Gene name: PMT2
Reference locus (S288C): YAL023C
Gene biotype: protein_coding
Description: Dolichyl-phosphate-mannose--protein mannosyltransferase 2; Protein O-mannosyltransferase of the ER membrane; transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; involved in ER quality control; acts in a complex with Pmt1p, can instead interact with Pmt5p; antifungal drug target; PMT2 has a paralog, PMT3, that arose from the whole genome duplication; Belongs to the glycosyltransferase 39 family
Top 10 interactors (score): PMT1 (0.999); PMT5 (0.984); PMT3 (0.98); KRE2 (0.974); PMT4 (0.957); MNN10 (0.95); KTR1 (0.933); HOC1 (0.928); ANP1 (0.921); KTR3 (0.906); VAN1 (0.904); CWH41 (0.902); ALG6 (0.881); ROT2 (0.867); OST3 (0.861); MNS1 (0.855); MNN9 (0.854); GAS1 (0.835); SLG1 (0.83); MNN11 (0.817)
Homologues (species, bitscore): POMT2 (Homo sapiens, 451.1); Pomt2 (Mus musculus, 448.0); pomt2 (Danio rerio, 451.4); POMT2 (Xenopus tropicalis, 443.7); tw (Drosophila melanogaster, 401.4); R12E2.13 (Caenorhabditis elegans, 73.6); SDF2 (Arabidopsis thaliana, 62.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:91397-93676:- | gene-YAL023C_AKU4011 | rna-NM_001178168.1_AKU4011 | cds-NP_009379.2_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000070.1:78342-80621:- | gene-YAL023C_BG1 | rna-NM_001178168.1_BG1 | cds-NP_009379.2_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:106269-108548:- | gene-YAL023C_Bruggeman | rna-NM_001178168.1_Bruggeman | cds-NP_009379.2_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:92602-94881:- | gene-YAL023C_CAT1 | rna-NM_001178168.1_CAT1 | cds-NP_009379.2_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:104416-106695:- | gene-YAL023C_CBS1585 | rna-NM_001178168.1_CBS1585 | cds-NP_009379.2_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:104664-106943:- | gene-YAL023C_CBS436 | rna-NM_001178168.1_CBS436 | cds-NP_009379.2_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:717512-719791:- | gene-YAL023C_CBS6412 | rna-NM_001178168.1_CBS6412 | cds-NP_009379.2_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:102679-104958:- | gene-YAL023C_CBS6413 | rna-NM_001178168.1_CBS6413 | cds-NP_009379.2_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:106396-108675:- | gene-YAL023C_CENPK1137D | rna-NM_001178168.1_CENPK1137D | cds-NP_009379.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:92820-95099:- | gene-YAL023C_EthanolRed | rna-NM_001178168.1_EthanolRed | cds-NP_009379.2_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:107444-109723:- | gene-YAL023C_FaliES1 | rna-NM_001178168.1_FaliES1 | cds-NP_009379.2_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000084.1:78716-80995:- | gene-YAL023C_JAY291 | rna-NM_001178168.1_JAY291 | cds-NP_009379.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:107383-109662:- | gene-YAL023C_MUCL30387 | rna-NM_001178168.1_MUCL30387 | cds-NP_009379.2_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:103918-106197:- | gene-YAL023C_MUCL30388 | rna-NM_001178168.1_MUCL30388 | cds-NP_009379.2_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:103198-105477:- | gene-YAL023C_MUCL39482 | rna-NM_001178168.1_MUCL39482 | cds-NP_009379.2_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:105580-107859:- | gene-YAL023C_MUCL42920 | rna-NM_001178168.1_MUCL42920 | cds-NP_009379.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:106149-108428:- | gene-YAL023C_NCIM3186 | rna-NM_001178168.1_NCIM3186 | cds-NP_009379.2_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:91087-93366:- | gene-YAL023C_NCYC1407 | rna-NM_001178168.1_NCYC1407 | cds-NP_009379.2_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:92990-95269:- | gene-YAL023C_PE2H3 | rna-NM_001178168.1_PE2H3 | cds-NP_009379.2_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:92709-94988:- | gene-YAL023C_PE2H4 | rna-NM_001178168.1_PE2H4 | cds-NP_009379.2_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:106272-108551:- | gene-YAL023C_S288C | rna-NM_001178168.1_S288C | cds-NP_009379.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000077.1:23140-25419:- | gene-YAL023C_SA1 | rna-NM_001178168.1_SA1 | cds-NP_009379.2_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:106957-109236:- | gene-YAL023C_ThermosaccDry | rna-NM_001178168.1_ThermosaccDry | cds-NP_009379.2_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:108243-110522:- | gene-YAL023C_VR1 | rna-NM_001178168.1_VR1 | cds-NP_009379.2_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:78768-81047:- | gene-YAL023C_ZTW1 | rna-NM_001178168.1_ZTW1 | cds-NP_009379.2_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:96351-98630:- | gene-YAL023C_Sparadoxus | rna-NM_001178168.1_Sparadoxus | cds-NP_009379.2_Sparadoxus | 93.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |