1 1 False True False False False

Additional files