Gene name: PMT3
Reference locus (S288C): YOR321W
Gene biotype: protein_coding
Description: Dolichyl-phosphate-mannose--protein mannosyltransferase 3; Protein O-mannosyltransferase; transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt5p, can instead interact with Pmt1p in some conditions; antifungal drug target; PMT3 has a paralog, PMT2, that arose from the whole genome duplication
Top 10 interactors (score): PMT1 (0.987); PMT5 (0.986); PMT2 (0.98); KTR1 (0.95); MNN10 (0.929); HOC1 (0.911); PMT4 (0.905); KTR3 (0.903); KRE2 (0.903); MNN11 (0.81); MNN9 (0.794); WBP1 (0.788); ALG12 (0.769); GPI18 (0.761); GPI14 (0.757); VAN1 (0.746); PBN1 (0.746); ANP1 (0.722); PGA1 (0.72); SEC59 (0.707)
Homologues (species, bitscore): POMT2 (Homo sapiens, 416.0); Pomt2 (Mus musculus, 422.5); pomt2 (Danio rerio, 437.6); POMT2 (Xenopus tropicalis, 433.0); tw (Drosophila melanogaster, 403.3); R12E2.13 (Caenorhabditis elegans, 74.3); SDF2 (Arabidopsis thaliana, 59.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:906521-908782:+ | gene-YOR321W_AKU4011 | rna-NM_001183741.1_AKU4011 | cds-NP_014966.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:308525-310786:+ | gene-YOR321W_BG1 | rna-NM_001183741.1_BG1 | cds-NP_014966.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:891930-894191:+ | gene-YOR321W_Bruggeman | rna-NM_001183741.1_Bruggeman | cds-NP_014966.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:892641-894902:+ | gene-YOR321W_CAT1 | rna-NM_001183741.1_CAT1 | cds-NP_014966.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:890341-892602:+ | gene-YOR321W_CBS1585 | rna-NM_001183741.1_CBS1585 | cds-NP_014966.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:888165-890426:+ | gene-YOR321W_CBS436 | rna-NM_001183741.1_CBS436 | cds-NP_014966.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:886051-888312:+ | gene-YOR321W_CBS6412 | rna-NM_001183741.1_CBS6412 | cds-NP_014966.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:895179-897440:+ | gene-YOR321W_CBS6413 | rna-NM_001183741.1_CBS6413 | cds-NP_014966.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:915806-918067:+ | gene-YOR321W_CENPK1137D | rna-NM_001183741.1_CENPK1137D | cds-NP_014966.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:882435-884696:+ | gene-YOR321W_EthanolRed | rna-NM_001183741.1_EthanolRed | cds-NP_014966.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:888058-890319:+ | gene-YOR321W_FaliES1 | rna-NM_001183741.1_FaliES1 | cds-NP_014966.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:112948-115209:- | gene-YOR321W_JAY291 | rna-NM_001183741.1_JAY291 | cds-NP_014966.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:896169-898430:+ | gene-YOR321W_MUCL30387 | rna-NM_001183741.1_MUCL30387 | cds-NP_014966.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:904182-906443:+ | gene-YOR321W_MUCL30388 | rna-NM_001183741.1_MUCL30388 | cds-NP_014966.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:896886-899147:+ | gene-YOR321W_MUCL39482 | rna-NM_001183741.1_MUCL39482 | cds-NP_014966.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:906351-908612:+ | gene-YOR321W_MUCL42920 | rna-NM_001183741.1_MUCL42920 | cds-NP_014966.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:915919-918180:+ | gene-YOR321W_NCIM3186 | rna-NM_001183741.1_NCIM3186 | cds-NP_014966.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:897887-900148:+ | gene-YOR321W_NCYC1407 | rna-NM_001183741.1_NCYC1407 | cds-NP_014966.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:896106-898367:+ | gene-YOR321W_PE2H3 | rna-NM_001183741.1_PE2H3 | cds-NP_014966.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:912458-914719:+ | gene-YOR321W_PE2H4 | rna-NM_001183741.1_PE2H4 | cds-NP_014966.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:916030-918291:+ | gene-YOR321W_S288C | rna-NM_001183741.1_S288C | cds-NP_014966.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000016.1:26357-28618:+ | gene-YOR321W_SA1 | rna-NM_001183741.1_SA1 | cds-NP_014966.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:887241-889502:+ | gene-YOR321W_ThermosaccDry | rna-NM_001183741.1_ThermosaccDry | cds-NP_014966.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:950526-952787:+ | gene-YOR321W_VR1 | rna-NM_001183741.1_VR1 | cds-NP_014966.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:620114-622375:+ | gene-YOR321W_ZTW1 | rna-NM_001183741.1_ZTW1 | cds-NP_014966.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:894453-896714:+ | gene-YOR321W_Sparadoxus | rna-NM_001183741.1_Sparadoxus | cds-NP_014966.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |