POL30 (YBR088C)


Gene profile

Gene name: POL30
Reference locus (S288C): YBR088C
Gene biotype: protein_coding

Description: Proliferating cell nuclear antigen (PCNA); functions as the sliding replication clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair; PCNA ubiquitination at K164 plays a crucial role during Okazaki fragment processing

Top 10 interactors (score): POL3 (0.999); RFC3 (0.999); UBC9 (0.999); ELG1 (0.999); MSH6 (0.999); POL31 (0.999); RFC2 (0.999); RFA1 (0.999); RFC5 (0.999); RAD27 (0.999); MSH2 (0.999); RFC1 (0.999); CDC9 (0.999); RAD30 (0.999); RAD18 (0.999); RFC4 (0.999); CAC2 (0.999); SRS2 (0.998); SMT3 (0.998); POL1 (0.998)

Homologues (species, bitscore): PCNA (Homo sapiens, 200.7); Pcna-ps2 (Mus musculus, 201.4); pcna (Danio rerio, 190.3); pcna (Xenopus tropicalis, 193.0); PCNA (Drosophila melanogaster, 209.1); pcn-1 (Caenorhabditis elegans, 204.5); PCNA1 (Arabidopsis thaliana, 224.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:407358-408134:- gene-YBR088C_AKU4011 rna-NM_001178436.1_AKU4011 cds-NP_009645.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:398395-399171:- gene-YBR088C_BG1 rna-NM_001178436.1_BG1 cds-NP_009645.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:408933-409709:- gene-YBR088C_Bruggeman rna-NM_001178436.1_Bruggeman cds-NP_009645.1_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:411906-412682:- gene-YBR088C_CAT1 rna-NM_001178436.1_CAT1 cds-NP_009645.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:399643-400419:- gene-YBR088C_CBS1585 rna-NM_001178436.1_CBS1585 cds-NP_009645.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:407764-408540:- gene-YBR088C_CBS436 rna-NM_001178436.1_CBS436 cds-NP_009645.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:497872-498648:- gene-YBR088C_CBS6412 rna-NM_001178436.1_CBS6412 cds-NP_009645.1_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:404783-405559:- gene-YBR088C_CBS6413 rna-NM_001178436.1_CBS6413 cds-NP_009645.1_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:418742-419518:- gene-YBR088C_CENPK1137D rna-NM_001178436.1_CENPK1137D cds-NP_009645.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:534150-534926:- gene-YBR088C_EthanolRed rna-NM_001178436.1_EthanolRed cds-NP_009645.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:423433-424209:- gene-YBR088C_FaliES1 rna-NM_001178436.1_FaliES1 cds-NP_009645.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000013.1:2972-3748:+ gene-YBR088C_JAY291 rna-NM_001178436.1_JAY291 cds-NP_009645.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:411170-411946:- gene-YBR088C_MUCL30387 rna-NM_001178436.1_MUCL30387 cds-NP_009645.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:410165-410941:- gene-YBR088C_MUCL30388 rna-NM_001178436.1_MUCL30388 cds-NP_009645.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:399634-400410:- gene-YBR088C_MUCL39482 rna-NM_001178436.1_MUCL39482 cds-NP_009645.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:406847-407623:- gene-YBR088C_MUCL42920 rna-NM_001178436.1_MUCL42920 cds-NP_009645.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:424787-425563:- gene-YBR088C_NCIM3186 rna-NM_001178436.1_NCIM3186 cds-NP_009645.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:400566-401342:- gene-YBR088C_NCYC1407 rna-NM_001178436.1_NCYC1407 cds-NP_009645.1_NCYC1407 99.6 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:413182-413958:- gene-YBR088C_PE2H3 rna-NM_001178436.1_PE2H3 cds-NP_009645.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:410858-411634:- gene-YBR088C_PE2H4 rna-NM_001178436.1_PE2H4 cds-NP_009645.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:424990-425766:- gene-YBR088C_S288C rna-NM_001178436.1_S288C cds-NP_009645.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000017.1:51939-52715:+ gene-YBR088C_SA1 rna-NM_001178436.1_SA1 cds-NP_009645.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:422440-423216:- gene-YBR088C_ThermosaccDry rna-NM_001178436.1_ThermosaccDry cds-NP_009645.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:404444-405220:- gene-YBR088C_VR1 rna-NM_001178436.1_VR1 cds-NP_009645.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:398105-398881:- gene-YBR088C_ZTW1 rna-NM_001178436.1_ZTW1 cds-NP_009645.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:434958-435734:- gene-YBR088C_Sparadoxus rna-NM_001178436.1_Sparadoxus cds-NP_009645.1_Sparadoxus 92.2 100.0 Verified 1 1 1 True True False False False

Additional files