POL12 (YBL035C)


Gene profile

Gene name: POL12
Reference locus (S288C): YBL035C
Gene biotype: protein_coding

Description: B subunit of DNA polymerase alpha-primase complex; required for initiation of DNA replication during mitotic and premeiotic DNA synthesis; also functions in telomere capping and length regulation

Top 10 interactors (score): POL31 (0.999); POL3 (0.999); PRI2 (0.999); MCM4 (0.999); CDC45 (0.999); POL1 (0.999); DPB2 (0.999); PRI1 (0.999); POL2 (0.999); RFA2 (0.998); MCM2 (0.998); MCM5 (0.997); RAD27 (0.997); MCM7 (0.997); ORC4 (0.997); RFA1 (0.997); CDC6 (0.997); POL30 (0.996); MCM3 (0.996); ORC5 (0.996)

Homologues (species, bitscore): POLA2 (Homo sapiens, 152.5); Pola2 (Mus musculus, 150.2); pola2 (Danio rerio, 157.1); pola2 (Xenopus tropicalis, 149.8); CG5923 (Drosophila melanogaster, 101.7); div-1 (Caenorhabditis elegans, 110.2); POLA2 (Arabidopsis thaliana, 144.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:145109-147226:- gene-YBL035C_AKU4011 rna-NM_001178275.1_AKU4011 cds-NP_009518.1_AKU4011 99.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:135927-138044:- gene-YBL035C_BG1 rna-NM_001178275.1_BG1 cds-NP_009518.1_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:145692-147809:- gene-YBL035C_Bruggeman rna-NM_001178275.1_Bruggeman cds-NP_009518.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:148324-150441:- gene-YBL035C_CAT1 rna-NM_001178275.1_CAT1 cds-NP_009518.1_CAT1 99.1 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:137648-139765:- gene-YBL035C_CBS1585 rna-NM_001178275.1_CBS1585 cds-NP_009518.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:146158-148275:- gene-YBL035C_CBS436 rna-NM_001178275.1_CBS436 cds-NP_009518.1_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:236404-238521:- gene-YBL035C_CBS6412 rna-NM_001178275.1_CBS6412 cds-NP_009518.1_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:143219-145336:- gene-YBL035C_CBS6413 rna-NM_001178275.1_CBS6413 cds-NP_009518.1_CBS6413 99.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:145243-147360:- gene-YBL035C_CENPK1137D rna-NM_001178275.1_CENPK1137D cds-NP_009518.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:159068-161185:- gene-YBL035C_EthanolRed rna-NM_001178275.1_EthanolRed cds-NP_009518.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:159915-162032:- gene-YBL035C_FaliES1 rna-NM_001178275.1_FaliES1 cds-NP_009518.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000072.1:62551-64668:- gene-YBL035C_JAY291 rna-NM_001178275.1_JAY291 cds-NP_009518.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:145071-147188:- gene-YBL035C_MUCL30387 rna-NM_001178275.1_MUCL30387 cds-NP_009518.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:146342-148459:- gene-YBL035C_MUCL30388 rna-NM_001178275.1_MUCL30388 cds-NP_009518.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:137823-139940:- gene-YBL035C_MUCL39482 rna-NM_001178275.1_MUCL39482 cds-NP_009518.1_MUCL39482 99.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:144656-146773:- gene-YBL035C_MUCL42920 rna-NM_001178275.1_MUCL42920 cds-NP_009518.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:151290-153407:- gene-YBL035C_NCIM3186 rna-NM_001178275.1_NCIM3186 cds-NP_009518.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:138960-141077:- gene-YBL035C_NCYC1407 rna-NM_001178275.1_NCYC1407 cds-NP_009518.1_NCYC1407 99.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:145228-147345:- gene-YBL035C_PE2H3 rna-NM_001178275.1_PE2H3 cds-NP_009518.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:142872-144989:- gene-YBL035C_PE2H4 rna-NM_001178275.1_PE2H4 cds-NP_009518.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:151493-153610:- gene-YBL035C_S288C rna-NM_001178275.1_S288C cds-NP_009518.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000051.1:36079-38196:- gene-YBL035C_SA1 rna-NM_001178275.1_SA1 cds-NP_009518.1_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:159868-161985:- gene-YBL035C_ThermosaccDry rna-NM_001178275.1_ThermosaccDry cds-NP_009518.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:142057-144174:- gene-YBL035C_VR1 rna-NM_001178275.1_VR1 cds-NP_009518.1_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:136588-138705:- gene-YBL035C_ZTW1 rna-NM_001178275.1_ZTW1 cds-NP_009518.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:171467-173584:- gene-YBL035C_Sparadoxus rna-NM_001178275.1_Sparadoxus cds-NP_009518.1_Sparadoxus 88.5 100.0 Verified 1 1 1 False True False False False

Additional files