Gene name: PRD1
Reference locus (S288C): YCL057W
Gene biotype: protein_coding
Description: Saccharolysin; Zinc metalloendopeptidase; found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): LAP3 (0.836); CYM1 (0.827); SKP1 (0.786); YCR061W (0.709); TMA108 (0.679); RSF1 (0.653); POT1 (0.622); ALO1 (0.616); PCS60 (0.606); HUL4 (0.605); PRE5 (0.604); HSP10 (0.597); HOT13 (0.594); FAA2 (0.592); SEA4 (0.568); YFR006W (0.559); MCK1 (0.54); DUT1 (0.538); ATP23 (0.531); AAT2 (0.529)
Homologues (species, bitscore): THOP1 (Homo sapiens, 448.7); Thop1 (Mus musculus, 450.7); zgc:92139 (Danio rerio, 454.5); thop1 (Xenopus tropicalis, 444.5); CG7791 (Drosophila melanogaster, 175.3); Y67H2A.7 (Caenorhabditis elegans, 111.3); AT1G67690 (Arabidopsis thaliana, 260.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:26061-28199:+ | gene-YCL057W_AKU4011 | rna-NM_001178701.1_AKU4011 | cds-NP_009874.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000090.1:10976-13114:+ | gene-YCL057W_BG1 | rna-NM_001178701.1_BG1 | cds-NP_009874.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:13476-15614:+ | gene-YCL057W_Bruggeman | rna-NM_001178701.1_Bruggeman | cds-NP_009874.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:25946-28084:+ | gene-YCL057W_CAT1 | rna-NM_001178701.1_CAT1 | cds-NP_009874.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:26746-28884:+ | gene-YCL057W_CBS1585 | rna-NM_001178701.1_CBS1585 | cds-NP_009874.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:25292-27430:+ | gene-YCL057W_CBS436 | rna-NM_001178701.1_CBS436 | cds-NP_009874.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:14505-16643:+ | gene-YCL057W_CBS6412 | rna-NM_001178701.1_CBS6412 | cds-NP_009874.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:25518-27656:+ | gene-YCL057W_CBS6413 | rna-NM_001178701.1_CBS6413 | cds-NP_009874.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:24362-26500:+ | gene-YCL057W_CENPK1137D | rna-NM_001178701.1_CENPK1137D | cds-NP_009874.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:24294-26432:+ | gene-YCL057W_EthanolRed | rna-NM_001178701.1_EthanolRed | cds-NP_009874.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:25056-27194:+ | gene-YCL057W_FaliES1 | rna-NM_001178701.1_FaliES1 | cds-NP_009874.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000225.1:57140-59278:- | gene-YCL057W_JAY291 | rna-NM_001178701.1_JAY291 | cds-NP_009874.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:12481-14619:+ | gene-YCL057W_MUCL30387 | rna-NM_001178701.1_MUCL30387 | cds-NP_009874.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:12773-14911:+ | gene-YCL057W_MUCL30388 | rna-NM_001178701.1_MUCL30388 | cds-NP_009874.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:27130-29268:+ | gene-YCL057W_MUCL39482 | rna-NM_001178701.1_MUCL39482 | cds-NP_009874.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:13053-15191:+ | gene-YCL057W_MUCL42920 | rna-NM_001178701.1_MUCL42920 | cds-NP_009874.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:24400-26538:+ | gene-YCL057W_NCIM3186 | rna-NM_001178701.1_NCIM3186 | cds-NP_009874.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:27458-29596:+ | gene-YCL057W_NCYC1407 | rna-NM_001178701.1_NCYC1407 | cds-NP_009874.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:25228-27366:+ | gene-YCL057W_PE2H3 | rna-NM_001178701.1_PE2H3 | cds-NP_009874.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:25185-27323:+ | gene-YCL057W_PE2H4 | rna-NM_001178701.1_PE2H4 | cds-NP_009874.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:24768-26906:+ | gene-YCL057W_S288C | rna-NM_001178701.1_S288C | cds-NP_009874.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000061.1:11920-14058:+ | gene-YCL057W_SA1 | rna-NM_001178701.1_SA1 | cds-NP_009874.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:25375-27513:+ | gene-YCL057W_ThermosaccDry | rna-NM_001178701.1_ThermosaccDry | cds-NP_009874.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:30663-32801:+ | gene-YCL057W_VR1 | rna-NM_001178701.1_VR1 | cds-NP_009874.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:25601-27739:+ | gene-YCL057W_ZTW1 | rna-NM_001178701.1_ZTW1 | cds-NP_009874.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:55295-57433:+ | gene-YCL057W_Sparadoxus | rna-NM_001178701.1_Sparadoxus | cds-NP_009874.1_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |