Gene name: PPT1
Reference locus (S288C): YGR123C
Gene biotype: protein_coding
Description: Protein serine/threonine phosphatase; regulates Hsp90 chaperone by affecting its ATPase and cochaperone binding activities; has similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth
Top 10 interactors (score): HSC82 (0.999); HSP82 (0.999); SBA1 (0.974); CMD1 (0.921); AHA1 (0.9); PPT2 (0.894); CDC37 (0.881); CPR6 (0.775); RTS1 (0.771); HCH1 (0.75); TPD3 (0.726); HSF1 (0.718); SIS1 (0.713); NGL3 (0.697); LIA1 (0.677); PTC7 (0.671); MLC2 (0.671); MLC1 (0.671); SHE4 (0.64); BMH2 (0.626)
Homologues (species, bitscore): PPP5C (Homo sapiens, 373.6); Ppp5c (Mus musculus, 373.2); ppp5c (Danio rerio, 394.8); ppp5c (Xenopus tropicalis, 365.9); PpD3 (Drosophila melanogaster, 385.2); pph-5 (Caenorhabditis elegans, 355.9); PP5.2 (Arabidopsis thaliana, 369.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:715660-717201:- | gene-YGR123C_AKU4011 | rna-NM_001181252.3_AKU4011 | cds-NP_011639.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000112.1:161-1702:- | gene-YGR123C_BG1 | rna-NM_001181252.3_BG1 | cds-NP_011639.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:718448-719989:- | gene-YGR123C_Bruggeman | rna-NM_001181252.3_Bruggeman | cds-NP_011639.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:717125-718666:- | gene-YGR123C_CAT1 | rna-NM_001181252.3_CAT1 | cds-NP_011639.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:716642-718183:- | gene-YGR123C_CBS1585 | rna-NM_001181252.3_CBS1585 | cds-NP_011639.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:720023-721564:- | gene-YGR123C_CBS436 | rna-NM_001181252.3_CBS436 | cds-NP_011639.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:708318-709859:- | gene-YGR123C_CBS6412 | rna-NM_001181252.3_CBS6412 | cds-NP_011639.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:713252-714793:- | gene-YGR123C_CBS6413 | rna-NM_001181252.3_CBS6413 | cds-NP_011639.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:736379-737920:- | gene-YGR123C_CENPK1137D | rna-NM_001181252.3_CENPK1137D | cds-NP_011639.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:702680-704221:- | gene-YGR123C_EthanolRed | rna-NM_001181252.3_EthanolRed | cds-NP_011639.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:706540-708081:- | gene-YGR123C_FaliES1 | rna-NM_001181252.3_FaliES1 | cds-NP_011639.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000305.1:25767-27308:+ | gene-YGR123C_JAY291 | rna-NM_001181252.3_JAY291 | cds-NP_011639.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:825624-827165:- | gene-YGR123C_MUCL30387 | rna-NM_001181252.3_MUCL30387 | cds-NP_011639.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:717975-719516:- | gene-YGR123C_MUCL30388 | rna-NM_001181252.3_MUCL30388 | cds-NP_011639.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:712368-713909:- | gene-YGR123C_MUCL39482 | rna-NM_001181252.3_MUCL39482 | cds-NP_011639.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:722468-724009:- | gene-YGR123C_MUCL42920 | rna-NM_001181252.3_MUCL42920 | cds-NP_011639.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:736662-738203:- | gene-YGR123C_NCIM3186 | rna-NM_001181252.3_NCIM3186 | cds-NP_011639.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:707069-708610:- | gene-YGR123C_NCYC1407 | rna-NM_001181252.3_NCYC1407 | cds-NP_011639.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:726901-728442:- | gene-YGR123C_PE2H3 | rna-NM_001181252.3_PE2H3 | cds-NP_011639.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:732011-733552:- | gene-YGR123C_PE2H4 | rna-NM_001181252.3_PE2H4 | cds-NP_011639.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:736662-738203:- | gene-YGR123C_S288C | rna-NM_001181252.3_S288C | cds-NP_011639.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:157667-159208:- | gene-YGR123C_SA1 | rna-NM_001181252.3_SA1 | cds-NP_011639.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:727168-728709:- | gene-YGR123C_ThermosaccDry | rna-NM_001181252.3_ThermosaccDry | cds-NP_011639.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:830673-832214:- | gene-YGR123C_VR1 | rna-NM_001181252.3_VR1 | cds-NP_011639.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:29313-30854:- | gene-YGR123C_ZTW1 | rna-NM_001181252.3_ZTW1 | cds-NP_011639.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:716861-718402:- | gene-YGR123C_Sparadoxus | rna-NM_001181252.3_Sparadoxus | cds-NP_011639.3_Sparadoxus | 91.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |