Gene name: POL2
Reference locus (S288C): YNL262W
Gene biotype: protein_coding
Description: Catalytic subunit of DNA polymerase (II) epsilon; a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; participates in leading-strand synthesis during DNA replication; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p; Belongs to the DNA polymerase type-B family
Top 10 interactors (score): MCM2 (0.999); CDC45 (0.999); MCM7 (0.999); PRI1 (0.999); DPB3 (0.999); MCM6 (0.999); DPB4 (0.999); POL1 (0.999); DPB2 (0.999); POL3 (0.999); MCM3 (0.999); MCM5 (0.999); PRI2 (0.999); POL31 (0.999); POL12 (0.999); MCM4 (0.999); CTF18 (0.999); REV3 (0.998); CTF4 (0.998); MSH2 (0.998)
Homologues (species, bitscore): POLE (Homo sapiens, 1649.8); Pole (Mus musculus, 1656.3); pole (Danio rerio, 1666.4); pole (Xenopus tropicalis, 1641.7); DNApol-epsilon255 (Drosophila melanogaster, 1542.3); F33H2.5 (Caenorhabditis elegans, 1372.8); TIL1 (Arabidopsis thaliana, 1512.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:141987-148655:+ | gene-YNL262W_AKU4011 | rna-NM_001183100.1_AKU4011 | cds-NP_014137.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:45946-52614:+ | gene-YNL262W_BG1 | rna-NM_001183100.1_BG1 | cds-NP_014137.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:151809-158477:+ | gene-YNL262W_Bruggeman | rna-NM_001183100.1_Bruggeman | cds-NP_014137.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:159105-165773:+ | gene-YNL262W_CAT1 | rna-NM_001183100.1_CAT1 | cds-NP_014137.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:142387-149055:+ | gene-YNL262W_CBS1585 | rna-NM_001183100.1_CBS1585 | cds-NP_014137.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:137485-144153:+ | gene-YNL262W_CBS436 | rna-NM_001183100.1_CBS436 | cds-NP_014137.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:138798-145466:+ | gene-YNL262W_CBS6412 | rna-NM_001183100.1_CBS6412 | cds-NP_014137.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:139080-145748:+ | gene-YNL262W_CBS6413 | rna-NM_001183100.1_CBS6413 | cds-NP_014137.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:142032-148700:+ | gene-YNL262W_CENPK1137D | rna-NM_001183100.1_CENPK1137D | cds-NP_014137.1_CENPK1137D | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:139633-146301:+ | gene-YNL262W_EthanolRed | rna-NM_001183100.1_EthanolRed | cds-NP_014137.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:134370-141038:+ | gene-YNL262W_FaliES1 | rna-NM_001183100.1_FaliES1 | cds-NP_014137.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:45544-52212:+ | gene-YNL262W_JAY291 | rna-NM_001183100.1_JAY291 | cds-NP_014137.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:147597-154265:+ | gene-YNL262W_MUCL30387 | rna-NM_001183100.1_MUCL30387 | cds-NP_014137.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:146175-152843:+ | gene-YNL262W_MUCL30388 | rna-NM_001183100.1_MUCL30388 | cds-NP_014137.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:139877-146545:+ | gene-YNL262W_MUCL39482 | rna-NM_001183100.1_MUCL39482 | cds-NP_014137.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:142147-148815:+ | gene-YNL262W_MUCL42920 | rna-NM_001183100.1_MUCL42920 | cds-NP_014137.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:148181-154849:+ | gene-YNL262W_NCIM3186 | rna-NM_001183100.1_NCIM3186 | cds-NP_014137.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:141979-148647:+ | gene-YNL262W_NCYC1407 | rna-NM_001183100.1_NCYC1407 | cds-NP_014137.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:138880-145548:+ | gene-YNL262W_PE2H3 | rna-NM_001183100.1_PE2H3 | cds-NP_014137.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:138268-144936:+ | gene-YNL262W_PE2H4 | rna-NM_001183100.1_PE2H4 | cds-NP_014137.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:148212-154880:+ | gene-YNL262W_S288C | rna-NM_001183100.1_S288C | cds-NP_014137.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:45614-52282:+ | gene-YNL262W_SA1 | rna-NM_001183100.1_SA1 | cds-NP_014137.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:135227-141895:+ | gene-YNL262W_ThermosaccDry | rna-NM_001183100.1_ThermosaccDry | cds-NP_014137.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:154139-160807:+ | gene-YNL262W_VR1 | rna-NM_001183100.1_VR1 | cds-NP_014137.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:45562-52229:+ | gene-YNL262W_ZTW1 | rna-NM_001183100.1_ZTW1 | cds-NP_014137.1_ZTW1 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:145430-152098:+ | gene-YNL262W_Sparadoxus | rna-NM_001183100.1_Sparadoxus | cds-NP_014137.1_Sparadoxus | 91.0 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |