Gene name: PMA1
Reference locus (S288C): YGL008C
Gene biotype: protein_coding
Description: Plasma membrane P2-type H+-ATPase; pumps protons out of cell; major regulator of cytoplasmic pH and plasma membrane potential; long-lived protein asymmetrically distributed at plasma membrane between mother cells and buds; accumulates at high levels in mother cells during aging, buds emerge with very low levels of Pma1p, newborn cells have low levels of Pma1p; Hsp30p plays a role in Pma1p regulation; interactions with Std1p appear to propagate [GAR+]
Top 10 interactors (score): YEF3 (0.959); GAS1 (0.927); GAP1 (0.925); CDC19 (0.923); IPP1 (0.911); PGK1 (0.909); PPA2 (0.904); PTK2 (0.881); TRK1 (0.879); VPH1 (0.873); ADH1 (0.864); PMP1 (0.856); DPM1 (0.85); ACT1 (0.847); TRK2 (0.843); STD1 (0.84); PMA2 (0.833); PDR5 (0.822); CAN1 (0.806); PIL1 (0.803)
Homologues (species, bitscore): ATP2C2 (Homo sapiens, 230.3); Atp2c2 (Mus musculus, 226.9); atp1a1a.5 (Danio rerio, 234.6); Atp12a (Xenopus tropicalis, 238.8); Ca-P60A (Drosophila melanogaster, 227.6); pmr-1 (Caenorhabditis elegans, 263.8); HA7 (Arabidopsis thaliana, 506.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:481963-484719:- | gene-YGL008C_AKU4011 | rna-NM_001180873.1_AKU4011 | cds-NP_011507.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:91393-94149:+ | gene-YGL008C_BG1 | rna-NM_001180873.1_BG1 | cds-NP_011507.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:482932-485688:- | gene-YGL008C_Bruggeman | rna-NM_001180873.1_Bruggeman | cds-NP_011507.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:481226-484231:- | gene-YGL008C_CAT1 | rna-NM_001180873.1_CAT1 | cds-NP_011507.1_CAT1 | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:483436-486192:- | gene-YGL008C_CBS1585 | rna-NM_001180873.1_CBS1585 | cds-NP_011507.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:477812-480568:- | gene-YGL008C_CBS436 | rna-NM_001180873.1_CBS436 | cds-NP_011507.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:476051-478807:- | gene-YGL008C_CBS6412 | rna-NM_001180873.1_CBS6412 | cds-NP_011507.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:480107-482863:- | gene-YGL008C_CBS6413 | rna-NM_001180873.1_CBS6413 | cds-NP_011507.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:479731-482487:- | gene-YGL008C_CENPK1137D | rna-NM_001180873.1_CENPK1137D | cds-NP_011507.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:470334-473090:- | gene-YGL008C_EthanolRed | rna-NM_001180873.1_EthanolRed | cds-NP_011507.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:473587-476343:- | gene-YGL008C_FaliES1 | rna-NM_001180873.1_FaliES1 | cds-NP_011507.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000020.1:12219-14975:- | gene-YGL008C_JAY291 | rna-NM_001180873.1_JAY291 | cds-NP_011507.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:480155-482911:- | gene-YGL008C_MUCL30387 | rna-NM_001180873.1_MUCL30387 | cds-NP_011507.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:482706-485462:- | gene-YGL008C_MUCL30388 | rna-NM_001180873.1_MUCL30388 | cds-NP_011507.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:479275-482031:- | gene-YGL008C_MUCL39482 | rna-NM_001180873.1_MUCL39482 | cds-NP_011507.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:488710-491466:- | gene-YGL008C_MUCL42920 | rna-NM_001180873.1_MUCL42920 | cds-NP_011507.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:479910-482666:- | gene-YGL008C_NCIM3186 | rna-NM_001180873.1_NCIM3186 | cds-NP_011507.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:473297-476053:- | gene-YGL008C_NCYC1407 | rna-NM_001180873.1_NCYC1407 | cds-NP_011507.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:475987-478743:- | gene-YGL008C_PE2H3 | rna-NM_001180873.1_PE2H3 | cds-NP_011507.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:481037-483793:- | gene-YGL008C_PE2H4 | rna-NM_001180873.1_PE2H4 | cds-NP_011507.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:479910-482666:- | gene-YGL008C_S288C | rna-NM_001180873.1_S288C | cds-NP_011507.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:72915-75671:+ | gene-YGL008C_SA1 | rna-NM_001180873.1_SA1 | cds-NP_011507.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:492912-495668:- | gene-YGL008C_ThermosaccDry | rna-NM_001180873.1_ThermosaccDry | cds-NP_011507.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:582994-585750:- | gene-YGL008C_VR1 | rna-NM_001180873.1_VR1 | cds-NP_011507.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:471515-474271:- | gene-YGL008C_ZTW1 | rna-NM_001180873.1_ZTW1 | cds-NP_011507.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:481046-483805:- | gene-YGL008C_Sparadoxus | rna-NM_001180873.1_Sparadoxus | cds-NP_011507.1_Sparadoxus | 96.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |