Gene name: PLB1
Reference locus (S288C): YMR008C
Gene biotype: protein_coding
Description: Phospholipase B (lysophospholipase) involved in lipid metabolism; required for efficient acyl chain remodeling of newly synthesized phosphatidylethanolamine-derived phosphatidylcholine; required for deacylation of phosphatidylcholine and phosphatidylethanolamine but not phosphatidylinositol; PLB1 has a paralog, PLB3, that arose from the whole genome duplication
Top 10 interactors (score): HOG1 (0.946); NTE1 (0.946); SLT2 (0.944); ALE1 (0.942); FUS3 (0.938); SMK1 (0.938); TGL5 (0.937); TGL4 (0.93); GDE1 (0.926); PLB2 (0.883); LAC1 (0.844); PLB3 (0.805); URA5 (0.774); SOD1 (0.752); CDA2 (0.717); SEC14 (0.696); GIT1 (0.654); CDA1 (0.62); GPC1 (0.577); BGL2 (0.57)
Homologues (species, bitscore): PLA2G4F (Homo sapiens, 68.9); Pla2g4a (Mus musculus, 67.8); LOC798864 (Danio rerio, 85.1); pla2g4d (Xenopus tropicalis, 58.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:330206-332200:- | gene-YMR008C_AKU4011 | rna-NM_001182504.1_AKU4011 | cds-NP_013721.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:210670-212658:+ | gene-YMR008C_BG1 | rna-NM_001182504.1_BG1 | cds-NP_013721.1_BG1 | 99.2 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:270155-272148:- | gene-YMR008C_Bruggeman | rna-NM_001182504.1_Bruggeman | cds-NP_013721.1_Bruggeman | 98.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:272649-274637:- | gene-YMR008C_CAT1 | rna-NM_001182504.1_CAT1 | cds-NP_013721.1_CAT1 | 99.2 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:263147-265141:- | gene-YMR008C_CBS1585 | rna-NM_001182504.1_CBS1585 | cds-NP_013721.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:268691-270667:- | gene-YMR008C_CBS436 | rna-NM_001182504.1_CBS436 | cds-NP_013721.1_CBS436 | 98.6 | 99.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:376551-378545:- | gene-YMR008C_CBS6412 | rna-NM_001182504.1_CBS6412 | cds-NP_013721.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:262403-264397:- | gene-YMR008C_CBS6413 | rna-NM_001182504.1_CBS6413 | cds-NP_013721.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:275320-277314:- | gene-YMR008C_CENPK1137D | rna-NM_001182504.1_CENPK1137D | cds-NP_013721.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:262954-264948:- | gene-YMR008C_EthanolRed | rna-NM_001182504.1_EthanolRed | cds-NP_013721.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:266136-268130:- | gene-YMR008C_FaliES1 | rna-NM_001182504.1_FaliES1 | cds-NP_013721.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:168802-170790:+ | gene-YMR008C_JAY291 | rna-NM_001182504.1_JAY291 | cds-NP_013721.1_JAY291 | 99.2 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:267883-269859:- | gene-YMR008C_MUCL30387 | rna-NM_001182504.1_MUCL30387 | cds-NP_013721.1_MUCL30387 | 98.8 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:272540-274534:- | gene-YMR008C_MUCL30388 | rna-NM_001182504.1_MUCL30388 | cds-NP_013721.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:263432-265426:- | gene-YMR008C_MUCL39482 | rna-NM_001182504.1_MUCL39482 | cds-NP_013721.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:269242-271218:- | gene-YMR008C_MUCL42920 | rna-NM_001182504.1_MUCL42920 | cds-NP_013721.1_MUCL42920 | 98.7 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:280544-282538:- | gene-YMR008C_NCIM3186 | rna-NM_001182504.1_NCIM3186 | cds-NP_013721.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:263349-265343:- | gene-YMR008C_NCYC1407 | rna-NM_001182504.1_NCYC1407 | cds-NP_013721.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:269283-271271:- | gene-YMR008C_PE2H3 | rna-NM_001182504.1_PE2H3 | cds-NP_013721.1_PE2H3 | 99.2 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:275378-277366:- | gene-YMR008C_PE2H4 | rna-NM_001182504.1_PE2H4 | cds-NP_013721.1_PE2H4 | 99.2 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:280590-282584:- | gene-YMR008C_S288C | rna-NM_001182504.1_S288C | cds-NP_013721.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:255689-257677:+ | gene-YMR008C_SA1 | rna-NM_001182504.1_SA1 | cds-NP_013721.1_SA1 | 99.2 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:263205-265199:- | gene-YMR008C_ThermosaccDry | rna-NM_001182504.1_ThermosaccDry | cds-NP_013721.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:267170-269158:- | gene-YMR008C_VR1 | rna-NM_001182504.1_VR1 | cds-NP_013721.1_VR1 | 99.3 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:242260-244254:- | gene-YMR008C_ZTW1 | rna-NM_001182504.1_ZTW1 | cds-NP_013721.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:274716-276692:- | gene-YMR008C_Sparadoxus | rna-NM_001182504.1_Sparadoxus | cds-NP_013721.1_Sparadoxus | 90.3 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |