POL1 (YNL102W)


Gene profile

Gene name: POL1
Reference locus (S288C): YNL102W
Gene biotype: protein_coding

Description: Dna-directed dna polymerase alpha catalytic subunit pol1; Catalytic subunit of the DNA polymerase I alpha-primase complex; required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis

Top 10 interactors (score): MCM4 (0.999); DPB2 (0.999); MCM2 (0.999); CDC45 (0.999); PRI1 (0.999); POL2 (0.999); CTF4 (0.999); POL12 (0.999); CDC13 (0.999); POL31 (0.999); PRI2 (0.999); MCM3 (0.998); MCM5 (0.998); POL30 (0.998); RFA1 (0.998); CDC6 (0.998); RAD27 (0.998); MCM6 (0.998); MCM10 (0.998); MCM7 (0.997)

Homologues (species, bitscore): POLA1 (Homo sapiens, 685.6); Pola1 (Mus musculus, 678.7); pola1 (Danio rerio, 695.7); pola1 (Xenopus tropicalis, 684.5); POLA (Drosophila melanogaster, 585.1); Y47D3A.29 (Caenorhabditis elegans, 562.8); ICU2 (Arabidopsis thaliana, 582.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:423753-428159:+ gene-YNL102W_AKU4011 rna-NM_001182940.3_AKU4011 cds-NP_014297.3_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:327750-332156:+ gene-YNL102W_BG1 rna-NM_001182940.3_BG1 cds-NP_014297.3_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:434468-438874:+ gene-YNL102W_Bruggeman rna-NM_001182940.3_Bruggeman cds-NP_014297.3_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:477505-481911:+ gene-YNL102W_CAT1 rna-NM_001182940.3_CAT1 cds-NP_014297.3_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:424360-428766:+ gene-YNL102W_CBS1585 rna-NM_001182940.3_CBS1585 cds-NP_014297.3_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:492770-497176:+ gene-YNL102W_CBS436 rna-NM_001182940.3_CBS436 cds-NP_014297.3_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:419520-423926:+ gene-YNL102W_CBS6412 rna-NM_001182940.3_CBS6412 cds-NP_014297.3_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:420836-425242:+ gene-YNL102W_CBS6413 rna-NM_001182940.3_CBS6413 cds-NP_014297.3_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:423937-428343:+ gene-YNL102W_CENPK1137D rna-NM_001182940.3_CENPK1137D cds-NP_014297.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:420760-425166:+ gene-YNL102W_EthanolRed rna-NM_001182940.3_EthanolRed cds-NP_014297.3_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:416658-421064:+ gene-YNL102W_FaliES1 rna-NM_001182940.3_FaliES1 cds-NP_014297.3_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000140.1:4286-8692:+ gene-YNL102W_JAY291 rna-NM_001182940.3_JAY291 cds-NP_014297.3_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:430642-435048:+ gene-YNL102W_MUCL30387 rna-NM_001182940.3_MUCL30387 cds-NP_014297.3_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:466024-470430:+ gene-YNL102W_MUCL30388 rna-NM_001182940.3_MUCL30388 cds-NP_014297.3_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:421761-426167:+ gene-YNL102W_MUCL39482 rna-NM_001182940.3_MUCL39482 cds-NP_014297.3_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:425767-430173:+ gene-YNL102W_MUCL42920 rna-NM_001182940.3_MUCL42920 cds-NP_014297.3_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:430056-434462:+ gene-YNL102W_NCIM3186 rna-NM_001182940.3_NCIM3186 cds-NP_014297.3_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:423879-428285:+ gene-YNL102W_NCYC1407 rna-NM_001182940.3_NCYC1407 cds-NP_014297.3_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:422797-427203:+ gene-YNL102W_PE2H3 rna-NM_001182940.3_PE2H3 cds-NP_014297.3_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:422203-426609:+ gene-YNL102W_PE2H4 rna-NM_001182940.3_PE2H4 cds-NP_014297.3_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:430087-434493:+ gene-YNL102W_S288C rna-NM_001182940.3_S288C cds-NP_014297.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:15048-19454:+ gene-YNL102W_SA1 rna-NM_001182940.3_SA1 cds-NP_014297.3_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:417532-421938:+ gene-YNL102W_ThermosaccDry rna-NM_001182940.3_ThermosaccDry cds-NP_014297.3_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:436229-440635:+ gene-YNL102W_VR1 rna-NM_001182940.3_VR1 cds-NP_014297.3_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:327339-331745:+ gene-YNL102W_ZTW1 rna-NM_001182940.3_ZTW1 cds-NP_014297.3_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:428412-432815:+ gene-YNL102W_Sparadoxus rna-NM_001182940.3_Sparadoxus cds-NP_014297.3_Sparadoxus 90.9 99.7 Verified 1 1 1 False True False False False

Additional files