Gene name: PPM2
Reference locus (S288C): YOL141W
Gene biotype: protein_coding
Description: tRNA wybutosine-synthesizing protein 4; AdoMet-dependent tRNA methyltransferase; also involved in methoxycarbonylation; required for the synthesis of wybutosine (yW), a modified guanosine found at the 3'-position adjacent to the anticodon of phe-tRNA; similarity to Ppm1p
Top 10 interactors (score): TYW3 (0.999); TYW1 (0.995); TRM5 (0.993); TRM12 (0.986); PPE1 (0.894); CDC55 (0.887); PPH21 (0.886); PPH22 (0.885); PPH3 (0.866); TPD3 (0.858); TRM9 (0.825); PPG1 (0.803); YNL217W (0.77); YML089C (0.75); YOR289W (0.712); JHD1 (0.67); TRM112 (0.643); MGT1 (0.614); MCP1 (0.613); TRM3 (0.605)
Homologues (species, bitscore): LCMT2 (Homo sapiens, 151.4); Lcmt2 (Mus musculus, 136.7); lcmt2 (Danio rerio, 132.9); lcmt1 (Xenopus tropicalis, 87.0); CG3793 (Drosophila melanogaster, 88.6); B0285.4 (Caenorhabditis elegans, 81.6); SBI1 (Arabidopsis thaliana, 110.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:45098-47185:+ | gene-YOL141W_AKU4011 | rna-NM_001183395.2_AKU4011 | cds-NP_014500.2_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:10735-12822:+ | gene-YOL141W_BG1 | rna-NM_001183395.2_BG1 | cds-NP_014500.2_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:46383-48470:+ | gene-YOL141W_Bruggeman | rna-NM_001183395.2_Bruggeman | cds-NP_014500.2_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:45350-47437:+ | gene-YOL141W_CAT1 | rna-NM_001183395.2_CAT1 | cds-NP_014500.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:39582-41669:+ | gene-YOL141W_CBS1585 | rna-NM_001183395.2_CBS1585 | cds-NP_014500.2_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:45438-47525:+ | gene-YOL141W_CBS436 | rna-NM_001183395.2_CBS436 | cds-NP_014500.2_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:39457-41544:+ | gene-YOL141W_CBS6412 | rna-NM_001183395.2_CBS6412 | cds-NP_014500.2_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:45923-48010:+ | gene-YOL141W_CBS6413 | rna-NM_001183395.2_CBS6413 | cds-NP_014500.2_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:56350-58437:+ | gene-YOL141W_CENPK1137D | rna-NM_001183395.2_CENPK1137D | cds-NP_014500.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:43368-45455:+ | gene-YOL141W_EthanolRed | rna-NM_001183395.2_EthanolRed | cds-NP_014500.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:45391-47478:+ | gene-YOL141W_FaliES1 | rna-NM_001183395.2_FaliES1 | cds-NP_014500.2_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000329.1:35078-37165:- | gene-YOL141W_JAY291 | rna-NM_001183395.2_JAY291 | cds-NP_014500.2_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:51004-53091:+ | gene-YOL141W_MUCL30387 | rna-NM_001183395.2_MUCL30387 | cds-NP_014500.2_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:54015-56102:+ | gene-YOL141W_MUCL30388 | rna-NM_001183395.2_MUCL30388 | cds-NP_014500.2_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:47509-49596:+ | gene-YOL141W_MUCL39482 | rna-NM_001183395.2_MUCL39482 | cds-NP_014500.2_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:63409-65496:+ | gene-YOL141W_MUCL42920 | rna-NM_001183395.2_MUCL42920 | cds-NP_014500.2_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:56341-58428:+ | gene-YOL141W_NCIM3186 | rna-NM_001183395.2_NCIM3186 | cds-NP_014500.2_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:53576-55663:+ | gene-YOL141W_NCYC1407 | rna-NM_001183395.2_NCYC1407 | cds-NP_014500.2_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:31974-34061:+ | gene-YOL141W_PE2H3 | rna-NM_001183395.2_PE2H3 | cds-NP_014500.2_PE2H3 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:48922-51009:+ | gene-YOL141W_PE2H4 | rna-NM_001183395.2_PE2H4 | cds-NP_014500.2_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:56452-58539:+ | gene-YOL141W_S288C | rna-NM_001183395.2_S288C | cds-NP_014500.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:29836-31923:+ | gene-YOL141W_SA1 | rna-NM_001183395.2_SA1 | cds-NP_014500.2_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:44534-46621:+ | gene-YOL141W_ThermosaccDry | rna-NM_001183395.2_ThermosaccDry | cds-NP_014500.2_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:45196-47283:+ | gene-YOL141W_VR1 | rna-NM_001183395.2_VR1 | cds-NP_014500.2_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:44290-46377:+ | gene-YOL141W_ZTW1 | rna-NM_001183395.2_ZTW1 | cds-NP_014500.2_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:46784-48871:+ | gene-YOL141W_Sparadoxus | rna-NM_001183395.2_Sparadoxus | cds-NP_014500.2_Sparadoxus | 86.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |