Gene name: PMR1
Reference locus (S288C): YGL167C
Gene biotype: protein_coding
Description: Calcium-transporting ATPase 1; High affinity Ca2+/Mn2+ P-type ATPase; required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting, processing; D53A mutant (Mn2+ transporting) is rapamycin sensitive, Q783A mutant (Ca2+ transporting) is rapamycin resistant; Mn2+ transport into Golgi lumen required for rapamycin sensitivity; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease; human ATP2C1 can complement yeast null mutant; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family
Top 10 interactors (score): PMC1 (0.999); VCX1 (0.976); GDT1 (0.967); CRZ1 (0.958); HUR1 (0.936); CCH1 (0.932); CCC1 (0.914); CMD1 (0.903); SMF1 (0.866); SEC4 (0.863); SMF2 (0.845); SOD1 (0.828); BSD2 (0.82); YVC1 (0.815); NYV1 (0.791); CNB1 (0.787); SPF1 (0.786); MID1 (0.785); RCN1 (0.781); CMK2 (0.77)
Homologues (species, bitscore): ATP2C1 (Homo sapiens, 867.1); Atp2c1 (Mus musculus, 866.3); atp2c1 (Danio rerio, 858.2); atp2c1 (Xenopus tropicalis, 845.9); SPoCk (Drosophila melanogaster, 826.2); pmr-1 (Caenorhabditis elegans, 830.9); ECA1 (Arabidopsis thaliana, 492.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:190188-193040:- | gene-YGL167C_AKU4011 | rna-NM_001181032.1_AKU4011 | cds-NP_011348.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:217322-220174:+ | gene-YGL167C_BG1 | rna-NM_001181032.1_BG1 | cds-NP_011348.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:192349-195201:- | gene-YGL167C_Bruggeman | rna-NM_001181032.1_Bruggeman | cds-NP_011348.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:188219-191071:- | gene-YGL167C_CAT1 | rna-NM_001181032.1_CAT1 | cds-NP_011348.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:193327-196179:- | gene-YGL167C_CBS1585 | rna-NM_001181032.1_CBS1585 | cds-NP_011348.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:188209-191061:- | gene-YGL167C_CBS436 | rna-NM_001181032.1_CBS436 | cds-NP_011348.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:179790-182642:- | gene-YGL167C_CBS6412 | rna-NM_001181032.1_CBS6412 | cds-NP_011348.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:187639-190491:- | gene-YGL167C_CBS6413 | rna-NM_001181032.1_CBS6413 | cds-NP_011348.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:187843-190695:- | gene-YGL167C_CENPK1137D | rna-NM_001181032.1_CENPK1137D | cds-NP_011348.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:179995-182847:- | gene-YGL167C_EthanolRed | rna-NM_001181032.1_EthanolRed | cds-NP_011348.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:181241-184093:- | gene-YGL167C_FaliES1 | rna-NM_001181032.1_FaliES1 | cds-NP_011348.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000090.1:31439-34291:- | gene-YGL167C_JAY291 | rna-NM_001181032.1_JAY291 | cds-NP_011348.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:189597-192449:- | gene-YGL167C_MUCL30387 | rna-NM_001181032.1_MUCL30387 | cds-NP_011348.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:192687-195539:- | gene-YGL167C_MUCL30388 | rna-NM_001181032.1_MUCL30388 | cds-NP_011348.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:190351-193203:- | gene-YGL167C_MUCL39482 | rna-NM_001181032.1_MUCL39482 | cds-NP_011348.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:192937-195789:- | gene-YGL167C_MUCL42920 | rna-NM_001181032.1_MUCL42920 | cds-NP_011348.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:187616-190468:- | gene-YGL167C_NCIM3186 | rna-NM_001181032.1_NCIM3186 | cds-NP_011348.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:181815-184667:- | gene-YGL167C_NCYC1407 | rna-NM_001181032.1_NCYC1407 | cds-NP_011348.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:183740-186592:- | gene-YGL167C_PE2H3 | rna-NM_001181032.1_PE2H3 | cds-NP_011348.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:183291-186143:- | gene-YGL167C_PE2H4 | rna-NM_001181032.1_PE2H4 | cds-NP_011348.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:187616-190468:- | gene-YGL167C_S288C | rna-NM_001181032.1_S288C | cds-NP_011348.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000067.1:47401-50253:- | gene-YGL167C_SA1 | rna-NM_001181032.1_SA1 | cds-NP_011348.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:181470-184322:- | gene-YGL167C_ThermosaccDry | rna-NM_001181032.1_ThermosaccDry | cds-NP_011348.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:188645-191497:- | gene-YGL167C_VR1 | rna-NM_001181032.1_VR1 | cds-NP_011348.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:179921-182773:- | gene-YGL167C_ZTW1 | rna-NM_001181032.1_ZTW1 | cds-NP_011348.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:186793-189645:- | gene-YGL167C_Sparadoxus | rna-NM_001181032.1_Sparadoxus | cds-NP_011348.1_Sparadoxus | 91.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |