PRE6 (YOL038W)


Gene profile

Gene name: PRE6
Reference locus (S288C): YOL038W
Gene biotype: protein_coding

Description: Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress; Belongs to the peptidase T1A family

Top 10 interactors (score): PRE10 (0.999); RPT5 (0.999); SCL1 (0.999); RPN1 (0.999); PRE5 (0.999); RPT2 (0.999); RPN10 (0.999); RPN11 (0.999); PRE9 (0.999); BLM10 (0.999); PUP2 (0.999); UBP6 (0.999); RPN9 (0.999); RPN8 (0.999); PUP1 (0.999); RPN7 (0.999); PRE3 (0.999); RPN12 (0.999); PRE2 (0.999); RPN5 (0.999)

Homologues (species, bitscore): PSMA7 (Homo sapiens, 302.0); Psma7 (Mus musculus, 300.8); psma8 (Danio rerio, 305.8); psma7 (Xenopus tropicalis, 293.9); Prosalpha4 (Drosophila melanogaster, 275.8); pas-4 (Caenorhabditis elegans, 261.5); PAD1 (Arabidopsis thaliana, 300.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:239701-240465:+ gene-YOL038W_AKU4011 rna-NM_001183292.1_AKU4011 cds-NP_014604.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:55319-56083:+ gene-YOL038W_BG1 rna-NM_001183292.1_BG1 cds-NP_014604.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:242554-243318:+ gene-YOL038W_Bruggeman rna-NM_001183292.1_Bruggeman cds-NP_014604.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:240415-241179:+ gene-YOL038W_CAT1 rna-NM_001183292.1_CAT1 cds-NP_014604.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:234371-235135:+ gene-YOL038W_CBS1585 rna-NM_001183292.1_CBS1585 cds-NP_014604.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:238647-239411:+ gene-YOL038W_CBS436 rna-NM_001183292.1_CBS436 cds-NP_014604.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:233735-234499:+ gene-YOL038W_CBS6412 rna-NM_001183292.1_CBS6412 cds-NP_014604.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:241254-242018:+ gene-YOL038W_CBS6413 rna-NM_001183292.1_CBS6413 cds-NP_014604.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:255038-255802:+ gene-YOL038W_CENPK1137D rna-NM_001183292.1_CENPK1137D cds-NP_014604.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:236688-237452:+ gene-YOL038W_EthanolRed rna-NM_001183292.1_EthanolRed cds-NP_014604.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:239604-240368:+ gene-YOL038W_FaliES1 rna-NM_001183292.1_FaliES1 cds-NP_014604.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000018.1:26092-26856:- gene-YOL038W_JAY291 rna-NM_001183292.1_JAY291 cds-NP_014604.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:245576-246340:+ gene-YOL038W_MUCL30387 rna-NM_001183292.1_MUCL30387 cds-NP_014604.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:249928-250692:+ gene-YOL038W_MUCL30388 rna-NM_001183292.1_MUCL30388 cds-NP_014604.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:241856-242620:+ gene-YOL038W_MUCL39482 rna-NM_001183292.1_MUCL39482 cds-NP_014604.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:256788-257552:+ gene-YOL038W_MUCL42920 rna-NM_001183292.1_MUCL42920 cds-NP_014604.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:255226-255990:+ gene-YOL038W_NCIM3186 rna-NM_001183292.1_NCIM3186 cds-NP_014604.1_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:248596-249360:+ gene-YOL038W_NCYC1407 rna-NM_001183292.1_NCYC1407 cds-NP_014604.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:231013-231777:+ gene-YOL038W_PE2H3 rna-NM_001183292.1_PE2H3 cds-NP_014604.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:241987-242751:+ gene-YOL038W_PE2H4 rna-NM_001183292.1_PE2H4 cds-NP_014604.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:255337-256101:+ gene-YOL038W_S288C rna-NM_001183292.1_S288C cds-NP_014604.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:223337-224101:+ gene-YOL038W_SA1 rna-NM_001183292.1_SA1 cds-NP_014604.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:238175-238939:+ gene-YOL038W_ThermosaccDry rna-NM_001183292.1_ThermosaccDry cds-NP_014604.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:238238-239002:+ gene-YOL038W_VR1 rna-NM_001183292.1_VR1 cds-NP_014604.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000031.1:238040-238804:+ gene-YOL038W_ZTW1 rna-NM_001183292.1_ZTW1 cds-NP_014604.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:246434-247198:+ gene-YOL038W_Sparadoxus rna-NM_001183292.1_Sparadoxus cds-NP_014604.1_Sparadoxus 93.3 100.0 Verified 1 1 1 False True False False False

Additional files