Gene name: PRO3
Reference locus (S288C): YER023W
Gene biotype: protein_coding
Description: Delta 1-pyrroline-5-carboxylate reductase; catalyzes the last step in proline biosynthesis
Top 10 interactors (score): PRO2 (0.997); THR4 (0.995); TYR1 (0.995); PUT2 (0.991); PUT1 (0.991); PRO1 (0.987); CAR2 (0.981); SER2 (0.98); SSU72 (0.971); ESS1 (0.957); ARG5,6 (0.936); CAR1 (0.928); FCP1 (0.918); PCF11 (0.917); RPO21 (0.915); RTT103 (0.863); YHR033W (0.848); LAT1 (0.848); RTR1 (0.843); KIN28 (0.82)
Homologues (species, bitscore): PYCRL (Homo sapiens, 117.5); Pycr1 (Mus musculus, 121.7); pycr1b (Danio rerio, 116.7); pycr1 (Xenopus tropicalis, 111.3); P5cr (Drosophila melanogaster, 121.7); M153.1 (Caenorhabditis elegans, 116.3); P5CR (Arabidopsis thaliana, 141.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:195103-195963:+ | gene-YER023W_AKU4011 | rna-NM_001178914.3_AKU4011 | cds-NP_010940.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:230120-230980:- | gene-YER023W_BG1 | rna-NM_001178914.3_BG1 | cds-NP_010940.3_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:202968-203828:+ | gene-YER023W_Bruggeman | rna-NM_001178914.3_Bruggeman | cds-NP_010940.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:197860-198720:+ | gene-YER023W_CAT1 | rna-NM_001178914.3_CAT1 | cds-NP_010940.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:195026-195886:+ | gene-YER023W_CBS1585 | rna-NM_001178914.3_CBS1585 | cds-NP_010940.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:196617-197477:+ | gene-YER023W_CBS436 | rna-NM_001178914.3_CBS436 | cds-NP_010940.3_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:195270-196130:+ | gene-YER023W_CBS6412 | rna-NM_001178914.3_CBS6412 | cds-NP_010940.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:200056-200916:+ | gene-YER023W_CBS6413 | rna-NM_001178914.3_CBS6413 | cds-NP_010940.3_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:199015-199875:+ | gene-YER023W_CENPK1137D | rna-NM_001178914.3_CENPK1137D | cds-NP_010940.3_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:195734-196594:+ | gene-YER023W_EthanolRed | rna-NM_001178914.3_EthanolRed | cds-NP_010940.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:195999-196859:+ | gene-YER023W_FaliES1 | rna-NM_001178914.3_FaliES1 | cds-NP_010940.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000024.1:62652-63512:+ | gene-YER023W_JAY291 | rna-NM_001178914.3_JAY291 | cds-NP_010940.3_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:199172-200032:+ | gene-YER023W_MUCL30387 | rna-NM_001178914.3_MUCL30387 | cds-NP_010940.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:195407-196267:+ | gene-YER023W_MUCL30388 | rna-NM_001178914.3_MUCL30388 | cds-NP_010940.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:194070-194930:+ | gene-YER023W_MUCL39482 | rna-NM_001178914.3_MUCL39482 | cds-NP_010940.3_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:201158-202018:+ | gene-YER023W_MUCL42920 | rna-NM_001178914.3_MUCL42920 | cds-NP_010940.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:201075-201935:+ | gene-YER023W_NCIM3186 | rna-NM_001178914.3_NCIM3186 | cds-NP_010940.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:199141-200001:+ | gene-YER023W_NCYC1407 | rna-NM_001178914.3_NCYC1407 | cds-NP_010940.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:203461-204321:+ | gene-YER023W_PE2H3 | rna-NM_001178914.3_PE2H3 | cds-NP_010940.3_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:199365-200225:+ | gene-YER023W_PE2H4 | rna-NM_001178914.3_PE2H4 | cds-NP_010940.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:201076-201936:+ | gene-YER023W_S288C | rna-NM_001178914.3_S288C | cds-NP_010940.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000020.1:41746-42606:- | gene-YER023W_SA1 | rna-NM_001178914.3_SA1 | cds-NP_010940.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:196770-197630:+ | gene-YER023W_ThermosaccDry | rna-NM_001178914.3_ThermosaccDry | cds-NP_010940.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:195521-196381:+ | gene-YER023W_VR1 | rna-NM_001178914.3_VR1 | cds-NP_010940.3_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:193981-194841:+ | gene-YER023W_ZTW1 | rna-NM_001178914.3_ZTW1 | cds-NP_010940.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:197693-198553:+ | gene-YER023W_Sparadoxus | rna-NM_001178914.3_Sparadoxus | cds-NP_010940.3_Sparadoxus | 93.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |