Gene name: PRP16
Reference locus (S288C): YKR086W
Gene biotype: protein_coding
Description: DEAH-box RNA helicase involved in second catalytic step of splicing and in exon ligation; exhibits ATP-dependent RNA unwinding activity; mediates the release of Yju2p and Cwc25p in the second step; in the absence of ATP, stabilizes the binding of Cwc25p to the spliceosome in the first catalytic step; missense mutation in human ortholog DHX38 associated with early-onset retinitis pigmentosa; Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily
Top 10 interactors (score): PRP19 (0.999); SYF2 (0.999); SNU114 (0.999); BRR2 (0.999); PRP8 (0.999); CDC40 (0.999); CWC25 (0.999); CEF1 (0.999); PRP28 (0.999); YJU2 (0.999); CLF1 (0.999); PRP45 (0.999); ECM2 (0.999); SYF1 (0.999); ISY1 (0.999); PRP18 (0.998); SLU7 (0.998); CWC2 (0.998); LEA1 (0.997); CWC22 (0.997)
Homologues (species, bitscore): DHX38 (Homo sapiens, 773.5); Dhx38 (Mus musculus, 775.4); dhx38 (Danio rerio, 786.9); dhx38 (Xenopus tropicalis, 792.3); l(1)G0007 (Drosophila melanogaster, 803.1); mog-1 (Caenorhabditis elegans, 791.2); EMB3011 (Arabidopsis thaliana, 790.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:585888-589103:+ | gene-YKR086W_AKU4011 | rna-NM_001179876.3_AKU4011 | cds-NP_013012.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:55122-58337:- | gene-YKR086W_BG1 | rna-NM_001179876.3_BG1 | cds-NP_013012.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:608466-611681:+ | gene-YKR086W_Bruggeman | rna-NM_001179876.3_Bruggeman | cds-NP_013012.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:604387-607602:+ | gene-YKR086W_CAT1 | rna-NM_001179876.3_CAT1 | cds-NP_013012.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:598375-601590:+ | gene-YKR086W_CBS1585 | rna-NM_001179876.3_CBS1585 | cds-NP_013012.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:596760-599975:+ | gene-YKR086W_CBS436 | rna-NM_001179876.3_CBS436 | cds-NP_013012.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:581663-584878:+ | gene-YKR086W_CBS6412 | rna-NM_001179876.3_CBS6412 | cds-NP_013012.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:598193-601408:+ | gene-YKR086W_CBS6413 | rna-NM_001179876.3_CBS6413 | cds-NP_013012.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:599512-602727:+ | gene-YKR086W_CENPK1137D | rna-NM_001179876.3_CENPK1137D | cds-NP_013012.3_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:595699-598914:+ | gene-YKR086W_EthanolRed | rna-NM_001179876.3_EthanolRed | cds-NP_013012.3_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:599594-602809:+ | gene-YKR086W_FaliES1 | rna-NM_001179876.3_FaliES1 | cds-NP_013012.3_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000426.1:42124-45339:- | gene-YKR086W_JAY291 | rna-NM_001179876.3_JAY291 | cds-NP_013012.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:607961-611176:+ | gene-YKR086W_MUCL30387 | rna-NM_001179876.3_MUCL30387 | cds-NP_013012.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:602305-605520:+ | gene-YKR086W_MUCL30388 | rna-NM_001179876.3_MUCL30388 | cds-NP_013012.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:597216-600431:+ | gene-YKR086W_MUCL39482 | rna-NM_001179876.3_MUCL39482 | cds-NP_013012.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:603239-606454:+ | gene-YKR086W_MUCL42920 | rna-NM_001179876.3_MUCL42920 | cds-NP_013012.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:599846-603061:+ | gene-YKR086W_NCIM3186 | rna-NM_001179876.3_NCIM3186 | cds-NP_013012.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:597628-600843:+ | gene-YKR086W_NCYC1407 | rna-NM_001179876.3_NCYC1407 | cds-NP_013012.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:622833-626048:+ | gene-YKR086W_PE2H3 | rna-NM_001179876.3_PE2H3 | cds-NP_013012.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:607237-610452:+ | gene-YKR086W_PE2H4 | rna-NM_001179876.3_PE2H4 | cds-NP_013012.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:599857-603072:+ | gene-YKR086W_S288C | rna-NM_001179876.3_S288C | cds-NP_013012.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000029.1:78777-81992:- | gene-YKR086W_SA1 | rna-NM_001179876.3_SA1 | cds-NP_013012.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:598841-602056:+ | gene-YKR086W_ThermosaccDry | rna-NM_001179876.3_ThermosaccDry | cds-NP_013012.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:598104-601319:+ | gene-YKR086W_VR1 | rna-NM_001179876.3_VR1 | cds-NP_013012.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:595822-599037:+ | gene-YKR086W_ZTW1 | rna-NM_001179876.3_ZTW1 | cds-NP_013012.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:621072-624290:+ | gene-YKR086W_Sparadoxus | rna-NM_001179876.3_Sparadoxus | cds-NP_013012.3_Sparadoxus | 87.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |