PMT4 (YJR143C)


Gene profile

Gene name: PMT4
Reference locus (S288C): YJR143C
Gene biotype: protein_coding

Description: Dolichyl-phosphate-mannose--protein mannosyltransferase 4; Protein O-mannosyltransferase; transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; appears to form homodimers in vivo and does not complex with other Pmt proteins; target for new antifungals; Belongs to the glycosyltransferase 39 family

Top 10 interactors (score): KRE2 (0.974); PMT1 (0.972); KTR1 (0.958); PMT2 (0.957); KTR3 (0.915); PMT3 (0.905); OAC1 (0.899); VAN1 (0.887); PMT5 (0.872); MNN11 (0.868); GPI14 (0.853); MSB2 (0.825); PSA1 (0.824); GAS1 (0.811); MNN10 (0.805); GPI18 (0.788); HOC1 (0.782); ALG7 (0.778); MNN9 (0.771); PMT6 (0.753)

Homologues (species, bitscore): POMT2 (Homo sapiens, 325.5); Pomt2 (Mus musculus, 332.8); pomt2 (Danio rerio, 338.6); POMT2 (Xenopus tropicalis, 342.4); rt (Drosophila melanogaster, 326.6); R12E2.13 (Caenorhabditis elegans, 50.8); SDF2 (Arabidopsis thaliana, 50.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:669823-672111:- gene-YJR143C_AKU4011 rna-NM_001181801.1_AKU4011 cds-NP_012677.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000076.1:1490-3778:+ gene-YJR143C_BG1 rna-NM_001181801.1_BG1 cds-NP_012677.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:685556-687844:- gene-YJR143C_Bruggeman rna-NM_001181801.1_Bruggeman cds-NP_012677.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:690191-692479:- gene-YJR143C_CAT1 rna-NM_001181801.1_CAT1 cds-NP_012677.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:681867-684155:- gene-YJR143C_CBS1585 rna-NM_001181801.1_CBS1585 cds-NP_012677.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:700737-703025:- gene-YJR143C_CBS436 rna-NM_001181801.1_CBS436 cds-NP_012677.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:668642-670930:- gene-YJR143C_CBS6412 rna-NM_001181801.1_CBS6412 cds-NP_012677.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:671301-673589:- gene-YJR143C_CBS6413 rna-NM_001181801.1_CBS6413 cds-NP_012677.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:680685-682973:- gene-YJR143C_CENPK1137D rna-NM_001181801.1_CENPK1137D cds-NP_012677.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:674245-676533:- gene-YJR143C_EthanolRed rna-NM_001181801.1_EthanolRed cds-NP_012677.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:685708-687996:- gene-YJR143C_FaliES1 rna-NM_001181801.1_FaliES1 cds-NP_012677.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000054.1:1162-3450:+ gene-YJR143C_JAY291 rna-NM_001181801.1_JAY291 cds-NP_012677.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:684582-686870:- gene-YJR143C_MUCL30387 rna-NM_001181801.1_MUCL30387 cds-NP_012677.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:682069-684357:- gene-YJR143C_MUCL30388 rna-NM_001181801.1_MUCL30388 cds-NP_012677.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:675352-677640:- gene-YJR143C_MUCL39482 rna-NM_001181801.1_MUCL39482 cds-NP_012677.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:680087-682375:- gene-YJR143C_MUCL42920 rna-NM_001181801.1_MUCL42920 cds-NP_012677.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:698305-700593:- gene-YJR143C_NCIM3186 rna-NM_001181801.1_NCIM3186 cds-NP_012677.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:672899-675187:- gene-YJR143C_NCYC1407 rna-NM_001181801.1_NCYC1407 cds-NP_012677.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:691090-693378:- gene-YJR143C_PE2H3 rna-NM_001181801.1_PE2H3 cds-NP_012677.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:684779-687067:- gene-YJR143C_PE2H4 rna-NM_001181801.1_PE2H4 cds-NP_012677.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:698326-700614:- gene-YJR143C_S288C rna-NM_001181801.1_S288C cds-NP_012677.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000069.1:1515-3803:+ gene-YJR143C_SA1 rna-NM_001181801.1_SA1 cds-NP_012677.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:679639-681927:- gene-YJR143C_ThermosaccDry rna-NM_001181801.1_ThermosaccDry cds-NP_012677.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:682010-684298:- gene-YJR143C_VR1 rna-NM_001181801.1_VR1 cds-NP_012677.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:658987-661275:- gene-YJR143C_ZTW1 rna-NM_001181801.1_ZTW1 cds-NP_012677.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:693283-695571:- gene-YJR143C_Sparadoxus rna-NM_001181801.1_Sparadoxus cds-NP_012677.1_Sparadoxus 91.9 99.9 Verified 1 1 1 False True False False False

Additional files