POP1 (YNL221C)


Gene profile

Gene name: POP1
Reference locus (S288C): YNL221C
Gene biotype: protein_coding

Description: Ribonucleases P/MRP protein subunit POP1; Subunit of RNase MRP, nuclear RNase P and telomerase complexes; RNase MRP cleaves pre-rRNA, nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs, while telomerase replenishes telomeric DNA; binds to the RPR1 RNA subunit in RNase P

Top 10 interactors (score): RMP1 (0.999); POP5 (0.999); POP8 (0.999); POP4 (0.999); RPR2 (0.999); POP7 (0.999); POP6 (0.999); RPP1 (0.999); SNM1 (0.999); POP3 (0.999); SNU13 (0.988); RPM2 (0.979); SEN15 (0.963); SEN34 (0.958); SEN2 (0.955); EST1 (0.951); NOP1 (0.941); EST2 (0.93); EST3 (0.928); LCP5 (0.927)

Homologues (species, bitscore): POP1 (Homo sapiens, 76.3); Pop1 (Mus musculus, 76.3); pop1 (Danio rerio, 61.6); l(1)G0045 (Drosophila melanogaster, 66.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:224849-227476:- gene-YNL221C_AKU4011 rna-NM_001183059.1_AKU4011 cds-NP_014178.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:128792-131419:- gene-YNL221C_BG1 rna-NM_001183059.1_BG1 cds-NP_014178.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:234893-237520:- gene-YNL221C_Bruggeman rna-NM_001183059.1_Bruggeman cds-NP_014178.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:242046-244673:- gene-YNL221C_CAT1 rna-NM_001183059.1_CAT1 cds-NP_014178.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:225244-227871:- gene-YNL221C_CBS1585 rna-NM_001183059.1_CBS1585 cds-NP_014178.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:220324-222951:- gene-YNL221C_CBS436 rna-NM_001183059.1_CBS436 cds-NP_014178.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:221282-223909:- gene-YNL221C_CBS6412 rna-NM_001183059.1_CBS6412 cds-NP_014178.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:221928-224555:- gene-YNL221C_CBS6413 rna-NM_001183059.1_CBS6413 cds-NP_014178.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:224870-227497:- gene-YNL221C_CENPK1137D rna-NM_001183059.1_CENPK1137D cds-NP_014178.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:222484-225111:- gene-YNL221C_EthanolRed rna-NM_001183059.1_EthanolRed cds-NP_014178.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:217226-219853:- gene-YNL221C_FaliES1 rna-NM_001183059.1_FaliES1 cds-NP_014178.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000082.1:128385-131012:- gene-YNL221C_JAY291 rna-NM_001183059.1_JAY291 cds-NP_014178.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:230429-233056:- gene-YNL221C_MUCL30387 rna-NM_001183059.1_MUCL30387 cds-NP_014178.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:229010-231637:- gene-YNL221C_MUCL30388 rna-NM_001183059.1_MUCL30388 cds-NP_014178.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:222734-225361:- gene-YNL221C_MUCL39482 rna-NM_001183059.1_MUCL39482 cds-NP_014178.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:224990-227617:- gene-YNL221C_MUCL42920 rna-NM_001183059.1_MUCL42920 cds-NP_014178.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:231037-233664:- gene-YNL221C_NCIM3186 rna-NM_001183059.1_NCIM3186 cds-NP_014178.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:224824-227451:- gene-YNL221C_NCYC1407 rna-NM_001183059.1_NCYC1407 cds-NP_014178.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:221730-224357:- gene-YNL221C_PE2H3 rna-NM_001183059.1_PE2H3 cds-NP_014178.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:221118-223745:- gene-YNL221C_PE2H4 rna-NM_001183059.1_PE2H4 cds-NP_014178.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:231068-233695:- gene-YNL221C_S288C rna-NM_001183059.1_S288C cds-NP_014178.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000040.1:18615-21242:+ gene-YNL221C_SA1 rna-NM_001183059.1_SA1 cds-NP_014178.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:218082-220709:- gene-YNL221C_ThermosaccDry rna-NM_001183059.1_ThermosaccDry cds-NP_014178.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:237086-239713:- gene-YNL221C_VR1 rna-NM_001183059.1_VR1 cds-NP_014178.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:128413-131040:- gene-YNL221C_ZTW1 rna-NM_001183059.1_ZTW1 cds-NP_014178.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:228499-231126:- gene-YNL221C_Sparadoxus rna-NM_001183059.1_Sparadoxus cds-NP_014178.1_Sparadoxus 86.8 99.8 Mismatch 1 1 1 False True False False False

Additional files