Gene name: PRO2
Reference locus (S288C): YOR323C
Gene biotype: protein_coding
Description: Glutamate-5-semialdehyde dehydrogenase; Gamma-glutamyl phosphate reductase; catalyzes the second step in proline biosynthesis
Top 10 interactors (score): PRO1 (0.999); CAR2 (0.998); PRO3 (0.997); PUT2 (0.994); YHR033W (0.988); TRP5 (0.962); ARG5,6 (0.942); PUT1 (0.924); GLN1 (0.921); GLT1 (0.896); PTC6 (0.882); GDH1 (0.875); GDH2 (0.863); GDH3 (0.855); GAD1 (0.845); ARG7 (0.796); GCN4 (0.786); ARG3 (0.783); TRP3 (0.779); LDS1 (0.77)
Homologues (species, bitscore): ALDH18A1 (Homo sapiens, 317.4); Aldh18a1 (Mus musculus, 317.0); aldh18a1 (Danio rerio, 330.5); aldh18a1 (Xenopus tropicalis, 323.6); CG7470 (Drosophila melanogaster, 328.2); alh-13 (Caenorhabditis elegans, 307.8); P5CS1 (Arabidopsis thaliana, 346.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:912026-913396:- | gene-YOR323C_AKU4011 | rna-NM_001183743.1_AKU4011 | cds-NP_014968.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:314030-315400:- | gene-YOR323C_BG1 | rna-NM_001183743.1_BG1 | cds-NP_014968.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:897435-898805:- | gene-YOR323C_Bruggeman | rna-NM_001183743.1_Bruggeman | cds-NP_014968.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:898146-899516:- | gene-YOR323C_CAT1 | rna-NM_001183743.1_CAT1 | cds-NP_014968.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:895846-897216:- | gene-YOR323C_CBS1585 | rna-NM_001183743.1_CBS1585 | cds-NP_014968.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:893670-895040:- | gene-YOR323C_CBS436 | rna-NM_001183743.1_CBS436 | cds-NP_014968.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:891556-892926:- | gene-YOR323C_CBS6412 | rna-NM_001183743.1_CBS6412 | cds-NP_014968.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:900684-902054:- | gene-YOR323C_CBS6413 | rna-NM_001183743.1_CBS6413 | cds-NP_014968.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:921311-922681:- | gene-YOR323C_CENPK1137D | rna-NM_001183743.1_CENPK1137D | cds-NP_014968.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:887940-889310:- | gene-YOR323C_EthanolRed | rna-NM_001183743.1_EthanolRed | cds-NP_014968.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:893563-894933:- | gene-YOR323C_FaliES1 | rna-NM_001183743.1_FaliES1 | cds-NP_014968.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:108334-109704:+ | gene-YOR323C_JAY291 | rna-NM_001183743.1_JAY291 | cds-NP_014968.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:901674-903044:- | gene-YOR323C_MUCL30387 | rna-NM_001183743.1_MUCL30387 | cds-NP_014968.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:909687-911057:- | gene-YOR323C_MUCL30388 | rna-NM_001183743.1_MUCL30388 | cds-NP_014968.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:902391-903761:- | gene-YOR323C_MUCL39482 | rna-NM_001183743.1_MUCL39482 | cds-NP_014968.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:911856-913226:- | gene-YOR323C_MUCL42920 | rna-NM_001183743.1_MUCL42920 | cds-NP_014968.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:921424-922794:- | gene-YOR323C_NCIM3186 | rna-NM_001183743.1_NCIM3186 | cds-NP_014968.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:903392-904762:- | gene-YOR323C_NCYC1407 | rna-NM_001183743.1_NCYC1407 | cds-NP_014968.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:901611-902981:- | gene-YOR323C_PE2H3 | rna-NM_001183743.1_PE2H3 | cds-NP_014968.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:917963-919333:- | gene-YOR323C_PE2H4 | rna-NM_001183743.1_PE2H4 | cds-NP_014968.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:921535-922905:- | gene-YOR323C_S288C | rna-NM_001183743.1_S288C | cds-NP_014968.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000016.1:31862-33232:- | gene-YOR323C_SA1 | rna-NM_001183743.1_SA1 | cds-NP_014968.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:892746-894116:- | gene-YOR323C_ThermosaccDry | rna-NM_001183743.1_ThermosaccDry | cds-NP_014968.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:956031-957401:- | gene-YOR323C_VR1 | rna-NM_001183743.1_VR1 | cds-NP_014968.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:625619-626989:- | gene-YOR323C_ZTW1 | rna-NM_001183743.1_ZTW1 | cds-NP_014968.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:899972-901342:- | gene-YOR323C_Sparadoxus | rna-NM_001183743.1_Sparadoxus | cds-NP_014968.1_Sparadoxus | 90.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |