POF1 (YCL047C)


Gene profile

Gene name: POF1
Reference locus (S288C): YCL047C
Gene biotype: protein_coding

Description: Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT); catalyzes the conversion of nicotinamide mononucleotide (NMN) to nicotinamide adenine dinucleotide (NAD+); role in the nicotinamide riboside (NR) salvage pathway of NAD+ biosynthesis; involved in NR and NAD+ homeostasis; ATPase involved in protein quality control and filamentation pathways; interacts physically with Kss1p and suppresses the filamentation defect of a kss1 deletion

Top 10 interactors (score): NMA2 (0.92); ISN1 (0.9); NPT1 (0.9); NRK1 (0.9); BNA6 (0.9); SDT1 (0.9); UTR1 (0.9); QNS1 (0.9); NMA1 (0.886); NPY1 (0.8); SSM4 (0.704); KAR2 (0.695); YDR132C (0.69); YGL242C (0.69); YDL109C (0.674); YCR101C (0.671); MPO1 (0.671); DSD1 (0.652); HST1 (0.65); SIR2 (0.65)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:44943-45719:- gene-YCL047C_AKU4011 rna-NM_001178692.1_AKU4011 cds-NP_009883.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000086.1:102-878:+ gene-YCL047C_BG1 rna-NM_001178692.1_BG1 cds-NP_009883.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:32806-33582:- gene-YCL047C_Bruggeman rna-NM_001178692.1_Bruggeman cds-NP_009883.1_Bruggeman 99.4 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:44827-45603:- gene-YCL047C_CAT1 rna-NM_001178692.1_CAT1 cds-NP_009883.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:45639-46415:- gene-YCL047C_CBS1585 rna-NM_001178692.1_CBS1585 cds-NP_009883.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:44171-44947:- gene-YCL047C_CBS436 rna-NM_001178692.1_CBS436 cds-NP_009883.1_CBS436 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:33441-34217:- gene-YCL047C_CBS6412 rna-NM_001178692.1_CBS6412 cds-NP_009883.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:44466-45242:- gene-YCL047C_CBS6413 rna-NM_001178692.1_CBS6413 cds-NP_009883.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:43231-44007:- gene-YCL047C_CENPK1137D rna-NM_001178692.1_CENPK1137D cds-NP_009883.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:43200-43976:- gene-YCL047C_EthanolRed rna-NM_001178692.1_EthanolRed cds-NP_009883.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:43965-44741:- gene-YCL047C_FaliES1 rna-NM_001178692.1_FaliES1 cds-NP_009883.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000225.1:39602-40378:+ gene-YCL047C_JAY291 rna-NM_001178692.1_JAY291 cds-NP_009883.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:31409-32185:- gene-YCL047C_MUCL30387 rna-NM_001178692.1_MUCL30387 cds-NP_009883.1_MUCL30387 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:31685-32461:- gene-YCL047C_MUCL30388 rna-NM_001178692.1_MUCL30388 cds-NP_009883.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:46028-46804:- gene-YCL047C_MUCL39482 rna-NM_001178692.1_MUCL39482 cds-NP_009883.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:32199-32975:- gene-YCL047C_MUCL42920 rna-NM_001178692.1_MUCL42920 cds-NP_009883.1_MUCL42920 99.4 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:43293-44069:- gene-YCL047C_NCIM3186 rna-NM_001178692.1_NCIM3186 cds-NP_009883.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:46362-47138:- gene-YCL047C_NCYC1407 rna-NM_001178692.1_NCYC1407 cds-NP_009883.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:44128-44904:- gene-YCL047C_PE2H3 rna-NM_001178692.1_PE2H3 cds-NP_009883.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:44085-44861:- gene-YCL047C_PE2H4 rna-NM_001178692.1_PE2H4 cds-NP_009883.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:43661-44437:- gene-YCL047C_S288C rna-NM_001178692.1_S288C cds-NP_009883.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000061.1:30808-31584:- gene-YCL047C_SA1 rna-NM_001178692.1_SA1 cds-NP_009883.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:44282-45058:- gene-YCL047C_ThermosaccDry rna-NM_001178692.1_ThermosaccDry cds-NP_009883.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:50599-51375:- gene-YCL047C_VR1 rna-NM_001178692.1_VR1 cds-NP_009883.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:44493-45269:- gene-YCL047C_ZTW1 rna-NM_001178692.1_ZTW1 cds-NP_009883.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:74124-74900:- gene-YCL047C_Sparadoxus rna-NM_001178692.1_Sparadoxus cds-NP_009883.1_Sparadoxus 89.2 99.8 Verified 1 1 1 False True False False False

Additional files