POB3 (YML069W)


Gene profile

Gene name: POB3
Reference locus (S288C): YML069W
Gene biotype: protein_coding

Description: Subunit of the heterodimeric FACT complex (Spt16p-Pob3p); FACT associates with chromatin via interaction with Nhp6Ap and Nhp6Bp, and reorganizes nucleosomes to facilitate access to DNA by RNA and DNA polymerases; protein abundance increases in response to DNA replication stress; Belongs to the SSRP1 family

Top 10 interactors (score): RTF1 (0.999); MCM2 (0.999); CKB2 (0.999); SPT16 (0.999); HHF1 (0.999); CHD1 (0.999); LEO1 (0.999); SPT6 (0.999); HTA1 (0.998); MCM4 (0.998); HHF2 (0.998); HHT1 (0.997); CKB1 (0.997); HHT2 (0.997); HTA2 (0.996); MCM7 (0.996); HTB1 (0.995); PAF1 (0.995); MCM5 (0.995); CTR9 (0.994)

Homologues (species, bitscore): SSRP1 (Homo sapiens, 292.4); Ssrp1 (Mus musculus, 290.8); ssrp1a (Danio rerio, 309.7); ssrp1 (Xenopus tropicalis, 270.4); Ssrp (Drosophila melanogaster, 254.2); hmg-4 (Caenorhabditis elegans, 236.9); HMG (Arabidopsis thaliana, 255.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:129235-130893:+ gene-YML069W_AKU4011 rna-NM_001182428.1_AKU4011 cds-NP_013642.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:345246-346904:- gene-YML069W_BG1 rna-NM_001182428.1_BG1 cds-NP_013642.1_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:135377-137035:+ gene-YML069W_Bruggeman rna-NM_001182428.1_Bruggeman cds-NP_013642.1_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:137051-138709:+ gene-YML069W_CAT1 rna-NM_001182428.1_CAT1 cds-NP_013642.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:129244-130902:+ gene-YML069W_CBS1585 rna-NM_001182428.1_CBS1585 cds-NP_013642.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:135145-136803:+ gene-YML069W_CBS436 rna-NM_001182428.1_CBS436 cds-NP_013642.1_CBS436 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:129952-131610:+ gene-YML069W_CBS6412 rna-NM_001182428.1_CBS6412 cds-NP_013642.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:128427-130085:+ gene-YML069W_CBS6413 rna-NM_001182428.1_CBS6413 cds-NP_013642.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:130223-131881:+ gene-YML069W_CENPK1137D rna-NM_001182428.1_CENPK1137D cds-NP_013642.1_CENPK1137D 99.6 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:129508-131166:+ gene-YML069W_EthanolRed rna-NM_001182428.1_EthanolRed cds-NP_013642.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:130015-131673:+ gene-YML069W_FaliES1 rna-NM_001182428.1_FaliES1 cds-NP_013642.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000366.1:25435-27093:- gene-YML069W_JAY291 rna-NM_001182428.1_JAY291 cds-NP_013642.1_JAY291 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:133907-135565:+ gene-YML069W_MUCL30387 rna-NM_001182428.1_MUCL30387 cds-NP_013642.1_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:137082-138740:+ gene-YML069W_MUCL30388 rna-NM_001182428.1_MUCL30388 cds-NP_013642.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:129255-130913:+ gene-YML069W_MUCL39482 rna-NM_001182428.1_MUCL39482 cds-NP_013642.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:135088-136746:+ gene-YML069W_MUCL42920 rna-NM_001182428.1_MUCL42920 cds-NP_013642.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:135454-137112:+ gene-YML069W_NCIM3186 rna-NM_001182428.1_NCIM3186 cds-NP_013642.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:130050-131708:+ gene-YML069W_NCYC1407 rna-NM_001182428.1_NCYC1407 cds-NP_013642.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:135459-137117:+ gene-YML069W_PE2H3 rna-NM_001182428.1_PE2H3 cds-NP_013642.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:135323-136981:+ gene-YML069W_PE2H4 rna-NM_001182428.1_PE2H4 cds-NP_013642.1_PE2H4 99.6 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:135500-137158:+ gene-YML069W_S288C rna-NM_001182428.1_S288C cds-NP_013642.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000041.1:47103-48761:- gene-YML069W_SA1 rna-NM_001182428.1_SA1 cds-NP_013642.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:129307-130965:+ gene-YML069W_ThermosaccDry rna-NM_001182428.1_ThermosaccDry cds-NP_013642.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:133671-135329:+ gene-YML069W_VR1 rna-NM_001182428.1_VR1 cds-NP_013642.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:108844-110502:+ gene-YML069W_ZTW1 rna-NM_001182428.1_ZTW1 cds-NP_013642.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:140416-142074:+ gene-YML069W_Sparadoxus rna-NM_001182428.1_Sparadoxus cds-NP_013642.1_Sparadoxus 92.9 100.0 Verified 1 1 1 False True False False False

Additional files