PMS1 (YNL082W)


Gene profile

Gene name: PMS1
Reference locus (S288C): YNL082W
Gene biotype: protein_coding

Description: ATP-binding protein required for mismatch repair; required for both mitosis and meiosis; functions as a heterodimer with Mlh1p; binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL

Top 10 interactors (score): MLH1 (0.999); MSH3 (0.999); MSH6 (0.999); MSH2 (0.999); EXO1 (0.996); POL3 (0.977); RAD10 (0.965); RAD14 (0.963); POL2 (0.951); MSH5 (0.943); MSH4 (0.94); POL30 (0.94); RAD2 (0.936); MLH3 (0.906); MSH1 (0.892); RAD1 (0.89); RAD3 (0.858); CDC9 (0.849); RAD27 (0.845); RAD51 (0.843)

Homologues (species, bitscore): PMS2 (Homo sapiens, 459.9); Pms2 (Mus musculus, 465.7); pms2 (Danio rerio, 461.1); pms2 (Xenopus tropicalis, 468.8); Pms2 (Drosophila melanogaster, 442.6); pms-2 (Caenorhabditis elegans, 413.3); PMS1 (Arabidopsis thaliana, 418.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:467036-469669:+ gene-YNL082W_AKU4011 rna-NM_001182920.3_AKU4011 cds-NP_014317.4_AKU4011 98.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:371121-373742:+ gene-YNL082W_BG1 rna-NM_001182920.3_BG1 cds-NP_014317.4_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:477757-480390:+ gene-YNL082W_Bruggeman rna-NM_001182920.3_Bruggeman cds-NP_014317.4_Bruggeman 98.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:520782-523403:+ gene-YNL082W_CAT1 rna-NM_001182920.3_CAT1 cds-NP_014317.4_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:467706-470339:+ gene-YNL082W_CBS1585 rna-NM_001182920.3_CBS1585 cds-NP_014317.4_CBS1585 98.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:536097-538718:+ gene-YNL082W_CBS436 rna-NM_001182920.3_CBS436 cds-NP_014317.4_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:462802-465435:+ gene-YNL082W_CBS6412 rna-NM_001182920.3_CBS6412 cds-NP_014317.4_CBS6412 98.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:464118-466751:+ gene-YNL082W_CBS6413 rna-NM_001182920.3_CBS6413 cds-NP_014317.4_CBS6413 98.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:467214-469835:+ gene-YNL082W_CENPK1137D rna-NM_001182920.3_CENPK1137D cds-NP_014317.4_CENPK1137D 99.9 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:469862-472495:+ gene-YNL082W_EthanolRed rna-NM_001182920.3_EthanolRed cds-NP_014317.4_EthanolRed 98.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:460391-463024:+ gene-YNL082W_FaliES1 rna-NM_001182920.3_FaliES1 cds-NP_014317.4_FaliES1 98.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000317.1:10574-13207:- gene-YNL082W_JAY291 rna-NM_001182920.3_JAY291 cds-NP_014317.4_JAY291 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:473934-476567:+ gene-YNL082W_MUCL30387 rna-NM_001182920.3_MUCL30387 cds-NP_014317.4_MUCL30387 98.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:509306-511939:+ gene-YNL082W_MUCL30388 rna-NM_001182920.3_MUCL30388 cds-NP_014317.4_MUCL30388 98.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:465110-467743:+ gene-YNL082W_MUCL39482 rna-NM_001182920.3_MUCL39482 cds-NP_014317.4_MUCL39482 98.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:469049-471670:+ gene-YNL082W_MUCL42920 rna-NM_001182920.3_MUCL42920 cds-NP_014317.4_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:473360-475981:+ gene-YNL082W_NCIM3186 rna-NM_001182920.3_NCIM3186 cds-NP_014317.4_NCIM3186 98.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:467158-469791:+ gene-YNL082W_NCYC1407 rna-NM_001182920.3_NCYC1407 cds-NP_014317.4_NCYC1407 98.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:470397-473030:+ gene-YNL082W_PE2H3 rna-NM_001182920.3_PE2H3 cds-NP_014317.4_PE2H3 98.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:465472-468105:+ gene-YNL082W_PE2H4 rna-NM_001182920.3_PE2H4 cds-NP_014317.4_PE2H4 98.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:473391-476012:+ gene-YNL082W_S288C rna-NM_001182920.3_S288C cds-NP_014317.4_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:58334-60967:+ gene-YNL082W_SA1 rna-NM_001182920.3_SA1 cds-NP_014317.4_SA1 99.0 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:461266-463899:+ gene-YNL082W_ThermosaccDry rna-NM_001182920.3_ThermosaccDry cds-NP_014317.4_ThermosaccDry 98.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:480379-483012:+ gene-YNL082W_VR1 rna-NM_001182920.3_VR1 cds-NP_014317.4_VR1 98.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:370615-373248:+ gene-YNL082W_ZTW1 rna-NM_001182920.3_ZTW1 cds-NP_014317.4_ZTW1 98.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:476766-479408:+ gene-YNL082W_Sparadoxus rna-NM_001182920.3_Sparadoxus cds-NP_014317.4_Sparadoxus 86.4 99.6 Verified 1 1 1 False True False False False

Additional files