Gene name: PRK1
Reference locus (S288C): YIL095W
Gene biotype: protein_coding
Description: Actin-regulating kinase PRK1; Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication
Top 10 interactors (score): ABP1 (0.997); PAN1 (0.996); EDE1 (0.982); SLA2 (0.98); END3 (0.98); SLA1 (0.972); ARP2 (0.957); YAP1801 (0.956); APM4 (0.933); SWA2 (0.924); APL3 (0.906); CHC1 (0.891); YAP1802 (0.889); APS2 (0.879); ENT1 (0.877); SCD5 (0.875); CLC1 (0.857); LAS17 (0.851); INP52 (0.846); ACT1 (0.82)
Homologues (species, bitscore): AAK1 (Homo sapiens, 223.4); Aak1 (Mus musculus, 221.1); aak1a (Danio rerio, 221.9); aak1 (Xenopus tropicalis, 224.6); Nak (Drosophila melanogaster, 201.1); sel-5 (Caenorhabditis elegans, 169.1); AT2G32850 (Arabidopsis thaliana, 183.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:185366-187798:+ | gene-YIL095W_AKU4011 | rna-NM_001179443.1_AKU4011 | cds-NP_012171.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:48349-50781:+ | gene-YIL095W_BG1 | rna-NM_001179443.1_BG1 | cds-NP_012171.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:190067-192499:+ | gene-YIL095W_Bruggeman | rna-NM_001179443.1_Bruggeman | cds-NP_012171.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:182117-184549:+ | gene-YIL095W_CAT1 | rna-NM_001179443.1_CAT1 | cds-NP_012171.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:185622-188054:+ | gene-YIL095W_CBS1585 | rna-NM_001179443.1_CBS1585 | cds-NP_012171.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:176606-179038:+ | gene-YIL095W_CBS436 | rna-NM_001179443.1_CBS436 | cds-NP_012171.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:183002-185434:+ | gene-YIL095W_CBS6412 | rna-NM_001179443.1_CBS6412 | cds-NP_012171.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:176655-179087:+ | gene-YIL095W_CBS6413 | rna-NM_001179443.1_CBS6413 | cds-NP_012171.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:175646-178078:+ | gene-YIL095W_CENPK1137D | rna-NM_001179443.1_CENPK1137D | cds-NP_012171.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:170585-173017:+ | gene-YIL095W_EthanolRed | rna-NM_001179443.1_EthanolRed | cds-NP_012171.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:186580-189012:+ | gene-YIL095W_FaliES1 | rna-NM_001179443.1_FaliES1 | cds-NP_012171.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000025.1:39453-41885:- | gene-YIL095W_JAY291 | rna-NM_001179443.1_JAY291 | cds-NP_012171.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:187792-190224:+ | gene-YIL095W_MUCL30387 | rna-NM_001179443.1_MUCL30387 | cds-NP_012171.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:185583-188015:+ | gene-YIL095W_MUCL30388 | rna-NM_001179443.1_MUCL30388 | cds-NP_012171.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:186469-188901:+ | gene-YIL095W_MUCL39482 | rna-NM_001179443.1_MUCL39482 | cds-NP_012171.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:189717-192149:+ | gene-YIL095W_MUCL42920 | rna-NM_001179443.1_MUCL42920 | cds-NP_012171.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:183937-186369:+ | gene-YIL095W_NCIM3186 | rna-NM_001179443.1_NCIM3186 | cds-NP_012171.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:190513-192945:+ | gene-YIL095W_NCYC1407 | rna-NM_001179443.1_NCYC1407 | cds-NP_012171.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:185074-187506:+ | gene-YIL095W_PE2H3 | rna-NM_001179443.1_PE2H3 | cds-NP_012171.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:179025-181457:+ | gene-YIL095W_PE2H4 | rna-NM_001179443.1_PE2H4 | cds-NP_012171.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:183937-186369:+ | gene-YIL095W_S288C | rna-NM_001179443.1_S288C | cds-NP_012171.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000111.1:18918-21350:- | gene-YIL095W_SA1 | rna-NM_001179443.1_SA1 | cds-NP_012171.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:185249-187681:+ | gene-YIL095W_ThermosaccDry | rna-NM_001179443.1_ThermosaccDry | cds-NP_012171.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:182929-185361:+ | gene-YIL095W_VR1 | rna-NM_001179443.1_VR1 | cds-NP_012171.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:160182-162614:+ | gene-YIL095W_ZTW1 | rna-NM_001179443.1_ZTW1 | cds-NP_012171.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:184085-186517:+ | gene-YIL095W_Sparadoxus | rna-NM_001179443.1_Sparadoxus | cds-NP_012171.1_Sparadoxus | 87.1 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |