PPR1 (YLR014C)


Gene profile

Gene name: PPR1
Reference locus (S288C): YLR014C
Gene biotype: protein_coding

Description: Pyrimidine pathway regulatory protein 1; Zinc finger transcription factor; contains a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of URA1, URA3, URA4, and URA10, which are involved in de novo pyrimidine biosynthesis, in response to pyrimidine starvation; activity may be modulated by interaction with Tup1p

Top 10 interactors (score): URA4 (0.994); URA5 (0.988); URA1 (0.98); URA2 (0.917); URA10 (0.916); URA3 (0.909); PML39 (0.872); BRE2 (0.759); GAL4 (0.745); LEU3 (0.741); IML2 (0.684); MCH5 (0.626); AIM18 (0.618); SIR3 (0.594); YPR089W (0.582); AZF1 (0.582); GAT1 (0.569); CTS2 (0.566); YER039C-A (0.564); UGA3 (0.562)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:160203-162917:- gene-YLR014C_AKU4011 rna-NM_001181901.1_AKU4011 cds-NP_013114.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:123478-126192:- gene-YLR014C_BG1 rna-NM_001181901.1_BG1 cds-NP_013114.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:170604-173318:- gene-YLR014C_Bruggeman rna-NM_001181901.1_Bruggeman cds-NP_013114.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:170924-173638:- gene-YLR014C_CAT1 rna-NM_001181901.1_CAT1 cds-NP_013114.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:167831-170545:- gene-YLR014C_CBS1585 rna-NM_001181901.1_CBS1585 cds-NP_013114.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:158465-161179:- gene-YLR014C_CBS436 rna-NM_001181901.1_CBS436 cds-NP_013114.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:166292-168952:- gene-YLR014C_CBS6412 rna-NM_001181901.1_CBS6412 cds-NP_013114.1_CBS6412 96.4 97.7 Unannotated 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:168092-170806:- gene-YLR014C_CBS6413 rna-NM_001181901.1_CBS6413 cds-NP_013114.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:157518-160232:- gene-YLR014C_CENPK1137D rna-NM_001181901.1_CENPK1137D cds-NP_013114.1_CENPK1137D 99.8 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:160216-162930:- gene-YLR014C_EthanolRed rna-NM_001181901.1_EthanolRed cds-NP_013114.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:159787-162501:- gene-YLR014C_FaliES1 rna-NM_001181901.1_FaliES1 cds-NP_013114.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000431.1:3983-6697:- gene-YLR014C_JAY291 rna-NM_001181901.1_JAY291 cds-NP_013114.1_JAY291 99.8 100.0 Verified 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:167950-170664:- gene-YLR014C_MUCL30387 rna-NM_001181901.1_MUCL30387 cds-NP_013114.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:173930-176644:- gene-YLR014C_MUCL30388 rna-NM_001181901.1_MUCL30388 cds-NP_013114.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:168326-171040:- gene-YLR014C_MUCL39482 rna-NM_001181901.1_MUCL39482 cds-NP_013114.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:168229-170943:- gene-YLR014C_MUCL42920 rna-NM_001181901.1_MUCL42920 cds-NP_013114.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:172242-174956:- gene-YLR014C_NCIM3186 rna-NM_001181901.1_NCIM3186 cds-NP_013114.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:159946-162660:- gene-YLR014C_NCYC1407 rna-NM_001181901.1_NCYC1407 cds-NP_013114.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:166261-168975:- gene-YLR014C_PE2H3 rna-NM_001181901.1_PE2H3 cds-NP_013114.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:166002-168716:- gene-YLR014C_PE2H4 rna-NM_001181901.1_PE2H4 cds-NP_013114.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:172268-174982:- gene-YLR014C_S288C rna-NM_001181901.1_S288C cds-NP_013114.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000046.1:4118-6832:- gene-YLR014C_SA1 rna-NM_001181901.1_SA1 cds-NP_013114.1_SA1 99.8 100.0 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:160290-163004:- gene-YLR014C_ThermosaccDry rna-NM_001181901.1_ThermosaccDry cds-NP_013114.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:173712-176426:- gene-YLR014C_VR1 rna-NM_001181901.1_VR1 cds-NP_013114.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:159656-162370:- gene-YLR014C_ZTW1 rna-NM_001181901.1_ZTW1 cds-NP_013114.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:168451-171165:- gene-YLR014C_Sparadoxus rna-NM_001181901.1_Sparadoxus cds-NP_013114.1_Sparadoxus 88.3 100.0 Verified 1 1 1 False True False False False

Additional files