Gene name: PPM1
Reference locus (S288C): YDR435C
Gene biotype: protein_coding
Description: Carboxyl methyltransferase; methylates the C terminus of the protein phosphatase 2A catalytic subunit (Pph21p or Pph22p), which is important for complex formation with regulatory subunits; required for methionine to inhibit autophagy and promote growth
Top 10 interactors (score): PPH21 (0.998); CDC55 (0.997); PPH22 (0.996); TPD3 (0.995); PPH3 (0.991); RRD2 (0.967); RTS1 (0.921); PPG1 (0.918); PPE1 (0.916); RRD1 (0.903); TIP41 (0.901); TYW3 (0.887); SIT4 (0.792); CDC3 (0.786); TAP42 (0.774); YNL217W (0.77); NPR2 (0.754); SAP190 (0.7); TRM5 (0.693); TRM12 (0.664)
Homologues (species, bitscore): LCMT1 (Homo sapiens, 115.2); Lcmt1 (Mus musculus, 113.2); lcmt1 (Danio rerio, 84.3); lcmt1 (Xenopus tropicalis, 76.6); CG3793 (Drosophila melanogaster, 87.8); B0285.4 (Caenorhabditis elegans, 115.5); SBI1 (Arabidopsis thaliana, 105.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1273253-1274239:- | gene-YDR435C_AKU4011 | rna-NM_001180743.1_AKU4011 | cds-NP_010723.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:151591-152577:- | gene-YDR435C_BG1 | rna-NM_001180743.1_BG1 | cds-NP_010723.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1303640-1304626:- | gene-YDR435C_Bruggeman | rna-NM_001180743.1_Bruggeman | cds-NP_010723.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1281829-1282815:- | gene-YDR435C_CAT1 | rna-NM_001180743.1_CAT1 | cds-NP_010723.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1267561-1268547:- | gene-YDR435C_CBS1585 | rna-NM_001180743.1_CBS1585 | cds-NP_010723.1_CBS1585 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1286913-1287899:- | gene-YDR435C_CBS436 | rna-NM_001180743.1_CBS436 | cds-NP_010723.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1263548-1264534:- | gene-YDR435C_CBS6412 | rna-NM_001180743.1_CBS6412 | cds-NP_010723.1_CBS6412 | 98.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1285697-1286683:- | gene-YDR435C_CBS6413 | rna-NM_001180743.1_CBS6413 | cds-NP_010723.1_CBS6413 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1331661-1332647:- | gene-YDR435C_CENPK1137D | rna-NM_001180743.1_CENPK1137D | cds-NP_010723.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1276830-1277816:- | gene-YDR435C_EthanolRed | rna-NM_001180743.1_EthanolRed | cds-NP_010723.1_EthanolRed | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1280137-1281123:- | gene-YDR435C_FaliES1 | rna-NM_001180743.1_FaliES1 | cds-NP_010723.1_FaliES1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000263.1:24395-25381:- | gene-YDR435C_JAY291 | rna-NM_001180743.1_JAY291 | cds-NP_010723.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1287281-1288267:- | gene-YDR435C_MUCL30387 | rna-NM_001180743.1_MUCL30387 | cds-NP_010723.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1269217-1270203:- | gene-YDR435C_MUCL30388 | rna-NM_001180743.1_MUCL30388 | cds-NP_010723.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1259053-1260039:- | gene-YDR435C_MUCL39482 | rna-NM_001180743.1_MUCL39482 | cds-NP_010723.1_MUCL39482 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1201473-1202459:- | gene-YDR435C_MUCL42920 | rna-NM_001180743.1_MUCL42920 | cds-NP_010723.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1332906-1333892:- | gene-YDR435C_NCIM3186 | rna-NM_001180743.1_NCIM3186 | cds-NP_010723.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1272838-1273824:- | gene-YDR435C_NCYC1407 | rna-NM_001180743.1_NCYC1407 | cds-NP_010723.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1283639-1284625:- | gene-YDR435C_PE2H3 | rna-NM_001180743.1_PE2H3 | cds-NP_010723.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1289207-1290193:- | gene-YDR435C_PE2H4 | rna-NM_001180743.1_PE2H4 | cds-NP_010723.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1332983-1333969:- | gene-YDR435C_S288C | rna-NM_001180743.1_S288C | cds-NP_010723.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000082.1:23247-24233:+ | gene-YDR435C_SA1 | rna-NM_001180743.1_SA1 | cds-NP_010723.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1284399-1285385:- | gene-YDR435C_ThermosaccDry | rna-NM_001180743.1_ThermosaccDry | cds-NP_010723.1_ThermosaccDry | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1299620-1300606:- | gene-YDR435C_VR1 | rna-NM_001180743.1_VR1 | cds-NP_010723.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:327040-328026:- | gene-YDR435C_ZTW1 | rna-NM_001180743.1_ZTW1 | cds-NP_010723.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1280795-1281781:- | gene-YDR435C_Sparadoxus | rna-NM_001180743.1_Sparadoxus | cds-NP_010723.1_Sparadoxus | 87.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |