PPE1 (YHR075C)


Gene profile

Gene name: PPE1
Reference locus (S288C): YHR075C
Gene biotype: protein_coding

Description: Protein phosphatase methylesterase 1; Protein with carboxyl methyl esterase activity; may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein; Belongs to the AB hydrolase superfamily

Top 10 interactors (score): PPH22 (0.996); PPH21 (0.996); TPD3 (0.994); RRD1 (0.975); RRD2 (0.975); RSM22 (0.968); MRP17 (0.965); MRPS8 (0.961); MRPS16 (0.943); MRPS17 (0.942); RSM26 (0.923); MRP1 (0.922); MRPS35 (0.918); PPM1 (0.916); NAM9 (0.91); RSM23 (0.909); MRP51 (0.908); MRPS5 (0.908); MRP21 (0.908); PET123 (0.907)

Homologues (species, bitscore): PPME1 (Homo sapiens, 141.7); Ppme1 (Mus musculus, 149.4); ppme1 (Danio rerio, 137.9); ppme1 (Xenopus tropicalis, 142.5); CG5068 (Drosophila melanogaster, 127.9); B0464.9 (Caenorhabditis elegans, 167.9); AT4G10050 (Arabidopsis thaliana, 144.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:234859-236061:- gene-YHR075C_AKU4011 rna-NM_001179205.1_AKU4011 cds-NP_011942.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:155206-156408:- gene-YHR075C_BG1 rna-NM_001179205.1_BG1 cds-NP_011942.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:242686-243888:- gene-YHR075C_Bruggeman rna-NM_001179205.1_Bruggeman cds-NP_011942.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:237331-238533:- gene-YHR075C_CAT1 rna-NM_001179205.1_CAT1 cds-NP_011942.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:233900-235102:- gene-YHR075C_CBS1585 rna-NM_001179205.1_CBS1585 cds-NP_011942.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:231759-232961:- gene-YHR075C_CBS436 rna-NM_001179205.1_CBS436 cds-NP_011942.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:237245-238447:- gene-YHR075C_CBS6412 rna-NM_001179205.1_CBS6412 cds-NP_011942.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:234940-236142:- gene-YHR075C_CBS6413 rna-NM_001179205.1_CBS6413 cds-NP_011942.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:241609-242811:- gene-YHR075C_CENPK1137D rna-NM_001179205.1_CENPK1137D cds-NP_011942.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:294457-295659:- gene-YHR075C_EthanolRed rna-NM_001179205.1_EthanolRed cds-NP_011942.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:235261-236463:- gene-YHR075C_FaliES1 rna-NM_001179205.1_FaliES1 cds-NP_011942.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000394.1:18001-19203:- gene-YHR075C_JAY291 rna-NM_001179205.1_JAY291 cds-NP_011942.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:242196-243398:- gene-YHR075C_MUCL30387 rna-NM_001179205.1_MUCL30387 cds-NP_011942.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:242064-243266:- gene-YHR075C_MUCL30388 rna-NM_001179205.1_MUCL30388 cds-NP_011942.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:234224-235426:- gene-YHR075C_MUCL39482 rna-NM_001179205.1_MUCL39482 cds-NP_011942.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:240963-242165:- gene-YHR075C_MUCL42920 rna-NM_001179205.1_MUCL42920 cds-NP_011942.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:248321-249523:- gene-YHR075C_NCIM3186 rna-NM_001179205.1_NCIM3186 cds-NP_011942.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:236688-237890:- gene-YHR075C_NCYC1407 rna-NM_001179205.1_NCYC1407 cds-NP_011942.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:236365-237567:- gene-YHR075C_PE2H3 rna-NM_001179205.1_PE2H3 cds-NP_011942.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:243812-245014:- gene-YHR075C_PE2H4 rna-NM_001179205.1_PE2H4 cds-NP_011942.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:248439-249641:- gene-YHR075C_S288C rna-NM_001179205.1_S288C cds-NP_011942.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000014.1:109342-110544:+ gene-YHR075C_SA1 rna-NM_001179205.1_SA1 cds-NP_011942.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:236352-237554:- gene-YHR075C_ThermosaccDry rna-NM_001179205.1_ThermosaccDry cds-NP_011942.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:243991-245193:- gene-YHR075C_VR1 rna-NM_001179205.1_VR1 cds-NP_011942.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:227903-229105:- gene-YHR075C_ZTW1 rna-NM_001179205.1_ZTW1 cds-NP_011942.1_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:233728-234927:- gene-YHR075C_Sparadoxus rna-NM_001179205.1_Sparadoxus cds-NP_011942.1_Sparadoxus 89.4 99.5 Verified 1 1 1 False True False False False

Additional files