Gene name: PKP1
Reference locus (S288C): YIL042C
Gene biotype: protein_coding
Description: Mitochondrial protein kinase; involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p
Top 10 interactors (score): PDA1 (0.924); PTC5 (0.863); PTC6 (0.825); HUL4 (0.823); RKR1 (0.819); PKP2 (0.795); YPK2 (0.75); SCH9 (0.734); MRPL11 (0.708); KKQ8 (0.696); PDB1 (0.687); IKS1 (0.684); SPS1 (0.676); BUD32 (0.655); YPK3 (0.642); YPK1 (0.642); CDC45 (0.641); SKY1 (0.62); PSK1 (0.609); PTC4 (0.598)
Homologues (species, bitscore): BCKDK (Homo sapiens, 125.2); Bckdk (Mus musculus, 124.8); bckdk (Danio rerio, 133.7); bckdk (Xenopus tropicalis, 100.1); Pdk (Drosophila melanogaster, 87.8); pdhk-2 (Caenorhabditis elegans, 71.6); PDK (Arabidopsis thaliana, 94.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:271936-273120:- | gene-YIL042C_AKU4011 | rna-NM_001179392.1_AKU4011 | cds-NP_012222.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:133373-134557:- | gene-YIL042C_BG1 | rna-NM_001179392.1_BG1 | cds-NP_012222.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:278205-279389:- | gene-YIL042C_Bruggeman | rna-NM_001179392.1_Bruggeman | cds-NP_012222.1_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:266107-267291:- | gene-YIL042C_CAT1 | rna-NM_001179392.1_CAT1 | cds-NP_012222.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:271761-272945:- | gene-YIL042C_CBS1585 | rna-NM_001179392.1_CBS1585 | cds-NP_012222.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:267081-268265:- | gene-YIL042C_CBS436 | rna-NM_001179392.1_CBS436 | cds-NP_012222.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:268376-269560:- | gene-YIL042C_CBS6412 | rna-NM_001179392.1_CBS6412 | cds-NP_012222.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:263927-265111:- | gene-YIL042C_CBS6413 | rna-NM_001179392.1_CBS6413 | cds-NP_012222.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:267021-268205:- | gene-YIL042C_CENPK1137D | rna-NM_001179392.1_CENPK1137D | cds-NP_012222.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:255850-257034:- | gene-YIL042C_EthanolRed | rna-NM_001179392.1_EthanolRed | cds-NP_012222.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:273389-274573:- | gene-YIL042C_FaliES1 | rna-NM_001179392.1_FaliES1 | cds-NP_012222.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000365.1:24297-25481:+ | gene-YIL042C_JAY291 | rna-NM_001179392.1_JAY291 | cds-NP_012222.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:275053-276237:- | gene-YIL042C_MUCL30387 | rna-NM_001179392.1_MUCL30387 | cds-NP_012222.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:271656-272840:- | gene-YIL042C_MUCL30388 | rna-NM_001179392.1_MUCL30388 | cds-NP_012222.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:272604-273788:- | gene-YIL042C_MUCL39482 | rna-NM_001179392.1_MUCL39482 | cds-NP_012222.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:275748-276932:- | gene-YIL042C_MUCL42920 | rna-NM_001179392.1_MUCL42920 | cds-NP_012222.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:275108-276292:- | gene-YIL042C_NCIM3186 | rna-NM_001179392.1_NCIM3186 | cds-NP_012222.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:276877-278061:- | gene-YIL042C_NCYC1407 | rna-NM_001179392.1_NCYC1407 | cds-NP_012222.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:270135-271319:- | gene-YIL042C_PE2H3 | rna-NM_001179392.1_PE2H3 | cds-NP_012222.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:264841-266025:- | gene-YIL042C_PE2H4 | rna-NM_001179392.1_PE2H4 | cds-NP_012222.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:275108-276292:- | gene-YIL042C_S288C | rna-NM_001179392.1_S288C | cds-NP_012222.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:49868-51052:+ | gene-YIL042C_SA1 | rna-NM_001179392.1_SA1 | cds-NP_012222.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:272058-273242:- | gene-YIL042C_ThermosaccDry | rna-NM_001179392.1_ThermosaccDry | cds-NP_012222.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:269243-270427:- | gene-YIL042C_VR1 | rna-NM_001179392.1_VR1 | cds-NP_012222.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:245912-247096:- | gene-YIL042C_ZTW1 | rna-NM_001179392.1_ZTW1 | cds-NP_012222.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:268000-269184:- | gene-YIL042C_Sparadoxus | rna-NM_001179392.1_Sparadoxus | cds-NP_012222.1_Sparadoxus | 90.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |