Gene name: POL4
Reference locus (S288C): YCR014C
Gene biotype: protein_coding
Description: DNA polymerase IV; undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta
Top 10 interactors (score): DNL4 (0.997); POL30 (0.991); YKU70 (0.991); RAD27 (0.988); YKU80 (0.965); CDC9 (0.958); LIF1 (0.95); REV1 (0.937); NEJ1 (0.924); TPP1 (0.919); RAD30 (0.916); REV3 (0.911); TDP1 (0.898); EXO1 (0.89); POL3 (0.886); POL2 (0.858); PSO2 (0.847); RAD52 (0.806); APN2 (0.765); RAD18 (0.753)
Homologues (species, bitscore): POLL (Homo sapiens, 103.2); Poll (Mus musculus, 93.2); poll (Danio rerio, 115.2); poll (Xenopus tropicalis, 114.0); AT1G10520 (Arabidopsis thaliana, 79.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:133559-135304:- | gene-YCR014C_AKU4011 | rna-NM_001178727.1_AKU4011 | cds-NP_009940.2_AKU4011 | 99.1 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000178.1:10699-12447:+ | gene-YCR014C_BG1 | rna-NM_001178727.1_BG1 | cds-NP_009940.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:129371-131119:- | gene-YCR014C_Bruggeman | rna-NM_001178727.1_Bruggeman | cds-NP_009940.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:139773-141521:- | gene-YCR014C_CAT1 | rna-NM_001178727.1_CAT1 | cds-NP_009940.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:134209-135954:- | gene-YCR014C_CBS1585 | rna-NM_001178727.1_CBS1585 | cds-NP_009940.2_CBS1585 | 99.1 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:139468-141216:- | gene-YCR014C_CBS436 | rna-NM_001178727.1_CBS436 | cds-NP_009940.2_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:121669-123414:- | gene-YCR014C_CBS6412 | rna-NM_001178727.1_CBS6412 | cds-NP_009940.2_CBS6412 | 99.1 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:133516-135261:- | gene-YCR014C_CBS6413 | rna-NM_001178727.1_CBS6413 | cds-NP_009940.2_CBS6413 | 99.1 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:144663-146410:- | gene-YCR014C_CENPK1137D | rna-NM_001178727.1_CENPK1137D | cds-NP_009940.2_CENPK1137D | 99.9 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:131577-133322:- | gene-YCR014C_EthanolRed | rna-NM_001178727.1_EthanolRed | cds-NP_009940.2_EthanolRed | 99.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:133875-135620:- | gene-YCR014C_FaliES1 | rna-NM_001178727.1_FaliES1 | cds-NP_009940.2_FaliES1 | 99.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000126.1:48045-49793:- | gene-YCR014C_JAY291 | rna-NM_001178727.1_JAY291 | cds-NP_009940.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:127176-128924:- | gene-YCR014C_MUCL30387 | rna-NM_001178727.1_MUCL30387 | cds-NP_009940.2_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:126148-127896:- | gene-YCR014C_MUCL30388 | rna-NM_001178727.1_MUCL30388 | cds-NP_009940.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:134626-136371:- | gene-YCR014C_MUCL39482 | rna-NM_001178727.1_MUCL39482 | cds-NP_009940.2_MUCL39482 | 99.1 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:129861-131609:- | gene-YCR014C_MUCL42920 | rna-NM_001178727.1_MUCL42920 | cds-NP_009940.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:138817-140565:- | gene-YCR014C_NCIM3186 | rna-NM_001178727.1_NCIM3186 | cds-NP_009940.2_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:135357-137102:- | gene-YCR014C_NCYC1407 | rna-NM_001178727.1_NCYC1407 | cds-NP_009940.2_NCYC1407 | 99.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:139304-141052:- | gene-YCR014C_PE2H3 | rna-NM_001178727.1_PE2H3 | cds-NP_009940.2_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:139243-140991:- | gene-YCR014C_PE2H4 | rna-NM_001178727.1_PE2H4 | cds-NP_009940.2_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:139185-140933:- | gene-YCR014C_S288C | rna-NM_001178727.1_S288C | cds-NP_009940.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000073.1:10736-12484:+ | gene-YCR014C_SA1 | rna-NM_001178727.1_SA1 | cds-NP_009940.2_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:134443-136188:- | gene-YCR014C_ThermosaccDry | rna-NM_001178727.1_ThermosaccDry | cds-NP_009940.2_ThermosaccDry | 99.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:145373-147121:- | gene-YCR014C_VR1 | rna-NM_001178727.1_VR1 | cds-NP_009940.2_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:133379-135123:- | gene-YCR014C_ZTW1 | rna-NM_001178727.1_ZTW1 | cds-NP_009940.2_ZTW1 | 98.9 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:165539-167290:- | gene-YCR014C_Sparadoxus | rna-NM_001178727.1_Sparadoxus | cds-NP_009940.2_Sparadoxus | 86.9 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |